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Erschienen in: Cognitive Computation 4/2016

01.08.2016

Deep Belief Networks for Quantitative Analysis of a Gold Immunochromatographic Strip

verfasst von: Nianyin Zeng, Zidong Wang, Hong Zhang, Weibo Liu, Fuad E. Alsaadi

Erschienen in: Cognitive Computation | Ausgabe 4/2016

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Abstract

Gold immunochromatographic strip (GICS) has become a popular membrane-based diagnostic tool in a variety of settings due to its sensitivity, simplicity and rapidness. This paper aimed to develop a framework of automatic image inspection to further improve the sensitivity as well as the quantitative performance of the GICS systems. As one of the latest methodologies in machine learning, the deep belief network (DBN) is applied, for the first time, to quantitative analysis of GICS images with hope to segment the test and control lines with a high accuracy. It is remarkable that the exploited DBN is capable of simultaneously learning three proposed features including intensity, distance and difference to distinguish the test and control lines from the region of interest that are obtained by preprocessing the GICS images. Several indices are proposed to evaluate the proposed method. The experiment results show the feasibility and effectiveness of the DBN in the sense that it provides a robust image processing methodology for quantitative analysis of GICS.

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Literatur
1.
Zurück zum Zitat Chuang L, Hwang J, Chang H, Chang F, Jong SH. Rapid and simple quantitative measurement of \(\alpha \)-fetoprotein by combining immunochromatographic strip test and artificial neural network image analysis system. Clin Chim Acta. 2004;348:87–93.CrossRefPubMed Chuang L, Hwang J, Chang H, Chang F, Jong SH. Rapid and simple quantitative measurement of \(\alpha \)-fetoprotein by combining immunochromatographic strip test and artificial neural network image analysis system. Clin Chim Acta. 2004;348:87–93.CrossRefPubMed
2.
Zurück zum Zitat Ding D, Wang Z, Shen B, Wei G. Event-triggered consensus control for discrete-time stochastic multi-agent systems: the input-to-state stability in probability. Automatica. 2015;62:284–91.CrossRef Ding D, Wang Z, Shen B, Wei G. Event-triggered consensus control for discrete-time stochastic multi-agent systems: the input-to-state stability in probability. Automatica. 2015;62:284–91.CrossRef
3.
Zurück zum Zitat Ding D, Wang Z, Lam J, Shen B. Finite-horizon \(H_{\infty }\) control for discrete time-varying systems with randomly occurring nonlinearities and fading measurements. IEEE Trans Autom Control. 2015;60(9):2488–93.CrossRef Ding D, Wang Z, Lam J, Shen B. Finite-horizon \(H_{\infty }\) control for discrete time-varying systems with randomly occurring nonlinearities and fading measurements. IEEE Trans Autom Control. 2015;60(9):2488–93.CrossRef
4.
Zurück zum Zitat Ding D, Wang Z, Shen B, Dong H. \(H_{\infty }\) state estimation with fading measurements, randomly varying nonlinearities and probabilistic distributed delays. Int J Robust Nonlinear Control. 2015;25(13):2180–95. Ding D, Wang Z, Shen B, Dong H. \(H_{\infty }\) state estimation with fading measurements, randomly varying nonlinearities and probabilistic distributed delays. Int J Robust Nonlinear Control. 2015;25(13):2180–95.
5.
Zurück zum Zitat Faulstich K, Gruler R, Eberhard M, Haberstroh K. Developing rapid mobile POC systems. Part 1: devices and applications for lateral-flow immunodiagnostics. IVD Technol. 2007;13(6):47–53. Faulstich K, Gruler R, Eberhard M, Haberstroh K. Developing rapid mobile POC systems. Part 1: devices and applications for lateral-flow immunodiagnostics. IVD Technol. 2007;13(6):47–53.
6.
Zurück zum Zitat Hamel P, Eck D. Learning features from music audio with deep belief networks. In: 11th international society for music information retrieval conference; 2010. p. 339–44 Hamel P, Eck D. Learning features from music audio with deep belief networks. In: 11th international society for music information retrieval conference; 2010. p. 339–44
7.
Zurück zum Zitat Hinton G. Training products of experts by minimizing contrastive divergence. Neural Comput. 2002;14(8):1771–800.CrossRefPubMed Hinton G. Training products of experts by minimizing contrastive divergence. Neural Comput. 2002;14(8):1771–800.CrossRefPubMed
8.
