nach oben

Polymer Bulletin

Erschienen in:

27.11.2022 | ORIGINAL PAPER

Effect of additives on fabrication and properties of hydroxypropyl methylcellulose-based hydrogels

verfasst von: Ha N. Giang, Anh T. K. Le, Tuan N. A. Huynh, Thanh Khoa Phung, Wataru Sakai

Erschienen in: Polymer Bulletin | Ausgabe 10/2023

Einloggen

Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.

search-config

KI-gestützte Suche

Aus

Abstract

Hydrogel materials based on bio-degradable polymers have received a lot of interest owing to many potential applications. In this study, hydroxypropyl methylcellulose (HPMC) as a based polymer was cross-linked using 5 wt% of non-toxic citric acid. Polyethylene glycol (PEG) and glycerol were used as gelation accelerants. The effect of reaction temperature on the ability to cross-link the matrix was investigated using differential scanning calorimetry (DSC), thermogravimetric (TGA), and dynamic mechanical analysis (DMA). The cross-linking process could not be observed using DSC or TGA. However, the sample with PEG and glycerol exhibited the highest increase of storage modulus in DMA measurement. A completely gelled state (100% gel fraction) could be obtained in all sample types at the temperature of 140 °C for 10 h. The addition of PEG significantly improved the gel fraction of HPMC-based hydrogel. With a higher concentration of PEG, the increase of C = O groups which were a result of the esterification of citric acid and HPMC molecule was confirmed by Fourier transform infrared spectroscopy (FTIR). The sample with 1 wt% of PEG showed the highest methylene blue adsorption.

Vorheriger Artikel Activated porous carbon derived from ethynyl phenyl azo phenol-biphenylene resin for high-performance supercapacitor

Nächster Artikel Functionalization of the magnetic chitosan support with dipyridylamine as a nitrogen-rich pincer ligand for Pd immobilization and investigation of catalytic efficiency in Sonogashira coupling

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

über 102.000 Bücher
über 537 Zeitschriften

aus folgenden Fachgebieten:

Automobil + Motoren
Bauwesen + Immobilien
Business IT + Informatik
Elektrotechnik + Elektronik
Energie + Nachhaltigkeit
Finance + Banking
Management + Führung
Marketing + Vertrieb
Maschinenbau + Werkstoffe
Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Jetzt informieren

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

über 67.000 Bücher
über 390 Zeitschriften

aus folgenden Fachgebieten:

Automobil + Motoren
Bauwesen + Immobilien
Business IT + Informatik
Elektrotechnik + Elektronik
Energie + Nachhaltigkeit
Maschinenbau + Werkstoffe

Jetzt Wissensvorsprung sichern!

Jetzt informieren

Nur mit Berechtigung zugänglich

Guilherme MR, Aouada FA, Fajardo AR, Martins AF, Paulino AT, Davi MFT et al (2015) Superabsorbent hydrogels based on polysaccharides for application in agriculture as soil conditioner and nutrient carrier: A review. Eur Polymer J 72:365–385. https://doi.org/10.1016/j.eurpolymj.2015.04.017CrossRef

Hamidi M, Azadi A, Rafiei P (2008) Hydrogel nanoparticles in drug delivery. Adv Drug Deliv Rev 60(15):1638–1649. https://doi.org/10.1016/j.addr.2008.08.002CrossRefPubMed

Sikareepaisan P, Ruktanonchai U, Supaphol P (2011) Preparation and characterization of asiaticoside-loaded alginate films and their potential for use as effectual wound dressings. Carbohyd Polym 83(4):1457–1469. https://doi.org/10.1016/j.carbpol.2010.09.048CrossRef

Hassan CM, Peppas NA. (2000) Structure and Applications of Poly(vinyl alcohol) Hydrogels Produced by Conventional Crosslinking or by Freezing/Thawing Methods. Biopolymers · PVA Hydrogels, Anionic Polymerisation Nanocomposites. Berlin, Heidelberg: Springer Berlin Heidelberg. p. 37–65.

