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2018 | OriginalPaper | Buchkapitel

1. Functional Micro-/Nanomaterials for Imaging Technology

verfasst von : Waner Chen, Wei Ma, Chunpeng Zou, Yan Yang, Gaoyi Yang, Li Liu, Zhe Liu

Erschienen in: Advances in Functional Micro-/Nanoimaging Probes

Verlag: Springer Singapore

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Abstract

Functional micro-/nanomaterials, in particular, micro-/nanoimaging probes, have emerged as a hot topic in terms of both basic research and biomedical applications. More importantly, innovations and clinical translations of advanced imaging probes have substantially revolutionalized diagnostic techniques and therapy strategies addressing critical diseases. Therefore, this chapter presents a comprehensive description of the development history of biomedical imaging technology over the past decades and discusses various types of imaging probes corresponding to versatile imaging modalities.

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Literatur
1.
Zurück zum Zitat Goodspeed, A.W.: Experiments on the Roentgen X-rays. Science 4, 236–237 (1896)CrossRef Goodspeed, A.W.: Experiments on the Roentgen X-rays. Science 4, 236–237 (1896)CrossRef
2.
Zurück zum Zitat Weissleder, R.: Molecular imaging: exploring the next frontier. Radiology 212, 609–614 (1999)CrossRef Weissleder, R.: Molecular imaging: exploring the next frontier. Radiology 212, 609–614 (1999)CrossRef
3.
Zurück zum Zitat Massoud, T.F., Gambhir, S.S.: Integrating noninvasive molecular imaging into molecular medicine: an evolving paradigm. Trends Mol. Med. 13, 183–191 (2007)CrossRef Massoud, T.F., Gambhir, S.S.: Integrating noninvasive molecular imaging into molecular medicine: an evolving paradigm. Trends Mol. Med. 13, 183–191 (2007)CrossRef
4.
Zurück zum Zitat Padmanabhan, P., Kumar, A., Kumar, S., Chaudhary, R.K., Gulyas, B.: Nanoparticles in practice for molecular-imaging applications: an overview. Acta Biomater. 41, 1 (2016)CrossRef Padmanabhan, P., Kumar, A., Kumar, S., Chaudhary, R.K., Gulyas, B.: Nanoparticles in practice for molecular-imaging applications: an overview. Acta Biomater. 41, 1 (2016)CrossRef
5.
Zurück zum Zitat Weissleder, R., Pittet, M.J.: Imaging in the era of molecular oncology. Nature 452, 580–589 (2008)CrossRef Weissleder, R., Pittet, M.J.: Imaging in the era of molecular oncology. Nature 452, 580–589 (2008)CrossRef
6.
Zurück zum Zitat Appel, A.A., Anastasio, M.A., Larson, J.C., Brey, E.M.: Imaging challenges in biomaterials and tissue engineering. Biomaterials 34, 6615–6630 (2013)CrossRef Appel, A.A., Anastasio, M.A., Larson, J.C., Brey, E.M.: Imaging challenges in biomaterials and tissue engineering. Biomaterials 34, 6615–6630 (2013)CrossRef
7.
Zurück zum Zitat Lee, D.E., Koo, H., Sun, I.C., Ryu, J.H., Kim, K., Kwon, I.C.: Multifunctional nanoparticles for multimodal imaging and theragnosis. Chem. Soc. Rev. 41, 2656 (2012)CrossRef Lee, D.E., Koo, H., Sun, I.C., Ryu, J.H., Kim, K., Kwon, I.C.: Multifunctional nanoparticles for multimodal imaging and theragnosis. Chem. Soc. Rev. 41, 2656 (2012)CrossRef
8.
Zurück zum Zitat Lu, F.M., Yuan, Z.: PET/SPECT molecular imaging in clinical neuroscience: recent advances in the investigation of CNS diseases. Quant. Imaging Med. Surg. 5, 433–447 (2015) Lu, F.M., Yuan, Z.: PET/SPECT molecular imaging in clinical neuroscience: recent advances in the investigation of CNS diseases. Quant. Imaging Med. Surg. 5, 433–447 (2015)
9.
Zurück zum Zitat Trequesser, Q.L., Seznec, H., Delville, M.: Functionalized nanomaterials: their use as contrast agents in bioimaging: mono- and multimodal approaches. Nanotech. Rev. 2, 125–169 (2013)CrossRef Trequesser, Q.L., Seznec, H., Delville, M.: Functionalized nanomaterials: their use as contrast agents in bioimaging: mono- and multimodal approaches. Nanotech. Rev. 2, 125–169 (2013)CrossRef
10.
Zurück zum Zitat Herrling, P.L., Alex, M.M.D., Rudin, M.: Imaging in drug discovery and early clinical trials. J. Nucl. Med. 2006, 48 (1037) Herrling, P.L., Alex, M.M.D., Rudin, M.: Imaging in drug discovery and early clinical trials. J. Nucl. Med. 2006, 48 (1037)
11.
Zurück zum Zitat Baker, M.: Whole-animal imaging: the whole picture. Nature 463, 977–980 (2010)CrossRef Baker, M.: Whole-animal imaging: the whole picture. Nature 463, 977–980 (2010)CrossRef
12.
Zurück zum Zitat Suetens, P.: Fundamentals of Medical Imaging, 2nd edn. Cambridge University Press, New York, USA (2009)CrossRef Suetens, P.: Fundamentals of Medical Imaging, 2nd edn. Cambridge University Press, New York, USA (2009)CrossRef
13.
Zurück zum Zitat Smith, L., Kuncic, Z., Ostrikov, K., Kumar, S.: Nanoparticles in cancer imaging and therapy. J. Nanomater. 2012, 10 (2012)CrossRef Smith, L., Kuncic, Z., Ostrikov, K., Kumar, S.: Nanoparticles in cancer imaging and therapy. J. Nanomater. 2012, 10 (2012)CrossRef
14.
Zurück zum Zitat Chi, X., Huang, D., Zhao, Z., Zhou, Z., Yin, Z., Gao, J.: Nanoprobes for invitro, diagnostics of cancer and infectious diseases. Biomaterials 33, 189–206 (2012)CrossRef Chi, X., Huang, D., Zhao, Z., Zhou, Z., Yin, Z., Gao, J.: Nanoprobes for invitro, diagnostics of cancer and infectious diseases. Biomaterials 33, 189–206 (2012)CrossRef
15.
Zurück zum Zitat Li, K., Liu, B.: Polymer encapsulated conjugated polymer nanoparticles for fluorescence bioimaging. J. Mater. Chem. 22, 1257–1264 (2011)CrossRef Li, K., Liu, B.: Polymer encapsulated conjugated polymer nanoparticles for fluorescence bioimaging. J. Mater. Chem. 22, 1257–1264 (2011)CrossRef
16.
Zurück zum Zitat Mao, X., Xu, J., Cui, H.: Functional nanoparticles for magnetic resonance imaging. Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol. 8, 814–841 (2016)CrossRef Mao, X., Xu, J., Cui, H.: Functional nanoparticles for magnetic resonance imaging. Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol. 8, 814–841 (2016)CrossRef
17.
