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2013 | OriginalPaper | Buchkapitel

8. Viral Kinetic Modeling of Chronic Hepatitis C and B Infection

verfasst von : Eva Herrmann, Yusuke Asai

Erschienen in: Nonautonomous Dynamical Systems in the Life Sciences

Verlag: Springer International Publishing

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Abstract

Chronic infection with hepatitis C or hepatitis B virus are important world-wide health problems leading to long-term damage of the liver. There are, however, treatment options which can lead to viral eradication in hepatitis C or long-term viral suppression in hepatitis B in some patients. Nevertheless, there is still room for improvement. Mathematical compartment models based on ordinary differential equation systems have successfully been applied to improve antiviral treatment. Here, we illustrate how mathematical and statistical analysis of such models influenced clinical research and give an overview on the most important models for hepatitis C and hepatitis B viral kinetics.

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Metadaten
Titel
Viral Kinetic Modeling of Chronic Hepatitis C and B Infection
verfasst von
Eva Herrmann
Yusuke Asai
Copyright-Jahr
2013
DOI
https://doi.org/10.1007/978-3-319-03080-7_8