Zurück zum Zitat Hinton G, Deng L, Yu D, Dahl G, Mohamed A, Jaitly N, Senior A, Vanhoucke V, Nguyen P, Sainath T, Kingsbury B. Deep neural networks for acoustic modeling in speech recognition: the shared views of four research groups. IEEE Signal Process Mag. 2012;29(6):82–97.CrossRef Hinton G, Deng L, Yu D, Dahl G, Mohamed A, Jaitly N, Senior A, Vanhoucke V, Nguyen P, Sainath T, Kingsbury B. Deep neural networks for acoustic modeling in speech recognition: the shared views of four research groups. IEEE Signal Process Mag. 2012;29(6):82–97.CrossRef
9.
Zurück zum Zitat Hinton G, Salakhutdinov R. Reducing the dimensionality of data with neural networks. Science. 2006;313(5786):504–7.CrossRefPubMed Hinton G, Salakhutdinov R. Reducing the dimensionality of data with neural networks. Science. 2006;313(5786):504–7.CrossRefPubMed
10.
Zurück zum Zitat Hou N, Dong H, Wang Z, Ren W, Alsaadi FE. Non-fragile state estimation for discrete Markovian jumping neural networks. Neurocomputing. 2016;179:238–45.CrossRef Hou N, Dong H, Wang Z, Ren W, Alsaadi FE. Non-fragile state estimation for discrete Markovian jumping neural networks. Neurocomputing. 2016;179:238–45.CrossRef
11.
Zurück zum Zitat Huang L, Zhang Y, Xie Ch, Qu J, Huang H, Wang X. Research of reflectance photometer based on optical absorption. Int J Light Electron Opt. 2010;121(19):1725–8.CrossRef Huang L, Zhang Y, Xie Ch, Qu J, Huang H, Wang X. Research of reflectance photometer based on optical absorption. Int J Light Electron Opt. 2010;121(19):1725–8.CrossRef
12.
Zurück zum Zitat Kaur J, Singh K, Boro R, Thampi K, Raje M, Varshney G. Immunochromatographic dipstick assay format using gold nanoparticles labeled protein-hapten conjugate for the detection of atrazine. Environ Sci Technol. 2007;41(14):5028–36.CrossRefPubMed Kaur J, Singh K, Boro R, Thampi K, Raje M, Varshney G. Immunochromatographic dipstick assay format using gold nanoparticles labeled protein-hapten conjugate for the detection of atrazine. Environ Sci Technol. 2007;41(14):5028–36.CrossRefPubMed
13.
Zurück zum Zitat Li J, Ouellette A, Giovangrandi L, Cooper D, Ricco A, Kovacs G. Optical scanner for immunoassays with up-converting phosphorescent labels. IEEE Trans Biomed Eng. 2008;55(5):1560–71.CrossRefPubMed Li J, Ouellette A, Giovangrandi L, Cooper D, Ricco A, Kovacs G. Optical scanner for immunoassays with up-converting phosphorescent labels. IEEE Trans Biomed Eng. 2008;55(5):1560–71.CrossRefPubMed
14.
Zurück zum Zitat Li D, Wei S, Yang H, Li Y, Deng A. A sensitive immunochromatographic assay using colloidal gold-antibody probe for rapid detection of pharmaceutical indomethacin in water samples. Biosens Bioelectron. 2009;24(7):2277–80.CrossRefPubMed Li D, Wei S, Yang H, Li Y, Deng A. A sensitive immunochromatographic assay using colloidal gold-antibody probe for rapid detection of pharmaceutical indomethacin in water samples. Biosens Bioelectron. 2009;24(7):2277–80.CrossRefPubMed
15.
Zurück zum Zitat Li Y, Zeng N, Du M. A novel image methodology for interpretation of gold immunochromatographic strip. J Comput. 2011;6(3):540–7. Li Y, Zeng N, Du M. A novel image methodology for interpretation of gold immunochromatographic strip. J Comput. 2011;6(3):540–7.
16.
Zurück zum Zitat Lin C, Wu C, Hsu H, Li K, Lin L. Rapid bio-test strips reader with image processing technology. Optik. 2004;115(8):363–9.CrossRef Lin C, Wu C, Hsu H, Li K, Lin L. Rapid bio-test strips reader with image processing technology. Optik. 2004;115(8):363–9.CrossRef
17.