Zurück zum Zitat Hung, A.H., Duch, M.C., Parigi, G., Rotz, M.W., Manus, L.M., Mastarone, D.J.: Mechanisms of gadographene-mediated proton spin relaxation. J. Phys. Chem. C 117, 16263–16273 (2013)CrossRef Hung, A.H., Duch, M.C., Parigi, G., Rotz, M.W., Manus, L.M., Mastarone, D.J.: Mechanisms of gadographene-mediated proton spin relaxation. J. Phys. Chem. C 117, 16263–16273 (2013)CrossRef
18.
Zurück zum Zitat Matosziuk, L.M., Leibowitz, J.H., Heffern, M.C., Macrenaris, K.W., Ratner, M.A., Meade, T.J.: Structural optimization of Zn(II)-activated magnetic resonance imaging probes. Inorg. Chem. 52, 12250 (2013)CrossRef Matosziuk, L.M., Leibowitz, J.H., Heffern, M.C., Macrenaris, K.W., Ratner, M.A., Meade, T.J.: Structural optimization of Zn(II)-activated magnetic resonance imaging probes. Inorg. Chem. 52, 12250 (2013)CrossRef
19.
Zurück zum Zitat Jacobs, R.E., Papan, C., Ruffins, S., Tyszka, J.M., Fraser, S.E.: MRI: Volumetric imaging for vital imaging and atlas construction. Nat. Rev. Mol. Cell Biol. 4(Suppl. 1), SS10 (2003) Jacobs, R.E., Papan, C., Ruffins, S., Tyszka, J.M., Fraser, S.E.: MRI: Volumetric imaging for vital imaging and atlas construction. Nat. Rev. Mol. Cell Biol. 4(Suppl. 1), SS10 (2003)
20.
Zurück zum Zitat Artemov, D.: Molecular magnetic resonance imaging with targeted contrast agents. J. Cell. Biochem. 90, 518–524 (2003)CrossRef Artemov, D.: Molecular magnetic resonance imaging with targeted contrast agents. J. Cell. Biochem. 90, 518–524 (2003)CrossRef
21.
Zurück zum Zitat Potter, K.: Magnetic resonance microscopy approaches to molecular imaging: sensitivity vs. specificity. J. Cell. Biochem. 87(Suppl. 39), 147–153 (2002)CrossRef Potter, K.: Magnetic resonance microscopy approaches to molecular imaging: sensitivity vs. specificity. J. Cell. Biochem. 87(Suppl. 39), 147–153 (2002)CrossRef
22.
Zurück zum Zitat Aime, S., Cabella, C., Colombatto, S., Geninatti, C.S., Gianolio, E., Maggioni, F.: Insights into the use of paramagnetic Gd(III) complexes in MR-molecular imaging investigations. J. Magn. Reson. Imaging 16, 394–406 (2002)CrossRef Aime, S., Cabella, C., Colombatto, S., Geninatti, C.S., Gianolio, E., Maggioni, F.: Insights into the use of paramagnetic Gd(III) complexes in MR-molecular imaging investigations. J. Magn. Reson. Imaging 16, 394–406 (2002)CrossRef
23.
Zurück zum Zitat Caravan, P., Ellison, J.J., Mcmurry, T.J., Lauffer, R.B.: Gadolinium (III) chelates as MRI contrast agents: structure, dynamics, and applications. Cheminform 99, 2293 (1999) Caravan, P., Ellison, J.J., Mcmurry, T.J., Lauffer, R.B.: Gadolinium (III) chelates as MRI contrast agents: structure, dynamics, and applications. Cheminform 99, 2293 (1999)
24.
Zurück zum Zitat Kabalka, G.W., Davis, M.A., Moss, T.H., Buonocore, E., Hubner, K., Holmberg, E.: Gadolinium-labeled liposomes containing various amphiphilic Gd-DTPA derivatives: targeted MRI contrast enhancement agents for the liver. Magn. Reson. Med. 19, 406–415 (1991)CrossRef Kabalka, G.W., Davis, M.A., Moss, T.H., Buonocore, E., Hubner, K., Holmberg, E.: Gadolinium-labeled liposomes containing various amphiphilic Gd-DTPA derivatives: targeted MRI contrast enhancement agents for the liver. Magn. Reson. Med. 19, 406–415 (1991)CrossRef
25.
Zurück zum Zitat Guenoun, J., Koning, G.A., Doeswijk, G., Bosman, L., Wielopolski, P.A., Krestin, G.P.: Cationic Gd-DTPA liposomes for highly efficient labeling of mesenchymal stem cells and cell tracking with MRI. Cell Transplant. 21, 191–205 (2012)CrossRef Guenoun, J., Koning, G.A., Doeswijk, G., Bosman, L., Wielopolski, P.A., Krestin, G.P.: Cationic Gd-DTPA liposomes for highly efficient labeling of mesenchymal stem cells and cell tracking with MRI. Cell Transplant. 21, 191–205 (2012)CrossRef
26.
Zurück zum Zitat Cheng, Z., Thorek, D.L.J., Tsourkas, A.: Gd-conjugated dendrimer nanoclusters as a tumor-targeted T1 magnetic resonance imaging contrast agent. Angew. Chem. 49, 346–350 (2010)CrossRef Cheng, Z., Thorek, D.L.J., Tsourkas, A.: Gd-conjugated dendrimer nanoclusters as a tumor-targeted T1 magnetic resonance imaging contrast agent. Angew. Chem. 49, 346–350 (2010)CrossRef
27.
Zurück zum Zitat Huang, C.H., Nwe, K., Al, Z.A., Brechbiel, M.W., Tsourkas, A.: Biodegradable polydisulfide dendrimer nanoclusters as MRI contrast agents. ACS Nano 6, 9416 (2012)CrossRef Huang, C.H., Nwe, K., Al, Z.A., Brechbiel, M.W., Tsourkas, A.: Biodegradable polydisulfide dendrimer nanoclusters as MRI contrast agents. ACS Nano 6, 9416 (2012)CrossRef
28.
Zurück zum Zitat Yang, H., Santra, S., Walter, G., Holloway, P.: Gd(III)-functionalized fluorescent quantum dots as multimodal imaging probes. Adv. Mater. 18, 2890–2894 (2006)CrossRef Yang, H., Santra, S., Walter, G., Holloway, P.: Gd(III)-functionalized fluorescent quantum dots as multimodal imaging probes. Adv. Mater. 18, 2890–2894 (2006)CrossRef
29.
Zurück zum Zitat Yang, W., Guo, W., Gong, X., Zhang, B., Wang, S., Chen, N.: Facile synthesis of Gd-Cu-In-S/ZnS bimodal quantum dots with optimized properties for tumor targeted fluorescence/mr in vivo imaging. ACS Appl. Mater. Interfaces 7, 18759–18768 (2015)CrossRef Yang, W., Guo, W., Gong, X., Zhang, B., Wang, S., Chen, N.: Facile synthesis of Gd-Cu-In-S/ZnS bimodal quantum dots with optimized properties for tumor targeted fluorescence/mr in vivo imaging. ACS Appl. Mater. Interfaces 7, 18759–18768 (2015)CrossRef
30.