Sennakesavan G, Mostakhdemin M, Dkhar LK, Seyfoddin A, Fatihhi SJ (2020) Acrylic acid/acrylamide based hydrogels and its properties - a review. Polym Degrad Stab 180:109308. https://doi.org/10.1016/j.polymdegradstab.2020.109308CrossRef

Ambrosio L, Demitri C, Sannino A (2011) 2 - Superabsorbent cellulose-based hydrogels for biomedical applications. In: Rimmer S (ed) Biomedical Hydrogels. Woodhead Publishing, pp 25–50CrossRef

Chang C, Zhang L (2011) Cellulose-based hydrogels: present status and application prospects. Carbohyd Polym 84(1):40–53. https://doi.org/10.1016/j.carbpol.2010.12.023CrossRef

Zainal SH, Mohd NH, Suhaili N, Anuar FH, Lazim AM, Othaman R (2021) Preparation of cellulose-based hydrogel: a review. J Market Res 10:935–952. https://doi.org/10.1016/j.jmrt.2020.12.012CrossRef

Ciolacu DE, Suflet DM. (2018) 11 - Cellulose-Based Hydrogels for Medical/Pharmaceutical Applications. In: Popa V, Volf I, editors. Biomass as Renewable Raw Material to Obtain Bioproducts of High-Tech Value. Elsevier. p. 401–39.

10.

te Nijenhuis K (2007) On the nature of crosslinks in thermoreversible gels. Polym Bull 58(1):27–42. https://doi.org/10.1007/s00289-006-0610-7CrossRef

11.

Vinatier C, Magne D, Moreau A, Gauthier O, Malard O, Vignes-Colombeix C et al (2007) Engineering cartilage with human nasal chondrocytes and a silanized hydroxypropyl methylcellulose hydrogel. J Biomed Mater Res, Part A 80A(1):66–74. https://doi.org/10.1002/jbm.a.30867CrossRef

12.

Kono H, Fujita S (2012) Biodegradable superabsorbent hydrogels derived from cellulose by esterification crosslinking with 1,2,3,4-butanetetracarboxylic dianhydride. Carbohyd Polym 87(4):2582–2588. https://doi.org/10.1016/j.carbpol.2011.11.045CrossRef

13.

Yoshimura T, Matsuo K, Fujioka R (2006) Novel biodegradable superabsorbent hydrogels derived from cotton cellulose and succinic anhydride: Synthesis and characterization. J Appl Polym Sci 99(6):3251–3256. https://doi.org/10.1002/app.22794CrossRef

14.

Sannino A, Madaghiele M, Conversano F, Mele G, Maffezzoli A, Netti PA et al (2004) Cellulose derivative−hyaluronic acid-based microporous hydrogels cross-linked through divinyl sulfone (DVS) to modulate equilibrium sorption capacity and network stability. Biomacromol 5(1):92–96. https://doi.org/10.1021/bm0341881CrossRef

15.

Udoetok IA, Dimmick RM, Wilson LD, Headley JV (2016) Adsorption properties of cross-linked cellulose-epichlorohydrin polymers in aqueous solution. Carbohyd Polym 136:329–340. https://doi.org/10.1016/j.carbpol.2015.09.032CrossRef

16.

Demitri C, Del Sole R, Scalera F, Sannino A, Vasapollo G, Maffezzoli A et al (2008) Novel superabsorbent cellulose-based hydrogels crosslinked with citric acid. J Appl Polym Sci 110(4):2453–2460. https://doi.org/10.1002/app.28660CrossRef

17.

Capanema NSV, Mansur AAP, de Jesus AC, Carvalho SM, de Oliveira LC, Mansur HS (2018) Superabsorbent crosslinked carboxymethyl cellulose-PEG hydrogels for potential wound dressing applications. Int J Biol Macromol 106:1218–1234. https://doi.org/10.1016/j.ijbiomac.2017.08.124CrossRefPubMed

18.

Burdock GA (2007) Safety assessment of hydroxypropyl methylcellulose as a food ingredient. Food Chem Toxicol 45(12):2341–2351. https://doi.org/10.1016/j.fct.2007.07.011CrossRefPubMed

19.

Kaur G, Grewal J, Jyoti K, Jain UK, Chandra R, Madan J (2018) Oral controlled and sustained drug delivery systems. Drug Targeting and Stimuli Sensitive Drug Delivery Systems. Elsevier, pp 567–626. https://doi.org/10.1016/B978-0-12-813689-8.00015-XCrossRef

20.

Joshi SC (2011) Sol-gel behavior of hydroxypropyl methylcellulose (HPMC) in ionic media including drug release. Materials (Basel) 4(10):1861–1905. https://doi.org/10.3390/ma4101861CrossRefPubMedPubMedCentral

21.

