Skip to main content
Fachgebiete
Automobil + Motoren Bauwesen + Immobilien Business IT + Informatik Elektrotechnik + Elektronik Energie + Nachhaltigkeit Finance + Banking Management + Führung Marketing + Vertrieb Maschinenbau + Werkstoffe Versicherung + Risiko
DE
EN
Themenseiten
Organisationspsychologie Projektmanagement Marketing Smart Manufacturing
Bücher
Zeitschriften
Weitere Formate
Podcasts Webinare Technik Webinare Wirtschaft Kongresse Veranstaltungskalender Awards
Jetzt Einzelzugang starten
Zugang für Unternehmen
Referenzkunden
MTZ-Fachkongress

Antriebe und Energiesysteme von morgen


Austausch von Automobil- und Energiewirtschaft

Am 14./15. Mai geht es in Chemnitz um die Mobilitätswende durch Elektro- und Wasserstofffahrzeuge.
Erweiterte Suche
Anmelden
nach oben
Polymer Bulletin
Erschienen in: Polymer Bulletin 8/2023

28.09.2022 | Original Paper

Assessing the potential of galactomannan isolated from six varieties of Cyamopsis tetragonoloba L. for hydrogel formation and controlled drug delivery

verfasst von: Sheena Jobin Alooparampil, Jigna G. Tank

Erschienen in: Polymer Bulletin | Ausgabe 8/2023

Einloggen

Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.

search-config
loading …

Abstract

In the present studies, polysaccharide was extracted from 6 varieties of Cyamopsis tetragonoloba L. and its potential to form hydrogel was evaluated. The hydrogel formation was not observed in Desi and Neelam 51 variety but it formed particulate matter. Parasiya 954 and Maharani 92 formed intact, sticky, and watery gel whereas Swati and Nylon 55 formed intact, dense, and sticky gel with high water absorbing and swelling property. The rheological analysis of hydrogels (C, Pr2A, Mh2A, Sw2A, & Ny2A) suggested that they had a weak, flexible network structure and behaved as dilatant shear thickening fluid. The strength of Ny2A and Sw2A was high as compared to C, Pr2A, and Mh2A. The FESEM, FTIR, and XRD analysis of drug-loaded hydrogels confirmed the formation of polymerization in intact and sticky hydrogels, porous morphology, entrapment of insulin in hydrogels, the stable structure of insulin is retained and its amorphous dispersion in hydrogels, respectively. The in vitro controlled drug release was evaluated from each hydrogel by using insulin as a model drug using the Korsmeyer-Peppas model. The controlled drug (insulin) release was observed in formulations C, Pr2A, Mh2A, Sw2A, Ny2A, and Mh3A whereas controlled drug release was not observed in formulations Pr3A, Sw3A, Ny3A.
Vorheriger Artikel Production and mechanical characterization of reinforced zinc oxide nanoparticle-coated silk waste bio-composites
Nächster Artikel Guiding mesenchymal stem cells differentiation into chondrocytes using sulfated alginate/cold atmospheric plasma modified polycaprolactone nanofibrous scaffold

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Jetzt informieren

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 390 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Maschinenbau + Werkstoffe




 

Jetzt Wissensvorsprung sichern!