Zurück zum Zitat Vivero-Escoto, J.L., Taylor-Pashow, K.M.L., Huxford, R.C., Della Rocca, J., Okoruwa, C., An, H.: Multifunctional mesoporous silica nanospheres with cleavable Gd(III) chelates as mri contrast agents: synthesis, characterization, target-specificity and renal clearance. Small 7, 3519–3528 (2011)CrossRef Vivero-Escoto, J.L., Taylor-Pashow, K.M.L., Huxford, R.C., Della Rocca, J., Okoruwa, C., An, H.: Multifunctional mesoporous silica nanospheres with cleavable Gd(III) chelates as mri contrast agents: synthesis, characterization, target-specificity and renal clearance. Small 7, 3519–3528 (2011)CrossRef
31.
Zurück zum Zitat Huang, C.C., Tsai, C.Y., Sheu, H.S., Chuang, K.Y., Su, C.H., Jeng, U.S.: Enhancing transversal relaxation for magnetite nanoparticles in mr imaging using Gd3+-chelated mesoporous silica shells. ACS Nano 5, 3905–3916 (2011)CrossRef Huang, C.C., Tsai, C.Y., Sheu, H.S., Chuang, K.Y., Su, C.H., Jeng, U.S.: Enhancing transversal relaxation for magnetite nanoparticles in mr imaging using Gd3+-chelated mesoporous silica shells. ACS Nano 5, 3905–3916 (2011)CrossRef
32.
Zurück zum Zitat Ghaghada, K.B., Ravoori, M., Sabapathy, D., Bankson, J., Kundra, V., Annapragada, A.: New dual mode gadolinium nanoparticle contrast agent for magnetic resonance imaging. PLoS ONE 4, e7628 (2009)CrossRef Ghaghada, K.B., Ravoori, M., Sabapathy, D., Bankson, J., Kundra, V., Annapragada, A.: New dual mode gadolinium nanoparticle contrast agent for magnetic resonance imaging. PLoS ONE 4, e7628 (2009)CrossRef
33.
Zurück zum Zitat Lu, J., Ma, S., Sun, J., Xia, C., Liu, C., Wang, Z.: Manganese ferrite nanoparticle micellar nanocomposites as MRI contrast agent for liver imaging. Biomaterials 30, 2919 (2009)CrossRef Lu, J., Ma, S., Sun, J., Xia, C., Liu, C., Wang, Z.: Manganese ferrite nanoparticle micellar nanocomposites as MRI contrast agent for liver imaging. Biomaterials 30, 2919 (2009)CrossRef
34.
Zurück zum Zitat Cassidy, P.J., Radda, G.K.: Molecular imaging perspectives. J. R. Soc. Interface 2, 133 (2005)CrossRef Cassidy, P.J., Radda, G.K.: Molecular imaging perspectives. J. R. Soc. Interface 2, 133 (2005)CrossRef
35.
Zurück zum Zitat Babes, L., Denizot, B., Tanguy, G., Le, J.J., Jallet, P.: Synthesis of iron oxide nanoparticles used as MRI contrast agents: a parametric study. J. Colloid Interface Sci. 212, 474 (1999)CrossRef Babes, L., Denizot, B., Tanguy, G., Le, J.J., Jallet, P.: Synthesis of iron oxide nanoparticles used as MRI contrast agents: a parametric study. J. Colloid Interface Sci. 212, 474 (1999)CrossRef
36.
Zurück zum Zitat Gramiak, R., Shah, P.M.: Echocardiography of the aortic root. Invest. Radiol. 3, 356–366 (1968)CrossRef Gramiak, R., Shah, P.M.: Echocardiography of the aortic root. Invest. Radiol. 3, 356–366 (1968)CrossRef
37.
Zurück zum Zitat Feinstein, S.B., Cheirif, J., Tencate, F.J., Silverman, P.R., Heidenreich, P.A., Dick, C., Desir, R.M., Armstrong, W.F., Quinones, M.A., Shah, P.M.: Safety and efficacy of a new transpulmonary ultrasound contrast agent: initial multicenter clinical results. J. Am. Coll. Cardiol. 16, 316–324 (1990)CrossRef Feinstein, S.B., Cheirif, J., Tencate, F.J., Silverman, P.R., Heidenreich, P.A., Dick, C., Desir, R.M., Armstrong, W.F., Quinones, M.A., Shah, P.M.: Safety and efficacy of a new transpulmonary ultrasound contrast agent: initial multicenter clinical results. J. Am. Coll. Cardiol. 16, 316–324 (1990)CrossRef
38.
Zurück zum Zitat Kaneko, O.F., Willmann, J.K.: Ultrasound for molecular imaging and therapy in cancer. Quant. Imaging Med. Surg. 2, 87–97 (2012) Kaneko, O.F., Willmann, J.K.: Ultrasound for molecular imaging and therapy in cancer. Quant. Imaging Med. Surg. 2, 87–97 (2012)
39.
Zurück zum Zitat Appis, A.W., Tracy, M.J., Feinstein, S.B.: Update on the safety and efficacy of commercial ultrasound contrast agents in cardiac applications. Echo Res. Pract. 2, R55–R62 (2015)CrossRef Appis, A.W., Tracy, M.J., Feinstein, S.B.: Update on the safety and efficacy of commercial ultrasound contrast agents in cardiac applications. Echo Res. Pract. 2, R55–R62 (2015)CrossRef
40.
Zurück zum Zitat Unger, E., Porter, T., Lindner, J., Grayburn, P.: Cardiovascular drug delivery with ultrasound and microbubbles. Adv. Drug Deliv. Rev. 72, 110–126 (2014)CrossRef Unger, E., Porter, T., Lindner, J., Grayburn, P.: Cardiovascular drug delivery with ultrasound and microbubbles. Adv. Drug Deliv. Rev. 72, 110–126 (2014)CrossRef
41.
Zurück zum Zitat Lindner, J.R.: Microbubbles in medical imaging: current applications and future directions. Nat. Rev. Drug Discov. 3, 527–532 (2004)CrossRef Lindner, J.R.: Microbubbles in medical imaging: current applications and future directions. Nat. Rev. Drug Discov. 3, 527–532 (2004)CrossRef
42.
Zurück zum Zitat Keller, M.W., Glasheen, W., Kaul, S.: Albunex: a safe and effective commercially produced agent for myocardial contrast echocardiography. J. Am. Soc. Echocardiogr. 2, 48–52 (1989)CrossRef Keller, M.W., Glasheen, W., Kaul, S.: Albunex: a safe and effective commercially produced agent for myocardial contrast echocardiography. J. Am. Soc. Echocardiogr. 2, 48–52 (1989)CrossRef
43.
