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Polymer Bulletin
Erschienen in: Polymer Bulletin 11/2013

01.11.2013 | Original Paper

Electrospinning of polyvinylalcohol–polycaprolactone composite scaffolds for tissue engineering applications

verfasst von: Subramanian Uma Maheshwari, Samuel Vasanth Kumar, Naveen Nagiah, Tiruchirapally Sivagnanam Uma

Erschienen in: Polymer Bulletin | Ausgabe 11/2013

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Abstract

Random nanofibrous composite scaffolds of PVA/PCL bilayer were fabricated by electrospinning method. The bilayer nanofibrous scaffolds were subjected to detailed structural, morphological, chemical, and thermal analysis using XRD, SEM, FTIR, and DSC. Morphological investigations revealed that the prepared nanofibers have uniform morphology and the average fiber diameters for bilayer samples A, B, and C are 203, 252, and 244 nm, respectively. The obtained scaffolds have a porous structure with porosity of 77, 89.2, and 78.3 % for bilayer samples A, B, and C, respectively. FTIR analysis ensured complete evaporation of solvent and formation of non-interactive bilayers. Biocompatibility of the membranes was investigated by studying the adhesion of mouse NIH 3T3 fibroblasts for 72 h, and its enhanced adhesion and proliferation proved its mettle as a potential scaffold for tissue engineering applications.
Vorheriger Artikel Kinetic effects of silica nanoparticles on thermal and radiation stability of polyolefins
Nächster Artikel Electrochemical properties of poly(4,4′-diaminodiphenyl sulfone) as a cathode material of lithium secondary batteries

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Metadaten
Titel
Electrospinning of polyvinylalcohol–polycaprolactone composite scaffolds for tissue engineering applications
verfasst von
Subramanian Uma Maheshwari
Samuel Vasanth Kumar
Naveen Nagiah
Tiruchirapally Sivagnanam Uma
Publikationsdatum
01.11.2013
Verlag
Springer Berlin Heidelberg
Erschienen in
Polymer Bulletin / Ausgabe 11/2013
Print ISSN: 0170-0839
Elektronische ISSN: 1436-2449
DOI
https://doi.org/10.1007/s00289-013-1002-4

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