Jetzt informieren
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Liyanage S, Abidi N, Auld D et al (2015) Chemical and physical characterization of galactomannan extracted from guar cultivars (Cyamopsis tetragonolobus L.). Ind Crops Prod 74:388–396
2.
Srivastava M, Kapoor VP (2005) Seed galactomannans: an overview. Chem Biodivers 2(3):295–317PubMed
3.
Prajapati VD, Jani GK, Moradiya NG et al (2013) Galactomannan: a versatile biodegradable seed polysaccharide. Int J Biol Macromol 60:83–92PubMed
4.
Thakura S, Sharma B, Verma A et al (2018) Recent approaches in guar gum hydrogel synthesis for water purification. Int J Polym Anal Charact 23(7):621–632
5.
Rithe SS, Kadam PG, Mhaske ST (2014) Preparation and analysis of novel hydrogels prepared from the blend of guar gum and chitosan: cross-linked with glutaraldehyde. Adv Mater Sci Eng 2:1–15
6.
Elsaeed SM, Zaki EG, Omar WA et al (2021) Guar gum-based hydrogels as potent green polymers for enhanced oil recovery in high-salinity reservoirs. ACS Omega 6(36):23421–23431PubMedPubMedCentral
7.
Chen X, Martin BD, Neubauer TK et al (1995) Enzymatic and chemoenzymatic approaches to synthesis of sugar based polymer and hydrogels. Carbohydr Polym 28:15–21
8.
Kashyap N, Kumar N, Kumar M (2005) Hydrogels for pharmaceutical and biomedical applications. Crit Rev Ther Drug Carr Syst 22:107–149
9.
Hamidi M, Azadi A, Rafiei P (2008) Hydrogel nanoparticles in drug delivery. Adv Drug Deliv Rev 60(15):1638–1649PubMed
10.
Singh A, Sharma PK, Garg VK et al (2010) Hydrogels: a review. Int J Pharm Sci Rev Res 4(2):97–105
11.
Zhang L, Li K, Xiao W et al (2011) Preparation of collagen–chondroitin sulfate–hyaluronic acid hybrid hydrogel scaffolds and cell compatibility in vitro. Carbohydr Polym 84(1):118–125
12.
Saul JM, Williams DF (2011) Hydrogels in regenerative medicine. Handbook of polymer applications in medicine and medical devices. William Andrew Publishing, pp 279–302
13.
Hiremath JN, Vishalakshi B (2012) Effect of crosslinking on swelling behaviour of IPN hydrogels of guar gum & polyacrylamide. Der Pharma Chemica 4(3):946–955
14.
Verma D, Sharma SK (2021) Recent advances in guar gum based drug delivery systems and their administrative routes. Int J Biol Macromol 181:653–671PubMed
15.
Sullad AG, Manjeshwar LS, Aminabhavi TM (2010) Novel pH-sensitive hydrogels prepared from the blends of poly(vinyl alcohol) with acrylic acid-graft-guar gum matrixes for isoniazid delivery. Ind Eng Chem Res 49:7323–7329
16.
Soppimath KS, Kulkarni AR, Aminabhavi TM (2000) Controlled release of antihypertensive drug from the interpenetrating network poly (vinyl alcohol)–guar gum hydrogel microspheres. J Biomater Sci Polym Ed 11(1):27–43PubMed
17.
Palem RR, Shimoga G, Rao KSV et al (2020) Guar gum graft polymer-based silver nanocomposite hydrogels: synthesis, characterization and its biomedical applications. J Polym Res 27(3):1–20
18.
Kumar B, Murali A, Bharath AB et al (2019) Guar gum modified upconversion nanocomposites for colorectal cancer treatment through enzyme-responsive drug release and NIR-triggered photodynamic therapy. Nanotechnology 30(31):315102PubMed
19.
Chen LG, Liu ZL, Zhuo RX (2005) Synthesis and properties of degradable hydrogels of konjac glucomannan grafted acrylic acid for colon-specific drug delivery. Polymer 46(16):6274–6281
20.
Bashir S, Teo YY, Ramesh S et al (2016) Synthesis, characterization, properties of N-succinyl chitosan-g-poly (methacrylic acid) hydrogels and in vitro release of theophylline. Polymer 92:36–49
21.
Takehara H, Hadano Y, Kanda Y, Ichiki T (2020) Effect of the thermal history on the crystallinity of poly (L-lactic Acid) during the micromolding process. Micromachines 11(5):452PubMedPubMedCentral
22.
Paixão MVG, de Carvalho BR (2018) Application of guar gum in brine clarification and oily water treatment. Int J Biol Macromol 108:119–126PubMed
23.
Shabir F, Erum A, Tulain UR et al (2017) Preparation and characterization of pH sensitive crosslinked Linseed polysaccharides-co-acrylic acid/methacrylic acid hydrogels for controlled delivery of ketoprofen. Des Monomers Polym 20(1):485–495PubMedPubMedCentral
24.
Gulrez SK, Al-Assaf S, Phillips GO (2011) Hydrogels: methods of preparation, characterisation and applications. In: Progress in molecular and environmental bioengineering-from analysis and modeling to technology applications, pp 117–150
25.
Nagasawa N, Yagi T, Kume T et al (2004) Radiation crosslinking of carboxymethyl starch. Carbohydr Polym 58(2):109–113
26.
Lin WJ, Lu CH (2002) Characterization and permeation of microporous poly (ε-caprolactone) films. J Membr Sci 198(1):109–118
27.
Ranjha NM, Hanif M, Afzal Z et al (2015) Diffusion coefficient, porosity measurement, dynamic and equilibrium swelling studies of Acrylic acid/Polyvinyl alcohol (AA/PVA) hydrogels. Pak J Pharm Res 1(2):48–57
28.
Kokol V, Pottathara YB, Mihelčič M et al (2021) Rheological properties of gelatine hydrogels affected by flow-and horizontally-induced cooling rates during 3D cryo-printing. Colloids Surf A Physicochem Eng Asp 616:126356
29.
Abd El-Mohdy HL, Hegazy EA, El-Nesr EM et al (2016) Synthesis, characterization and properties of radiation-induced Starch/(EG-co-MAA) hydrogels. Arab J Chem 9:S1627–S1635
30.