Zurück zum Zitat Podell, S., Burrascano, C., Gaal, M., Golec, B., Maniquis, J., Mehlhaff, P.: Physical and biochemical stability of optison, an injectable ultrasound contrast agent. Biotech. Appl. Biochem. 30, 213–223 (1999) Podell, S., Burrascano, C., Gaal, M., Golec, B., Maniquis, J., Mehlhaff, P.: Physical and biochemical stability of optison, an injectable ultrasound contrast agent. Biotech. Appl. Biochem. 30, 213–223 (1999)
44.
Zurück zum Zitat Goertz, D.E., Jong, N.D., Steen, A.V.D.: Attenuation and size distribution measurements of definity™ and manipulated definity™ populations. Ultrasound Med. Biol. 33, 1376–1388 (2007)CrossRef Goertz, D.E., Jong, N.D., Steen, A.V.D.: Attenuation and size distribution measurements of definity™ and manipulated definity™ populations. Ultrasound Med. Biol. 33, 1376–1388 (2007)CrossRef
45.
Zurück zum Zitat Schneider, M.: Sonovue, a new ultrasound contrast agent. Eur. Radiol. 9(Suppl. 3), 347–348 (1999)CrossRef Schneider, M.: Sonovue, a new ultrasound contrast agent. Eur. Radiol. 9(Suppl. 3), 347–348 (1999)CrossRef
46.
Zurück zum Zitat Sontum, P.C.: Physicochemical characteristics of sonazoid, a new contrast agent for ultrasound imaging. Ultrasound Med. Biol. 34, 824–833 (2008)CrossRef Sontum, P.C.: Physicochemical characteristics of sonazoid, a new contrast agent for ultrasound imaging. Ultrasound Med. Biol. 34, 824–833 (2008)CrossRef
47.
Zurück zum Zitat Bhutani, M.S., Hoffman, B.J., Van, V.A., Hawes, R.H.: Contrast-enhanced endoscopic ultrasonography with galactose microparticles: SHU508 a (Levovist). Endoscopy 29, 635–639 (1997)CrossRef Bhutani, M.S., Hoffman, B.J., Van, V.A., Hawes, R.H.: Contrast-enhanced endoscopic ultrasonography with galactose microparticles: SHU508 a (Levovist). Endoscopy 29, 635–639 (1997)CrossRef
48.
Zurück zum Zitat Hoff, L., Sontum, P.C., Hoff, B.: Acoustic properties of shell-encapsulated, gas-filled ultrasound contrast agents. Ultrason. Symp. Proc. 2, 1441–1444 (1996) Hoff, L., Sontum, P.C., Hoff, B.: Acoustic properties of shell-encapsulated, gas-filled ultrasound contrast agents. Ultrason. Symp. Proc. 2, 1441–1444 (1996)
49.
Zurück zum Zitat Kiessling, F., Mertens, M.E., Grimm, J., Lammers, T.: Nanoparticles for imaging: top or flop? Radiology 273, 10 (2014)CrossRef Kiessling, F., Mertens, M.E., Grimm, J., Lammers, T.: Nanoparticles for imaging: top or flop? Radiology 273, 10 (2014)CrossRef
50.
Zurück zum Zitat Paefgen, V., Doleschel, D., Kiessling, F.: Evolution of contrast agents for ultrasound imaging and ultrasound-mediated drug delivery. Front. Pharm. 6, 197 (2015)CrossRef Paefgen, V., Doleschel, D., Kiessling, F.: Evolution of contrast agents for ultrasound imaging and ultrasound-mediated drug delivery. Front. Pharm. 6, 197 (2015)CrossRef
51.
Zurück zum Zitat Wei, S., Fu, N., Sun, Y., Yang, Z., Lei, L., Huang, P.: Targeted contrast-enhanced ultrasound imaging of angiogenesis in an orthotopic mouse tumor model of renal carcinoma. Ultrasound Med. Biol. 40, 1250–1259 (2014)CrossRef Wei, S., Fu, N., Sun, Y., Yang, Z., Lei, L., Huang, P.: Targeted contrast-enhanced ultrasound imaging of angiogenesis in an orthotopic mouse tumor model of renal carcinoma. Ultrasound Med. Biol. 40, 1250–1259 (2014)CrossRef
52.
Zurück zum Zitat Hu, Q., Wang, X.Y., Kang, L.K., Wei, H.M., Xu, C.M., Wang, T.: RGD-targeted ultrasound contrast agent for longitudinal assessment of Hep2 tumor angiogenesis in vivo. PLoS ONE 11, e0149075 (2016)CrossRef Hu, Q., Wang, X.Y., Kang, L.K., Wei, H.M., Xu, C.M., Wang, T.: RGD-targeted ultrasound contrast agent for longitudinal assessment of Hep2 tumor angiogenesis in vivo. PLoS ONE 11, e0149075 (2016)CrossRef
53.
Zurück zum Zitat Yuan, B., Rychak, J.: Tumor functional and molecular imaging utilizing ultrasound and ultrasound-mediated optical techniques. Am. J. Pathology 182, 305 (2013)CrossRef Yuan, B., Rychak, J.: Tumor functional and molecular imaging utilizing ultrasound and ultrasound-mediated optical techniques. Am. J. Pathology 182, 305 (2013)CrossRef
54.
Zurück zum Zitat Xu, J.S., Huang, J., Qin, R., Hinkle, G.H., Povoski, S.P., Martin, E.W.: Synthesizing and binding dual-mode poly (lactic-co-glycolic acid) (PLGA) nanobubbles for cancer targeting and imaging. Biomaterials 31, 1716–1722 (2009)CrossRef Xu, J.S., Huang, J., Qin, R., Hinkle, G.H., Povoski, S.P., Martin, E.W.: Synthesizing and binding dual-mode poly (lactic-co-glycolic acid) (PLGA) nanobubbles for cancer targeting and imaging. Biomaterials 31, 1716–1722 (2009)CrossRef
55.
Zurück zum Zitat Campbell, R.B.: Tumor physiology and delivery of nano pharmaceuticals. Anti-Cancer Agents Med. Chem. 6, 503–512 (2006)CrossRef Campbell, R.B.: Tumor physiology and delivery of nano pharmaceuticals. Anti-Cancer Agents Med. Chem. 6, 503–512 (2006)CrossRef
56.
Zurück zum Zitat Kang, E., Min, H.S., Lee, J.: Nanobubbles from gas-generating polymeric nanoparticles: ultrasound imaging of living subjects. Angew. Chem. 49, 524–528 (2010)CrossRef Kang, E., Min, H.S., Lee, J.: Nanobubbles from gas-generating polymeric nanoparticles: ultrasound imaging of living subjects. Angew. Chem. 49, 524–528 (2010)CrossRef
57.
Zurück zum Zitat Min, K.H., Min, H.S., Lee, H.J., Park, D.J., Yhee, J.Y., Kim, K.: pH-controlled gas-generating mineralized nanoparticles: a theranostic agent for ultrasound imaging and therapy of cancers. ACS Nano 9, 134–145 (2015)CrossRef Min, K.H., Min, H.S., Lee, H.J., Park, D.J., Yhee, J.Y., Kim, K.: pH-controlled gas-generating mineralized nanoparticles: a theranostic agent for ultrasound imaging and therapy of cancers. ACS Nano 9, 134–145 (2015)CrossRef
58.
