Skip to main content
Erschienen in: Microsystem Technologies 4/2022

11.03.2022 | Technical Paper

A high gain low noise amplifier for implantable cardio technologies

verfasst von: P. Vijaya Lakshmi, Sarada Musala, Avireni Srinivasulu

Erschienen in: Microsystem Technologies | Ausgabe 4/2022

Einloggen

Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.

search-config
loading …

Abstract

Increase in large number of neurological and cardiovascular illness that cannot be treated by medicine alone have brought about a critical development in the quantity of patients that require implantable electronic gadgets. These gadgets ordinarily contain a sensor to distinguish quiet biomarkers. However, the detected signals are extremely feeble to be further processed and are easily prone to noise. Henceforth, a low noise amplifier (LNA) is utilized post sensor to intensify the frail signal and to decrease the impact of noise. These amplifiers in implants present explicit designing difficulties, including low power utilization and low noise performance. This paper mainly focuses on the low power, high gain, and low noise amplifier suitable for ECG signal acquisition systems to record the electrical motion of a patient’s heart. As LNA is the most power thirsty block of the signal acquisition system, low power LNA suitable for cardio implantable technologies are reviewed and based on the review, a customized LNA design for the respective application is proposed. Proposed LNA is a two-stage operational transconductance amplifier (OTA) whose self-biased driving circuit of the second stage is embedded in the output path of the first stage to reuse current of the first stage. It is designed using 45 nm CMOS technology files, and provides a gain of 42.3 dB, while consuming a power of only 153 nW from 1.2 V single power supply and with an input referred noise of 1.5 μVrms. The proposed amplifier performance satisfies the required parameters of the cardiac implantable devices.

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 390 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Maschinenbau + Werkstoffe




 

Jetzt Wissensvorsprung sichern!

Literatur
Zurück zum Zitat Bhargav A, Srinivasulu A, Pal D (2018) An operational transconductance amplifiers based sinusoidal oscillator using CNTFETs. In: Proc of the 23rd IEEE international conference on applied electronics (IEEE ICAE-2018), Pilsen, Czech Republic, p 6. https://doi.org/10.23919/AE.2018.8501428 Bhargav A, Srinivasulu A, Pal D (2018) An operational transconductance amplifiers based sinusoidal oscillator using CNTFETs. In: Proc of the 23rd IEEE international conference on applied electronics (IEEE ICAE-2018), Pilsen, Czech Republic, p 6. https://​doi.​org/​10.​23919/​AE.​2018.​8501428
Zurück zum Zitat Chen YP et al (2015) An injectable 64 nW ECG mixed-signal SoC in 65 nmfor arrhythmia monitoring. IEEE J Solid-State Circ 50(1):375–390CrossRef Chen YP et al (2015) An injectable 64 nW ECG mixed-signal SoC in 65 nmfor arrhythmia monitoring. IEEE J Solid-State Circ 50(1):375–390CrossRef
Zurück zum Zitat Harrison RR (2008) The design of integrated circuits to observe brain activity. Proc IEEE 96(7):1203–1216CrossRef Harrison RR (2008) The design of integrated circuits to observe brain activity. Proc IEEE 96(7):1203–1216CrossRef
Zurück zum Zitat Rai S, Holleman J, Pandey J, Zhang F, Otis B (2009) A 500 µW neural tag with 2 µVrms AFE and frequency-multiplying MICS/ISMFSK transmitter. In: Proc. IEEE Int. Solid-State Circuits Conf., Dig.Tech. Papers, pp 212–213 Rai S, Holleman J, Pandey J, Zhang F, Otis B (2009) A 500 µW neural tag with 2 µVrms AFE and frequency-multiplying MICS/ISMFSK transmitter. In: Proc. IEEE Int. Solid-State Circuits Conf., Dig.Tech. Papers, pp 212–213
Zurück zum Zitat Raj N, Sharma RK, Jasuja A, Garg R (2010) A low power OTA for biomedical applications. J Sel Areas Bioeng 2010:5 Raj N, Sharma RK, Jasuja A, Garg R (2010) A low power OTA for biomedical applications. J Sel Areas Bioeng 2010:5
Zurück zum Zitat Song S et al (2015b) A low-voltage chopper-stabilized amplifier for fetal ECG monitoring with a 1.41 power efficiency factor. IEEE Trans Biomed Circ Syst 9(2):237–247CrossRef Song S et al (2015b) A low-voltage chopper-stabilized amplifier for fetal ECG monitoring with a 1.41 power efficiency factor. IEEE Trans Biomed Circ Syst 9(2):237–247CrossRef
Zurück zum Zitat Srinivasulu A, Sowjanya G, Gautham SH, Pitchaiah T, Krishna VVSV (2017) Operational transconductance amplifiers based sinusoidal oscillator with grounded capacitors. In: Lecture notes in electrical engineering (LNEE) (Springer), Chapter No: 28, vol 403, pp 343–352. https://doi.org/10.1007/978-981-10-2999-8_28 Srinivasulu A, Sowjanya G, Gautham SH, Pitchaiah T, Krishna VVSV (2017) Operational transconductance amplifiers based sinusoidal oscillator with grounded capacitors. In: Lecture notes in electrical engineering (LNEE) (Springer), Chapter No: 28, vol 403, pp 343–352. https://​doi.​org/​10.​1007/​978-981-10-2999-8_​28
Zurück zum Zitat Wang TY, Lai MR, Twigg CM, Peng SY (2014a) A fully reconfigurablelow-noise biopotential sensing amplifier with 1.96 noise efficiency factor. IEEE Trans Biomed Circ Syst 8(3):411–422CrossRef Wang TY, Lai MR, Twigg CM, Peng SY (2014a) A fully reconfigurablelow-noise biopotential sensing amplifier with 1.96 noise efficiency factor. IEEE Trans Biomed Circ Syst 8(3):411–422CrossRef
Zurück zum Zitat Webster JG (1995) Medical instrumentation: application and design. Wiley, New York Webster JG (1995) Medical instrumentation: application and design. Wiley, New York
Zurück zum Zitat Yazicioglu RF, Kim S, Torfs T, Kim H, Hoof CV (2011) A 30 μWanalog signal processor ASIC for portable biopotential signal monitoring. IEEE J Solid-State Circ 46(1):209–223CrossRef Yazicioglu RF, Kim S, Torfs T, Kim H, Hoof CV (2011) A 30 μWanalog signal processor ASIC for portable biopotential signal monitoring. IEEE J Solid-State Circ 46(1):209–223CrossRef
Metadaten
Titel
A high gain low noise amplifier for implantable cardio technologies
verfasst von
P. Vijaya Lakshmi
Sarada Musala
Avireni Srinivasulu
Publikationsdatum
11.03.2022
Verlag
Springer Berlin Heidelberg
Erschienen in
Microsystem Technologies / Ausgabe 4/2022
Print ISSN: 0946-7076
Elektronische ISSN: 1432-1858
DOI
https://doi.org/10.1007/s00542-022-05260-5

Weitere Artikel der Ausgabe 4/2022

Microsystem Technologies 4/2022 Zur Ausgabe