Shah N, Patel K (2014) Formulation and development of hydrogel for poly acrylamide-co-acrylic acid. J Pharm Sci Biosci Res Patel 4:114–120
31.
Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72(1–2):248–254PubMed
32.
Hammer Ø, Harper DA, Ryan PD (2001) PAST: paleontological statistics software package for education and data analysis. Palaeontol Electron 4(1):9
33.
Mudgil D, Barak S, Khatkar BS (2012) X-ray diffraction, IR spectroscopy and thermal characterization of partially hydrolyzed guar gum. Int J Biol Macromol 50(4):1035–1039PubMed
34.
Warrand J, Michaud P, Picton L et al (2005) Structural investigations of the neutral polysaccharide of Linum usitatissimum L. seeds mucilage. Int J Biol Macromol 35(3–4):121–125PubMed
35.
Kačuráková M, Belton PS, Wilson RH et al (1998) Hydration properties of xylan-type structures: an FTIR study of xylooligosaccharides. J Sci Food Agric 77(1):38–44
36.
Kačuráková M, Ebringerova A, Hirsch J et al (1994) Infrared study of arabinoxylans. J Sci Food Agric 66(3):423–427
37.
Thombare N, Mishra S, Siddiqui MZ et al (2018) Design and development of guar gum based novel, superabsorbent and moisture retaining hydrogels for agricultural applications. Carbohydr Polym 185:169–178PubMed
38.
Fringant C, Tvaroska I, Mazeau K et al (1995) Hydration of α-maltose and amylose: molecular modelling and thermodynamics study. Carbohydr Res 278(1):27–41PubMed
39.
Mudgil D, Barak S, Khatkar BS (2012) Effect of enzymatic depolymerization on physicochemical and rheological properties of guar gum. Carbohyd Polym 90(1):224–228
40.
Tayal A, Pai VB, Khan SA (1999) Rheology and microstructural changes during enzymatic degradation of a guar−borax hydrogel. Macromolecules 32(17):5567–5574
41.
Jafry HR, Pasquali M, Barron AR (2011) Effect of functionalized nanomaterials on the rheology of borate cross-linked guar gum. Ind Eng Chem Res 50(6):3259–3264
42.
Bishop M, Shahid N, Yang J et al (2004) Determination of the mode and efficacy of the cross-linking of guar by borate using MAS 11B NMR of borate cross-linked guar in combination with solution 11B NMR of model systems. Dalton Trans 17:2621–2634
43.
Mesmer RE, Baes CF, Sweeton FH (1972) Acidity measurements at elevated temperatures: VI. Boric acid equilibriums. Inorg Chem 11:537–543
44.
Wang S, Tang H, Guo J et al (2016) Effect of pH on the rheological properties of borate crosslinked hydroxypropyl guar gum hydrogel and hydroxypropyl guar gum. Carbohydr Polym 147:455–463PubMed
45.
Harris PC (1993) Chemistry and rheology of borate-crosslinked fluids attemperatures to 300 F. J Pet Technol 45:264–269
46.
Sharma K, Kumar V, Chaudhary B et al (2016) Application of biodegradable superabsorbent hydrogel composite based on Gum ghatti-co-poly (acrylic acid-aniline) for controlled drug delivery. Polym Degrad Stab 124:101–111
47.
Amin MCIM, Ahmad N, Halib N et al (2012) Synthesis and characterization of thermo-and pH-responsive bacterial cellulose/acrylic acid hydrogels for drug delivery. Carbohydr Polym 88(2):465–473
48.
Zhang J, Chu LY, Cheng CJ et al (2008) Graft-type poly (N-isopropylacrylamide-co-acrylic acid) microgels exhibiting rapid thermo-and pH-responsive properties. Polymer 49(10):2595–2603
49.
Mahdavinia GR, Pourjavadi A, Hosseinzadeh H et al (2004) Modified chitosan 4. Superabsorbent hydrogels from poly (acrylic acid-co-acrylamide) grafted chitosan with salt-and pH-responsiveness properties. Eur Polym J 40(7):1399–1407
50.
Ranjha NM, Qureshi UF (2014) Preparation and characterization of crosslinked acrylic acid/hydroxypropyl methyl cellulose hydrogels for drug delivery. Int J Pharm Pharm Sci 6(4):400–410
51.
Pourjavadi A, Barzegar S, Mahdavinia GR (2006) MBA-crosslinked Na-Alg/CMC as a smart full-polysaccharide superabsorbent hydrogels. Carbohydr Polym 66(3):386–395
52.
Ranjha NM, Ayub G, Naseem S et al (2010) Preparation and characterization of hybrid pH-sensitive hydrogels of chitosan-co-acrylic acid for controlled release of verapamil. J Mater Sci Mater Med 21(10):2805–2816PubMed
53.
Soleimani F, Sadeghi M (2012) Synthesis of pH-sensitive hydrogel based on starch-polyacrylate superabsorbent. J Biomater Nanobiotechnol 3(2A):310–314
54.
Highley CB, Rodell CB, Burdick JA (2015) Direct 3D printing of shear-thinning hydrogels into self-healing hydrogels. Adv Mater 27(34):5075–5079PubMed
55.
Sittikijyothin W, Sampaio P, Goncalves MP (2007) Heat-induced gelation of-lactoglobulin at varying pH: effect of tara gum on the rheological andstructural properties of the gels. Food Hydrocoll 21:1046–1055
56.
Ritger PL, Peppas NA (1987) A simple equation for description of solute release I. Fickian and non-fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs. JCR 5(1):23–36
57.
Ritger PL, Peppas NA (1987) A simple equation for description of solute release II. Fickian and anomalous release from swellable devices. JCR 5(1):37–42
Metadaten
Titel
Assessing the potential of galactomannan isolated from six varieties of Cyamopsis tetragonoloba L. for hydrogel formation and controlled drug delivery
verfasst von
Sheena Jobin Alooparampil
Jigna G. Tank
Publikationsdatum
28.09.2022
Verlag
Springer Berlin Heidelberg
Erschienen in
Polymer Bulletin / Ausgabe 8/2023
Print ISSN: 0170-0839
Elektronische ISSN: 1436-2449
DOI
https://doi.org/10.1007/s00289-022-04483-w