Zurück zum Zitat Haller, C., Hizoh, I.: The cytotoxicity of iodinated radiocontrast agents on renal cells in vitro. Invest. Radiol. 39, 149 (2004)CrossRef Haller, C., Hizoh, I.: The cytotoxicity of iodinated radiocontrast agents on renal cells in vitro. Invest. Radiol. 39, 149 (2004)CrossRef
59.
Zurück zum Zitat Liu, Y., Ai, K., Lu, L.: Nanoparticulate X-ray computed tomography contrast agents: from design validation to in vivo applications. Acc. Chem. Res. 45, 1817–1827 (2012)CrossRef Liu, Y., Ai, K., Lu, L.: Nanoparticulate X-ray computed tomography contrast agents: from design validation to in vivo applications. Acc. Chem. Res. 45, 1817–1827 (2012)CrossRef
60.
Zurück zum Zitat Kong, W.H., Lee, W.J., Cui, Z.Y., Bae, K.H., Park, T.G., Kim, J.H.: Nanoparticulate carrier containing water-insoluble iodinated oil as a multifunctional contrast agent for computed tomography imaging. Biomaterials 28, 5555–5561 (2007)CrossRef Kong, W.H., Lee, W.J., Cui, Z.Y., Bae, K.H., Park, T.G., Kim, J.H.: Nanoparticulate carrier containing water-insoluble iodinated oil as a multifunctional contrast agent for computed tomography imaging. Biomaterials 28, 5555–5561 (2007)CrossRef
61.
Zurück zum Zitat Badea, C.T., Athreya, K.K., Espinosa, G., Clark, D., Ghafoori, A.P., Li, Y.: Computed tomography imaging of primary lung cancer in mice using a liposomal-iodinated contrast agent. PLoS ONE 7, e34496 (2012)CrossRef Badea, C.T., Athreya, K.K., Espinosa, G., Clark, D., Ghafoori, A.P., Li, Y.: Computed tomography imaging of primary lung cancer in mice using a liposomal-iodinated contrast agent. PLoS ONE 7, e34496 (2012)CrossRef
62.
Zurück zum Zitat Kim, D., Park, S., Lee, J.H., Jeong, Y.Y., Jon, S.: Antibiofouling polymer-coated gold nanoparticles as a contrast agent for in vivo X-ray computed tomography imaging. J. Am. Chem. Soc. 129, 7661 (2007)CrossRef Kim, D., Park, S., Lee, J.H., Jeong, Y.Y., Jon, S.: Antibiofouling polymer-coated gold nanoparticles as a contrast agent for in vivo X-ray computed tomography imaging. J. Am. Chem. Soc. 129, 7661 (2007)CrossRef
63.
Zurück zum Zitat Xiao, M., Nyagilo, J., Arora, V., Kulkarni, P., Xu, D., Sun, X.: Gold nanotags for combined multi-colored Raman spectroscopy and X-ray computed tomography. Nanotechnology 21, 035101 (2010)CrossRef Xiao, M., Nyagilo, J., Arora, V., Kulkarni, P., Xu, D., Sun, X.: Gold nanotags for combined multi-colored Raman spectroscopy and X-ray computed tomography. Nanotechnology 21, 035101 (2010)CrossRef
64.
Zurück zum Zitat Huo, D., Ding, J., Cui, Y.X., Xia, L.Y., Li, H., He, J.: X-ray CT and pneumonia inhibition properties of gold–silver nanoparticles for targeting MRSA, induced pneumonia. Biomaterials 35, 7032 (2014)CrossRef Huo, D., Ding, J., Cui, Y.X., Xia, L.Y., Li, H., He, J.: X-ray CT and pneumonia inhibition properties of gold–silver nanoparticles for targeting MRSA, induced pneumonia. Biomaterials 35, 7032 (2014)CrossRef
65.
Zurück zum Zitat Rabin, O., Manuel, P.J., Grimm, J., Wojtkiewicz, G., Weissleder, R.: An X-ray computed tomography imaging agent based on long-circulating bismuth sulphide nanoparticles. Nat. Mater. 5, 118–122 (2006)CrossRef Rabin, O., Manuel, P.J., Grimm, J., Wojtkiewicz, G., Weissleder, R.: An X-ray computed tomography imaging agent based on long-circulating bismuth sulphide nanoparticles. Nat. Mater. 5, 118–122 (2006)CrossRef
66.
Zurück zum Zitat Kinsella, J.M., Jimenez, R.E., Karmali, P.P., Rush, A.M., Kotamraju, V.R., Gianneschi, N.C.: X-ray computed tomography imaging of breast cancer by using targeted peptide-labeled bismuth sulfide nanoparticles. Angew. Chem. 50, 12308 (2011)CrossRef Kinsella, J.M., Jimenez, R.E., Karmali, P.P., Rush, A.M., Kotamraju, V.R., Gianneschi, N.C.: X-ray computed tomography imaging of breast cancer by using targeted peptide-labeled bismuth sulfide nanoparticles. Angew. Chem. 50, 12308 (2011)CrossRef
67.
Zurück zum Zitat Jin, Y., Li, Y., Ma, X., Zha, Z., Shi, L., Tian, J.: Encapsulating tantalum oxide into polypyrrole nanoparticles for X-ray ct/photoacoustic bimodal imaging-guided photothermal ablation of cancer. Biomaterials 35, 5795–5804 (2014)CrossRef Jin, Y., Li, Y., Ma, X., Zha, Z., Shi, L., Tian, J.: Encapsulating tantalum oxide into polypyrrole nanoparticles for X-ray ct/photoacoustic bimodal imaging-guided photothermal ablation of cancer. Biomaterials 35, 5795–5804 (2014)CrossRef
68.
Zurück zum Zitat Ai, K., Liu, Y., Liu, J., Yuan, Q., He, Y., Lu, L.: Large-scale synthesis of Bi2S3 nanodots as a contrast agent for in vivo X-ray computed tomography imaging. Adv. Mater. 23, 4886–4891 (2011)CrossRef Ai, K., Liu, Y., Liu, J., Yuan, Q., He, Y., Lu, L.: Large-scale synthesis of Bi2S3 nanodots as a contrast agent for in vivo X-ray computed tomography imaging. Adv. Mater. 23, 4886–4891 (2011)CrossRef
69.
Zurück zum Zitat Cherry, S.R.: The 2006 Henry N. Wagner lecture: of mice and men (and positrons)–advances in PET imaging technology. J. Nucl. Med. 47, 1735–1745 (2006) Cherry, S.R.: The 2006 Henry N. Wagner lecture: of mice and men (and positrons)–advances in PET imaging technology. J. Nucl. Med. 47, 1735–1745 (2006)
70.