Zurück zum Zitat Liu Y, Alsaadi FE, Yin X, Wang Y. Robust \(H_{\infty }\) filtering for discrete nonlinear delayed stochastic systems with missing measurements and randomly occurring nonlinearities. Int J Gen Syst. 2015;44(2):169–81.CrossRef Liu Y, Alsaadi FE, Yin X, Wang Y. Robust \(H_{\infty }\) filtering for discrete nonlinear delayed stochastic systems with missing measurements and randomly occurring nonlinearities. Int J Gen Syst. 2015;44(2):169–81.CrossRef
18.
Zurück zum Zitat Luo Y, Wei G, Liu Y, Ding X. Reliable \(H_{\infty }\) state estimation for 2-D discrete systems with infinite distributed delays and incomplete observations. Int J Gen Syst. 2015;44(2):155–68.CrossRef Luo Y, Wei G, Liu Y, Ding X. Reliable \(H_{\infty }\) state estimation for 2-D discrete systems with infinite distributed delays and incomplete observations. Int J Gen Syst. 2015;44(2):155–68.CrossRef
19.
Zurück zum Zitat Mohamed A, Dahl G, Hinton G. Acoustic modeling using deep belief networks. IEEE Trans Audio Speech Lang Process. 2012;20(1):14–22.CrossRef Mohamed A, Dahl G, Hinton G. Acoustic modeling using deep belief networks. IEEE Trans Audio Speech Lang Process. 2012;20(1):14–22.CrossRef
20.
Zurück zum Zitat Mohamed A, Sainath T, Dahl G, Ramabhadran B, Hinton G, Picheny M. Deep belief networks using discriminative features for phone recognition. In: 2011 IEEE international conference on acoustics, speech and signal processing; 2011. p. 5060–63 Mohamed A, Sainath T, Dahl G, Ramabhadran B, Hinton G, Picheny M. Deep belief networks using discriminative features for phone recognition. In: 2011 IEEE international conference on acoustics, speech and signal processing; 2011. p. 5060–63
21.
Zurück zum Zitat Posthuma-Trumpie GA, Korf J, van Amerongen A. Lateral flow (immuno)assay: its strengths, weaknesses, opportunities and threats. A literature survey. Anal Bioanal Chem. 2009;393(2):569–82.CrossRefPubMed Posthuma-Trumpie GA, Korf J, van Amerongen A. Lateral flow (immuno)assay: its strengths, weaknesses, opportunities and threats. A literature survey. Anal Bioanal Chem. 2009;393(2):569–82.CrossRefPubMed
22.
Zurück zum Zitat Qian S, Haim H. A mathematical model of lateral flow bioreactions applied to sandwich assays. Anal Biochem. 2003;322(1):89–98.CrossRefPubMed Qian S, Haim H. A mathematical model of lateral flow bioreactions applied to sandwich assays. Anal Biochem. 2003;322(1):89–98.CrossRefPubMed
23.
Zurück zum Zitat Qian S, Haim H. Analysis of lateral flow biodetectors: competitive format. Anal Biochem. 2004;326(2):211–24.CrossRefPubMed Qian S, Haim H. Analysis of lateral flow biodetectors: competitive format. Anal Biochem. 2004;326(2):211–24.CrossRefPubMed
24.
Zurück zum Zitat Raphael C, Harley Y. Lateral flow immunoassay. New York City: Humana Press; 2008. Raphael C, Harley Y. Lateral flow immunoassay. New York City: Humana Press; 2008.
25.
Zurück zum Zitat Srivastava R, Cheng J, Wong D, Liu J. Using deep learning for robustness to parapapillary atrophy in optic disc segmentation. In: 2015 IEEE 12th international symposium on biomedical imaging; 2015. p. 768–71. Srivastava R, Cheng J, Wong D, Liu J. Using deep learning for robustness to parapapillary atrophy in optic disc segmentation. In: 2015 IEEE 12th international symposium on biomedical imaging; 2015. p. 768–71.
26.
Zurück zum Zitat Sumonphan E, Auephanwiriyakul S, Theera-Umpon N. Interpretation of nevirapine concentration from immunochromatographic strip test using support vector regression. In: Proceedings of 2008 IEEE international conference on mechatronics and automation; 2008. p. 633–7. Sumonphan E, Auephanwiriyakul S, Theera-Umpon N. Interpretation of nevirapine concentration from immunochromatographic strip test using support vector regression. In: Proceedings of 2008 IEEE international conference on mechatronics and automation; 2008. p. 633–7.