Weitere Artikel der Ausgabe 8/2023

Polymer Bulletin 8/2023 Zur Ausgabe

Original Paper

Effect of nanocrystalline cellulose/silica-based fillers on mechanical properties of experimental dental adhesive

Original Paper

Investigation on optical, structural and electrochemical properties of hybrid PVA/ZnWMoO7 nanocomposite film for optoelectronics and super capacitor applications

Original Paper

Water decontamination in terms of Hg(II) over thiol immobilized magnesium ferrite: Gum Arabic biosorbent—response surface optimization, kinetic, isotherm and comparing study

Original Paper

Elaboration and characterization of new adsorbents based on conducting PANI/zeolite HY/TiO2 nanocomposite applied for chromate adsorption

Original Paper

Influence of processing oil on properties of dynamically cured epoxidized natural rubber and thermoplastic polyurethane blends

Original Paper

Fabrication of electrospun polyamide–weathered basalt nano-composite as a non-conventional membrane for basic and acid dye removal

Premium Partner

    Marktübersichten

    Die im Laufe eines Jahres in der „adhäsion“ veröffentlichten Marktübersichten helfen Anwendern verschiedenster Branchen, sich einen gezielten Überblick über Lieferantenangebote zu verschaffen. 

    Zur Marktübersicht
    Bildnachweise