Zurück zum Zitat Stockhofe, K., Postema, J.M., Schieferstein, H., Ross, T.L.: Radiolabeling of nanoparticles and polymers for pet imaging. Pharmaceuticals 7, 392–418 (2014)CrossRef Stockhofe, K., Postema, J.M., Schieferstein, H., Ross, T.L.: Radiolabeling of nanoparticles and polymers for pet imaging. Pharmaceuticals 7, 392–418 (2014)CrossRef
71.
Zurück zum Zitat Herth, M.M., Barz, M., Moderegger, D., Allmeroth, M., Jahn, M., Thews, O.: Radioactive labeling of defined HPMA-based polymeric structures using [18F]fetos for in vivo imaging by positron emission tomography. Biomacromol 10, 1697–1703 (2009)CrossRef Herth, M.M., Barz, M., Moderegger, D., Allmeroth, M., Jahn, M., Thews, O.: Radioactive labeling of defined HPMA-based polymeric structures using [18F]fetos for in vivo imaging by positron emission tomography. Biomacromol 10, 1697–1703 (2009)CrossRef
72.
Zurück zum Zitat Liu, Q., Sun, Y., Li, C., Zhou, J., Li, C., Yang, T.: 18F-labeled magnetic-upconversion nanophosphors via rare-earth cation-assisted ligand assembly. ACS Nano 5, 3146–3157 (2011)CrossRef Liu, Q., Sun, Y., Li, C., Zhou, J., Li, C., Yang, T.: 18F-labeled magnetic-upconversion nanophosphors via rare-earth cation-assisted ligand assembly. ACS Nano 5, 3146–3157 (2011)CrossRef
73.
Zurück zum Zitat Sang, B.L., Kim, H.L., Jeong, H.J., Lim, S.T., Sohn, M.H., Kim, D.W.: Mesoporous silica nanoparticle pretargeting for pet imaging based on a rapid bioorthogonal reaction in a living body. Angew. Chem. 52, 10549 (2013)CrossRef Sang, B.L., Kim, H.L., Jeong, H.J., Lim, S.T., Sohn, M.H., Kim, D.W.: Mesoporous silica nanoparticle pretargeting for pet imaging based on a rapid bioorthogonal reaction in a living body. Angew. Chem. 52, 10549 (2013)CrossRef
74.
Zurück zum Zitat Allmeroth, M., Moderegger, D., Gundel, D., Buchholz, H.G., Mohr, N., Koynov, K.: Pegylation of HPMA-based block copolymers enhances tumor accumulation in vivo: a quantitative study using radiolabeling and positron emission tomography. J. Control. Release 172, 77–85 (2013)CrossRef Allmeroth, M., Moderegger, D., Gundel, D., Buchholz, H.G., Mohr, N., Koynov, K.: Pegylation of HPMA-based block copolymers enhances tumor accumulation in vivo: a quantitative study using radiolabeling and positron emission tomography. J. Control. Release 172, 77–85 (2013)CrossRef
75.
Zurück zum Zitat Yang, X., Hong, H., Grailer, J.J., Rowland, I.J., Javadi, A., Hurley, S.A.: cRGD-functionalized, DOX-conjugated, and Cu-labeled superparamagnetic iron oxide nanoparticles for targeted anticancer drug delivery and PET/MR imaging. Biomaterials 32, 4151 (2011)CrossRef Yang, X., Hong, H., Grailer, J.J., Rowland, I.J., Javadi, A., Hurley, S.A.: cRGD-functionalized, DOX-conjugated, and Cu-labeled superparamagnetic iron oxide nanoparticles for targeted anticancer drug delivery and PET/MR imaging. Biomaterials 32, 4151 (2011)CrossRef
76.
Zurück zum Zitat Pressly, E.D., Pierce, R.A., Connal, L.A., Hawker, C.J., Liu, Y.: Nanoparticle PET/CT imaging of natriuretic peptide clearance receptor in prostate cancer. Bioconjug. Chem. 24, 196 (2013)CrossRef Pressly, E.D., Pierce, R.A., Connal, L.A., Hawker, C.J., Liu, Y.: Nanoparticle PET/CT imaging of natriuretic peptide clearance receptor in prostate cancer. Bioconjug. Chem. 24, 196 (2013)CrossRef
77.
Zurück zum Zitat Locatelli, E., Gil, L., Israel, L.L., Passoni, L., Naddaka, M., Pucci, A.: Biocompatible nanocomposite for PET/MRI hybrid imaging. Int. J. Nanomed. 7, 6021–6033 (2012) Locatelli, E., Gil, L., Israel, L.L., Passoni, L., Naddaka, M., Pucci, A.: Biocompatible nanocomposite for PET/MRI hybrid imaging. Int. J. Nanomed. 7, 6021–6033 (2012)
78.
Zurück zum Zitat Kim, S.M., Chae, M.K., Yim, M.S., Jeong, I.H., Cho, J., Lee, C.: Hybrid PET/MR imaging of tumors using an oleanolic acid-conjugated nanoparticle. Biomaterials 34, 8114 (2013)CrossRef Kim, S.M., Chae, M.K., Yim, M.S., Jeong, I.H., Cho, J., Lee, C.: Hybrid PET/MR imaging of tumors using an oleanolic acid-conjugated nanoparticle. Biomaterials 34, 8114 (2013)CrossRef
79.
Zurück zum Zitat Lee, D.E., Na, J.H., Lee, S., Kang, C.M., Kim, H.N., Han, S.J.: Facile method to radiolabel glycol chitosan nanoparticles with (64)Cu via copper-free click chemistry for micropet imaging. Mol. Pharm. 10, 2190 (2013)CrossRef Lee, D.E., Na, J.H., Lee, S., Kang, C.M., Kim, H.N., Han, S.J.: Facile method to radiolabel glycol chitosan nanoparticles with (64)Cu via copper-free click chemistry for micropet imaging. Mol. Pharm. 10, 2190 (2013)CrossRef
80.
Zurück zum Zitat Liu, Y., Welch, M.J.: Nanoparticles labeled with positron emitting nuclides: advantages, methods, and applications. Bioconjug. Chem. 23, 671–682 (2012)CrossRef Liu, Y., Welch, M.J.: Nanoparticles labeled with positron emitting nuclides: advantages, methods, and applications. Bioconjug. Chem. 23, 671–682 (2012)CrossRef
81.
Zurück zum Zitat Zeng, D., Lee, N.S., Liu, Y., Zhou, D., Dence, C.S., Wooley, K.L.: 64Cu core-labeled nanoparticles with high specific activity via metal-free click chemistry. ACS Nano 6, 5209–5219 (2012)CrossRef Zeng, D., Lee, N.S., Liu, Y., Zhou, D., Dence, C.S., Wooley, K.L.: 64Cu core-labeled nanoparticles with high specific activity via metal-free click chemistry. ACS Nano 6, 5209–5219 (2012)CrossRef
82.
