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Polymer Bulletin
Erschienen in: Polymer Bulletin 11/2021

23.10.2020 | Original Paper

Antibacterial Polypeptide nisin containing cotton modified hydrogel composite wound dressings

verfasst von: Oylum Colpankan Gunes, Aylin Ziylan Albayrak

Erschienen in: Polymer Bulletin | Ausgabe 11/2021

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Abstract

The objective of the study was to produce modified cotton hydrogel composite wound dressings by antibacterial nisin incorporation and biocompatible carboxymethyl chitosan (CMCht):alginate impregnation. To the best of our knowledge, this is the first study where an antibacterial polypeptide nisin containing hydrogel wound dressing was obtained for wound healing application. The produced hydrogel composite wound dressings retained their porous structures after polymer modification as well as they had an appropriate water vapor transmission rate. Furthermore, because of their hydrogel structures they had a high water up-take capacity and exhibited viscoelastic properties. They also had an antibacterial activity against gram-positive Staphylococcus aureus bacteria and no cytotoxicity on fibroblast cell. Texture profile analysis was used to obtain the mechanical properties of wound dressing for the first time and it was observed that wound dressings had a high compressive strength. Consequently, the produced hydrogel composite wound dressings would be suitable as a short-term dressing material for acute wounds.
Vorheriger Artikel Improved filter media with PVA/citric acid/Triton X-100 nanofibers for filtration of nanoparticles from air
Nächster Artikel Electrospun polyvinyl alcohol (PVA) nanofibers as carriers for hormones (IAA and GA3) delivery in seed invigoration for enhancing germination and seedling vigor of agricultural crops (groundnut and black gram)

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Metadaten
Titel
Antibacterial Polypeptide nisin containing cotton modified hydrogel composite wound dressings
verfasst von
Oylum Colpankan Gunes
Aylin Ziylan Albayrak
Publikationsdatum
23.10.2020
Verlag
Springer Berlin Heidelberg
Erschienen in
Polymer Bulletin / Ausgabe 11/2021
Print ISSN: 0170-0839
Elektronische ISSN: 1436-2449
DOI
https://doi.org/10.1007/s00289-020-03429-4

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