27.
Zurück zum Zitat Tanaka R, Yuhi T, Nagatani N, Endo T, Kerman K, Takamura Y. A novel enhancement assay for immunochromatographic test strips using gold nanoparticles. Anal Bioanal Chem. 2006;385(8):1414–20.CrossRefPubMed Tanaka R, Yuhi T, Nagatani N, Endo T, Kerman K, Takamura Y. A novel enhancement assay for immunochromatographic test strips using gold nanoparticles. Anal Bioanal Chem. 2006;385(8):1414–20.CrossRefPubMed
28.
Zurück zum Zitat Wei H, Dong Z. V4 neural network model for shape-based feature extraction and object discrimination. Cogn Comput. 2015;7(6):753–62.CrossRef Wei H, Dong Z. V4 neural network model for shape-based feature extraction and object discrimination. Cogn Comput. 2015;7(6):753–62.CrossRef
29.
Zurück zum Zitat Wei H, Li H. Shape description and recognition method inspired by the primary visual cortex. Cogn Comput. 2014;6(2):164–74.CrossRef Wei H, Li H. Shape description and recognition method inspired by the primary visual cortex. Cogn Comput. 2014;6(2):164–74.CrossRef
30.
Zurück zum Zitat Yager P, Edwards T, Fu E, Helton K, Nelson K, Tam MR, Weigl BH. Microfuidic diagnostic technologies for global public health. Nature. 2006;442:412–8.CrossRefPubMed Yager P, Edwards T, Fu E, Helton K, Nelson K, Tam MR, Weigl BH. Microfuidic diagnostic technologies for global public health. Nature. 2006;442:412–8.CrossRefPubMed
31.
Zurück zum Zitat Yang H, Wang Z, Shu H, Alsaadi FE, Hayat T. Almost sure \(H_{\infty }\) sliding mode control for nonlinear stochastic systems with Markovian switching and time-delays. Neurocomputing. 2016;175:392–400.CrossRef Yang H, Wang Z, Shu H, Alsaadi FE, Hayat T. Almost sure \(H_{\infty }\) sliding mode control for nonlinear stochastic systems with Markovian switching and time-delays. Neurocomputing. 2016;175:392–400.CrossRef
32.
Zurück zum Zitat Yu Y, Dong H, Wang Z, Ren W, Alsaadi FE. Design of non-fragile state estimators for discrete time-delayed neural networks with parameter uncertainties. Neurocomputing. 2016;182:18–24.CrossRef Yu Y, Dong H, Wang Z, Ren W, Alsaadi FE. Design of non-fragile state estimators for discrete time-delayed neural networks with parameter uncertainties. Neurocomputing. 2016;182:18–24.CrossRef
33.
Zurück zum Zitat Yu D, Deng L. Deep learning and its applications to signal and information processing. IEEE Signal Process Mag. 2011;28(1):145–54.CrossRef Yu D, Deng L. Deep learning and its applications to signal and information processing. IEEE Signal Process Mag. 2011;28(1):145–54.CrossRef
34.
Zurück zum Zitat Zeng N, Wang Z, Li Y, Du M, Liu X. Inference of nonlinear state-space models for sandwich-type lateral flow immunoassay using extended Kalman filtering. IEEE Trans Biomed Eng. 2011;58(7):1959–66.CrossRefPubMed Zeng N, Wang Z, Li Y, Du M, Liu X. Inference of nonlinear state-space models for sandwich-type lateral flow immunoassay using extended Kalman filtering. IEEE Trans Biomed Eng. 2011;58(7):1959–66.CrossRefPubMed
35.
Zurück zum Zitat Zeng N, Wang Z, Li Y, Du M, Liu X. A hybrid EKF and switching PSO algorithm for joint state and parameter estimation of lateral flow immunoassay models. IEEE/ACM Trans Comput Biol Bioinf. 2012;9(2):321–9.CrossRef Zeng N, Wang Z, Li Y, Du M, Liu X. A hybrid EKF and switching PSO algorithm for joint state and parameter estimation of lateral flow immunoassay models. IEEE/ACM Trans Comput Biol Bioinf. 2012;9(2):321–9.CrossRef
36.