Zurück zum Zitat Zhao, Y., Sultan, D., Detering, L., Cho, S., Sun, G., Pierce, R.: Copper-64-alloyed gold nanoparticles for cancer imaging: improved radiolabel stability and diagnostic accuracy. Angew. Chem. 53, 156–159 (2013)CrossRef Zhao, Y., Sultan, D., Detering, L., Cho, S., Sun, G., Pierce, R.: Copper-64-alloyed gold nanoparticles for cancer imaging: improved radiolabel stability and diagnostic accuracy. Angew. Chem. 53, 156–159 (2013)CrossRef
83.
Zurück zum Zitat Wang, J., Mi, P., Lin, G., Wang, Y.X., Liu, G., Chen, X.: Imaging guided delivery of RNAi for anticancer treatment. Adv. Drug Deliv. Rev. 104, 44–60 (2016)CrossRef Wang, J., Mi, P., Lin, G., Wang, Y.X., Liu, G., Chen, X.: Imaging guided delivery of RNAi for anticancer treatment. Adv. Drug Deliv. Rev. 104, 44–60 (2016)CrossRef
84.
Zurück zum Zitat Black, K.C.L., Akers, W.J., Sudlow, G., Xu, B., Laforest, R., Achilefu, S.: Dual-radiolabeled nanoparticle SPECT probes for bioimaging. Nanoscale 7, 440–444 (2015)CrossRef Black, K.C.L., Akers, W.J., Sudlow, G., Xu, B., Laforest, R., Achilefu, S.: Dual-radiolabeled nanoparticle SPECT probes for bioimaging. Nanoscale 7, 440–444 (2015)CrossRef
85.
Zurück zum Zitat Chrastina, A., Schnitzer, J.E.: Iodine-125 radiolabeling of silver nanoparticles for in vivo SPECT imaging. Int. J. Nanomed. 5, 653–659 (2010) Chrastina, A., Schnitzer, J.E.: Iodine-125 radiolabeling of silver nanoparticles for in vivo SPECT imaging. Int. J. Nanomed. 5, 653–659 (2010)
86.
Zurück zum Zitat Perrier, M., Busson, M., Massasso, G., Long, J., Boudousq, V., Pouget, J.P.: 201Tl+-labelled prussian blue nanoparticles as contrast agents for SPECT scintigraphy. Nanoscale 6, 13425 (2014)CrossRef Perrier, M., Busson, M., Massasso, G., Long, J., Boudousq, V., Pouget, J.P.: 201Tl+-labelled prussian blue nanoparticles as contrast agents for SPECT scintigraphy. Nanoscale 6, 13425 (2014)CrossRef
87.
Zurück zum Zitat Karina, B.H.B., Maeda, O.J.M., Roberta, L.G., Batista, A.C., Coral, D.O.C.E., Ehara, W.M.A.: Molecular markers for breast cancer: prediction on tumor behavior. Dis. Markers 513158 (2014) Karina, B.H.B., Maeda, O.J.M., Roberta, L.G., Batista, A.C., Coral, D.O.C.E., Ehara, W.M.A.: Molecular markers for breast cancer: prediction on tumor behavior. Dis. Markers 513158 (2014)
88.
Zurück zum Zitat Zhao, Y., Pang, B., Luehmann, H., Detering, L., Yang, X., Sultan, D.: Gold nanoparticles doped with (199) au atoms and their use for targeted cancer imaging by SPECT. Adv. Healthc. Mater. 5, 928 (2016)CrossRef Zhao, Y., Pang, B., Luehmann, H., Detering, L., Yang, X., Sultan, D.: Gold nanoparticles doped with (199) au atoms and their use for targeted cancer imaging by SPECT. Adv. Healthc. Mater. 5, 928 (2016)CrossRef
89.
Zurück zum Zitat Piwnica-Worms, D.: On in vivo imaging in cancer. Cold Spring Harbor Persp. Biol. 2, a003848 (2010) Piwnica-Worms, D.: On in vivo imaging in cancer. Cold Spring Harbor Persp. Biol. 2, a003848 (2010)
90.
Zurück zum Zitat Oleinikov, V.A.: Semiconductor fluorescent nanocrystals (quantum dots) in biological biochips. Bioorg. Khim. 37, 171–189 (2011) Oleinikov, V.A.: Semiconductor fluorescent nanocrystals (quantum dots) in biological biochips. Bioorg. Khim. 37, 171–189 (2011)
91.
Zurück zum Zitat Chan, W.C., Nie, S.: Quantum dot bioconjugates for ultrasensitive nonisotopic detection. Science 1998, 281 (2016) Chan, W.C., Nie, S.: Quantum dot bioconjugates for ultrasensitive nonisotopic detection. Science 1998, 281 (2016)
92.
Zurück zum Zitat Bruchez, M., Moronne, M., Gin, P.: Semiconductor nanocrystals as fluorescent biological labels. Science 281, 2013–2016 (1998)CrossRef Bruchez, M., Moronne, M., Gin, P.: Semiconductor nanocrystals as fluorescent biological labels. Science 281, 2013–2016 (1998)CrossRef
93.
Zurück zum Zitat Valizadeh, A., Mikaeili, H., Samiei, M., Farkhani, S.M., Zarghami, N., Kouhi, M.: Quantum dots: synthesis, bioapplications, and toxicity. Nanoscale Res. Lett. 7, 480 (2012)CrossRef Valizadeh, A., Mikaeili, H., Samiei, M., Farkhani, S.M., Zarghami, N., Kouhi, M.: Quantum dots: synthesis, bioapplications, and toxicity. Nanoscale Res. Lett. 7, 480 (2012)CrossRef
94.
Zurück zum Zitat Michalet, X., Pinaud, F.F., Bentolila, L.A., Tsay, J.M., Doose, S., Li, J.J.: Quantum dots for live cells, in vivo imaging, and diagnostics. Science 307, 538 (2005)CrossRef Michalet, X., Pinaud, F.F., Bentolila, L.A., Tsay, J.M., Doose, S., Li, J.J.: Quantum dots for live cells, in vivo imaging, and diagnostics. Science 307, 538 (2005)CrossRef
95.
Zurück zum Zitat Dubertret, B., Skourides, P., Norris, D.J., Noireaux, V., Brivanlou, A.H., Libchaber, A.: In vivo imaging of quantum dots encapsulated in phospholipid micelles. Science 298, 1759 (2002)CrossRef Dubertret, B., Skourides, P., Norris, D.J., Noireaux, V., Brivanlou, A.H., Libchaber, A.: In vivo imaging of quantum dots encapsulated in phospholipid micelles. Science 298, 1759 (2002)CrossRef
96.
Zurück zum Zitat Larson, D.R., Zipfel, W.R., Williams, R.M., Clark, S.W., Bruchez, M.P., Wise, F.W.: Water-soluble quantum dots for multiphoton fluorescence imaging in vivo. Science 300, 1434 (2003)CrossRef Larson, D.R., Zipfel, W.R., Williams, R.M., Clark, S.W., Bruchez, M.P., Wise, F.W.: Water-soluble quantum dots for multiphoton fluorescence imaging in vivo. Science 300, 1434 (2003)CrossRef
97.