Perez-Robles S, Carotenuto C, Minale M (2022) HPMC Hydrogel formation mechanisms unveiled by the evaluation of the activation energy. Polymers. https://doi.org/10.3390/polym14030635CrossRefPubMedPubMedCentral

22.

Nie S, Pan W, Li X, Wu X (2004) The effect of citric acid added to hydroxypropyl methylcellulose (HPMC) matrix tablets on the release profile of vinpocetine. Drug Dev Ind Pharm 30(6):627–635. https://doi.org/10.1081/DDC-120037664CrossRefPubMed

23.

Marani PL, Bloisi GD, Petri DFS (2015) Hydroxypropylmethyl cellulose films crosslinked with citric acid for control release of nicotine. Cellulose 22(6):3907–3918. https://doi.org/10.1007/s10570-015-0757-1CrossRef

24.

Lagergren SK (1898) About the theory of so-called adsorption of Soluble substances. Sven Vetenskapsakad Handingarl 24:1–39

25.

Gómez-Carracedo A, Alvarez-Lorenzo C, Gómez-Amoza JL, Concheiro A (2003) Chemical structure and glass transition temperature of non-ionic cellulose ethers. J Therm Anal Calorim 73(2):587–596. https://doi.org/10.1023/A:1025434314396CrossRef

26.

Akinosho H, Hawkins S, Wicker L (2013) Hydroxypropyl methylcellulose substituent analysis and rheological properties. Carbohyd Polym 98(1):276–281. https://doi.org/10.1016/j.carbpol.2013.05.081CrossRef

27.

Bashir S, Zafar N, Lebaz N, Mahmood A, Elaissari A (2020) Hydroxypropyl methylcellulose-based hydrogel copolymeric for controlled delivery of galantamine hydrobromide in dementia. Processes 8(11):1350. https://doi.org/10.3390/pr8111350CrossRef

28.

Wang J, Guo X (2020) Adsorption kinetic models: physical meanings, applications, and solving methods. J Hazard Mater 390:122156. https://doi.org/10.1016/j.jhazmat.2020.122156CrossRefPubMed

29.

Uliniuc A, Hamaide T, Popa M, Băcăiță S (2013) Modified starch-based hydrogels cross-linked with citric acid and their use as drug delivery systems for levofloxacin. Soft Mater 11(4):483–493. https://doi.org/10.1080/1539445X.2012.710698CrossRef

30.

Xie X, Liu Q (2004) Development and physicochemical characterization of new resistant citrate starch from different corn Starches. Starch - Stärke 56(8):364–370. https://doi.org/10.1002/star.200300261CrossRef

Titel: Effect of additives on fabrication and properties of hydroxypropyl methylcellulose-based hydrogels
verfasst von: Ha N. Giang
Anh T. K. Le
Tuan N. A. Huynh
Thanh Khoa Phung
Wataru Sakai
Publikationsdatum: 27.11.2022
Verlag: Springer Berlin Heidelberg
Erschienen in: Polymer Bulletin / Ausgabe 10/2023
Print ISSN: 0170-0839
Elektronische ISSN: 1436-2449
DOI: https://doi.org/10.1007/s00289-022-04610-7

Premium Partner

Marktübersichten

Die im Laufe eines Jahres in der „adhäsion“ veröffentlichten Marktübersichten helfen Anwendern verschiedenster Branchen, sich einen gezielten Überblick über Lieferantenangebote zu verschaffen.

Zur Marktübersicht

Springer Professional

Abstract

Bitte loggen Sie sich ein, um Zugang zu Ihrer Lizenz zu erhalten.

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Wirtschaft+Technik"

Springer Professional "Technik"

Weitere Artikel der Ausgabe 10/2023

Poly(acrylamide-co-acrylic acid)-based gel polymer electrolytes incorporated with sodium iodide for dye-sensitized solar cells (DSSCs)

Electrical conductivity of carbon ash surface immersed with nanoparticles (Co3O4-Cr2O3) for spectroscopic selective surfaces

Fabrication of conductive hybrid scaffold based on polyaniline/polyvinyl alcohol–chitosan nanoparticles for skin tissue engineering application

A sandwich electrospun nanofibers/Tragacanth hydrogel composite containing Aloe vera extract and silver sulfadiazine as a wound dressing

Use of Ricinus communis shredded material as filler in rotational molded parts to improve the bio-disintegration behavior

Synthesis of copper oxide nanoparticles embedded in porous chitosan membrane for photodegradation of organic dyes

Premium Partner

Marktübersichten