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Erschienen in: Colloid and Polymer Science 9/2010

01.06.2010 | Original Contribution

Design of polymeric nanoparticles for the encapsulation of monoacylglycerol

verfasst von: Paramaporn Chiewpattanakul, Rudy Covis, Régis Vanderesse, Benjamas Thanomsub, Emmanuelle Marie, Alain Durand

Erschienen in: Colloid and Polymer Science | Ausgabe 9/2010

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Abstract

Dextran-covered nanoparticles were produced by two different processes: emulsion/solvent evaporation and nanoprecipitation for the encapsulation of monomyristin. The inner core was formed by poly(lactic acid) or by a hydrophobically modified dextran (carrying n-decyl chains). According to the core materials and/or to the process, the average size of nanoparticles as well as the extent of aggregate formation was modulated. It was shown that the presence of monomyristin induced significant modifications on the characteristics of the resulting suspension (size and aggregate formation). Varying the matrix polymer as well as the amount of monomyristin in the feed allowed obtaining nanoparticles with convenient size. The use of hydrophobically modified dextran as the matrix material appeared promising.

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Metadaten
Titel
Design of polymeric nanoparticles for the encapsulation of monoacylglycerol
verfasst von
Paramaporn Chiewpattanakul
Rudy Covis
Régis Vanderesse
Benjamas Thanomsub
Emmanuelle Marie
Alain Durand
Publikationsdatum
01.06.2010
Verlag
Springer-Verlag
Erschienen in
Colloid and Polymer Science / Ausgabe 9/2010
Print ISSN: 0303-402X
Elektronische ISSN: 1435-1536
DOI
https://doi.org/10.1007/s00396-010-2216-8

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