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Erschienen in: Fibers and Polymers 4/2024

27.02.2024 | Regular Article

Exploring the Role of Ag Nanoparticle Distribution in Novel pH-Sensitive Nanofibers Containing Hyaluronic Acid for Enhanced Wound Healing with Sustained Curcumin Release

verfasst von: Zahra Sayyar, Mahsa Khadem Sadigh

Erschienen in: Fibers and Polymers | Ausgabe 4/2024

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Abstract

The use of nanofiber patches has received considerable attention as a promising solution for overcoming challenges in drug delivery. In this study, silver nanoparticles (Ag NPs) were incorporated in chitosan (CS), hyaluronic acid (HYA), and polyvinyl alcohol (PVA) to form nanofibers (namely, the CS/HYA/PVA-Ag nanofiber) for the controllable release of curcumin (CUR). The CUR release from the CS/HYA/PVA-Ag nanofibers consistently happened sustainably. Therefore, the prepared CS/HYA/PVA-Ag nanofibers show great promise in terms of their ability to expand the field of pH-dependent transdermal drug delivery (TDD) and sustainably release drugs. Additionally, the scratch assay results of these nanofibers further support their potential applications in wound healing.

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Metadaten
Titel
Exploring the Role of Ag Nanoparticle Distribution in Novel pH-Sensitive Nanofibers Containing Hyaluronic Acid for Enhanced Wound Healing with Sustained Curcumin Release
verfasst von
Zahra Sayyar
Mahsa Khadem Sadigh
Publikationsdatum
27.02.2024
Verlag
The Korean Fiber Society
Erschienen in
Fibers and Polymers / Ausgabe 4/2024
Print ISSN: 1229-9197
Elektronische ISSN: 1875-0052
DOI
https://doi.org/10.1007/s12221-024-00509-4

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