Zurück zum Zitat Zeng N, Wang Z, Li Y, Du M, Liu X. Identification of nonlinear lateral flow immunoassay state-space models via particle filter approach. IEEE Trans Nanotechnol. 2012;11(2):321–7.CrossRef Zeng N, Wang Z, Li Y, Du M, Liu X. Identification of nonlinear lateral flow immunoassay state-space models via particle filter approach. IEEE Trans Nanotechnol. 2012;11(2):321–7.CrossRef
37.
Zurück zum Zitat Zeng N, Wang Z, Li Y, Du M. Cellular neural networks for gold immunochromatographic strip image segmentation. Lect Notes Comput Sci. 2012;7231:110–20.CrossRef Zeng N, Wang Z, Li Y, Du M. Cellular neural networks for gold immunochromatographic strip image segmentation. Lect Notes Comput Sci. 2012;7231:110–20.CrossRef
38.
Zurück zum Zitat Zeng N, Wang Z, Li Y, Du M, Cao J, Liu X. Time series modeling of nano-gold immunochromatographic assay via expectation maximization algorithm. IEEE Trans Biomed Eng. 2013;60(12):3418–24.CrossRefPubMed Zeng N, Wang Z, Li Y, Du M, Cao J, Liu X. Time series modeling of nano-gold immunochromatographic assay via expectation maximization algorithm. IEEE Trans Biomed Eng. 2013;60(12):3418–24.CrossRefPubMed
39.
Zurück zum Zitat Zeng N, Hung YS, Li Y, Du M. A novel switching local evolutionary PSO for quantitative analysis of lateral flow immunoassay. Expert Syst Appl. 2014;41(4):1708–15.CrossRef Zeng N, Hung YS, Li Y, Du M. A novel switching local evolutionary PSO for quantitative analysis of lateral flow immunoassay. Expert Syst Appl. 2014;41(4):1708–15.CrossRef
40.
Zurück zum Zitat Zeng N, Wang Z, Zineddin B, Li Y, Du M, Xiao L, Liu X, Young T. Image-based quantitative analysis of gold immunochromatographic strip via cellular neural network approach. IEEE Trans Med Imaging. 2014;33(5):1129–36.CrossRefPubMed Zeng N, Wang Z, Zineddin B, Li Y, Du M, Xiao L, Liu X, Young T. Image-based quantitative analysis of gold immunochromatographic strip via cellular neural network approach. IEEE Trans Med Imaging. 2014;33(5):1129–36.CrossRefPubMed
41.
Zurück zum Zitat Zeng N, Wang Z, Zhang H, Alsaadi Fuad E. A novel switching delayed PSO algorithm for estimating unknown parameters of lateral flow immunoassay. Cogn Comput. 2016;8(2):143–52. Zeng N, Wang Z, Zhang H, Alsaadi Fuad E. A novel switching delayed PSO algorithm for estimating unknown parameters of lateral flow immunoassay. Cogn Comput. 2016;8(2):143–52.
42.
Zurück zum Zitat Zhao J, Du C, Sun H, Liu X, Sun J. Biologically motivated model for outdoor scene classification. Cogn Comput. 2013;7(1):20–33.CrossRef Zhao J, Du C, Sun H, Liu X, Sun J. Biologically motivated model for outdoor scene classification. Cogn Comput. 2013;7(1):20–33.CrossRef
43.
Zurück zum Zitat Zineddin B, Wang Z, Shi Y, Li Y, Du M, Liu X. A multi-view approach to cDNA microarray analysis. Int J Comput Biol Drug Des. 2010;3(2):91–111.CrossRefPubMed Zineddin B, Wang Z, Shi Y, Li Y, Du M, Liu X. A multi-view approach to cDNA microarray analysis. Int J Comput Biol Drug Des. 2010;3(2):91–111.CrossRefPubMed
Metadaten
Titel
Deep Belief Networks for Quantitative Analysis of a Gold Immunochromatographic Strip
verfasst von
Nianyin Zeng
Zidong Wang
Hong Zhang
Weibo Liu
Fuad E. Alsaadi
Publikationsdatum
01.08.2016
Verlag
Springer US
Erschienen in
Cognitive Computation / Ausgabe 4/2016
Print ISSN: 1866-9956
Elektronische ISSN: 1866-9964
DOI
https://doi.org/10.1007/s12559-016-9404-x

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