Zurück zum Zitat Gao, X., Yang, L., Petros, J.A., Marshall, F.F., Simons, J.W., Nie, S.: In vivo, molecular and cellular imaging with quantum dots. Curr. Opin. Biotech. 16, 63–72 (2005)CrossRef Gao, X., Yang, L., Petros, J.A., Marshall, F.F., Simons, J.W., Nie, S.: In vivo, molecular and cellular imaging with quantum dots. Curr. Opin. Biotech. 16, 63–72 (2005)CrossRef
98.
Zurück zum Zitat Ballou, B., Lagerholm, B.C., Ernst, L.A., Bruchez, M.P., Waggoner, A.S.: Noninvasive imaging of quantum dots in mice. Bioconjug. Chem. 15, 79–86 (2004)CrossRef Ballou, B., Lagerholm, B.C., Ernst, L.A., Bruchez, M.P., Waggoner, A.S.: Noninvasive imaging of quantum dots in mice. Bioconjug. Chem. 15, 79–86 (2004)CrossRef
99.
Zurück zum Zitat Cai, W., Shin, D., Chen, K., Olivier, G., Cao, Q., Wang, X.: Peptide-labeled near-infrared quantum dots for imaging tumor vasculature in living subjects. Nano Lett. 6, 669 (2006)CrossRef Cai, W., Shin, D., Chen, K., Olivier, G., Cao, Q., Wang, X.: Peptide-labeled near-infrared quantum dots for imaging tumor vasculature in living subjects. Nano Lett. 6, 669 (2006)CrossRef
100.
Zurück zum Zitat Gao, X., Cui, Y., Levenson, R.M., Chung, L.W., Nie, S.: In vivo cancer targeting and imaging with semiconductor quantum dots. Nat. Biotech. 22, 969 (2004)CrossRef Gao, X., Cui, Y., Levenson, R.M., Chung, L.W., Nie, S.: In vivo cancer targeting and imaging with semiconductor quantum dots. Nat. Biotech. 22, 969 (2004)CrossRef
101.
Zurück zum Zitat Lim, S.Y., Shen, W., Gao, Z.: Carbon quantum dots and their applications. Chem. Soc. Rev. 44, 362–381 (2015)CrossRef Lim, S.Y., Shen, W., Gao, Z.: Carbon quantum dots and their applications. Chem. Soc. Rev. 44, 362–381 (2015)CrossRef
102.
Zurück zum Zitat Liu, R., Wu, D., Liu, S., Koynov, K., Knoll, W., Li, Q.: An aqueous route to multicolor photoluminescent carbon dots using silica spheres as carriers. Angew. Chem. 48, 4598–4601 (2010)CrossRef Liu, R., Wu, D., Liu, S., Koynov, K., Knoll, W., Li, Q.: An aqueous route to multicolor photoluminescent carbon dots using silica spheres as carriers. Angew. Chem. 48, 4598–4601 (2010)CrossRef
103.
Zurück zum Zitat Baker, S., Baker, G.: Luminescent carbon nanodots: emergent nanolights. Angew. Chem. 49, 6726–6744 (2010)CrossRef Baker, S., Baker, G.: Luminescent carbon nanodots: emergent nanolights. Angew. Chem. 49, 6726–6744 (2010)CrossRef
104.
Zurück zum Zitat Liu, Z., Chen, W., Li, Y., Xu, Q.: Integrin αvβ3-targeted C-dot nanocomposites as multifunctional agents for cell targeting and photoacoustic imaging of superficial malignant tumors. Anal. Chem. 88, 11955 (2016)CrossRef Liu, Z., Chen, W., Li, Y., Xu, Q.: Integrin αvβ3-targeted C-dot nanocomposites as multifunctional agents for cell targeting and photoacoustic imaging of superficial malignant tumors. Anal. Chem. 88, 11955 (2016)CrossRef
105.
Zurück zum Zitat Yang, S.T., Cao, L., Luo, P.G., Lu, F., Wang, X., Wang, H.: Carbon dots for optical imaging in vivo. J. Am. Chem. Soc. 131, 11308 (2009)CrossRef Yang, S.T., Cao, L., Luo, P.G., Lu, F., Wang, X., Wang, H.: Carbon dots for optical imaging in vivo. J. Am. Chem. Soc. 131, 11308 (2009)CrossRef
106.
Zurück zum Zitat Wu, L., Luderer, M., Yang, X., Swain, C., Zhang, H., Nelson, K.: Surface passivation of carbon nanoparticles with branched macromolecules influences near infrared bioimaging. Theranostics 3, 677–686 (2013)CrossRef Wu, L., Luderer, M., Yang, X., Swain, C., Zhang, H., Nelson, K.: Surface passivation of carbon nanoparticles with branched macromolecules influences near infrared bioimaging. Theranostics 3, 677–686 (2013)CrossRef
107.
Zurück zum Zitat Huang, Y.F., Zhou, X., Zhou, R., Zhang, H., Kang, K.B., Zhao, M.: One-pot synthesis of highly luminescent carbon quantum dots and their nontoxic ingestion by zebrafish for in vivo imaging. Chemistry 20, 5640 (2014)CrossRef Huang, Y.F., Zhou, X., Zhou, R., Zhang, H., Kang, K.B., Zhao, M.: One-pot synthesis of highly luminescent carbon quantum dots and their nontoxic ingestion by zebrafish for in vivo imaging. Chemistry 20, 5640 (2014)CrossRef
108.
Zurück zum Zitat Zheng, M., Ruan, S., Liu, S., Sun, T., Qu, D., Zhao, H.: Self-targeting fluorescent carbon dots for diagnosis of brain cancer cells. ACS Nano 9, 11455 (2015)CrossRef Zheng, M., Ruan, S., Liu, S., Sun, T., Qu, D., Zhao, H.: Self-targeting fluorescent carbon dots for diagnosis of brain cancer cells. ACS Nano 9, 11455 (2015)CrossRef
110.
Zurück zum Zitat Smith, B.R., Gambhir, S.S.: Nanomaterials for in vivo imaging. Chem. Rev. 117, 901 (2017)CrossRef Smith, B.R., Gambhir, S.S.: Nanomaterials for in vivo imaging. Chem. Rev. 117, 901 (2017)CrossRef
111.
Zurück zum Zitat Liu, T., Shi, S., Liang, C., Shen, S., Cheng, L., Wang, C.: Iron oxide decorated MoS2 nanosheets with double PEGylation for chelator-free radiolabeling and multimodal imaging guided photothermal therapy. ACS Nano 9, 950–960 (2015)CrossRef Liu, T., Shi, S., Liang, C., Shen, S., Cheng, L., Wang, C.: Iron oxide decorated MoS2 nanosheets with double PEGylation for chelator-free radiolabeling and multimodal imaging guided photothermal therapy. ACS Nano 9, 950–960 (2015)CrossRef
112.
Zurück zum Zitat Fang, C., Zhang, M.: Nanoparticle-based theragnostics: integrating diagnostic and therapeutic potentials in nanomedicine. J. Control. Release 146, 2 (2010)CrossRef Fang, C., Zhang, M.: Nanoparticle-based theragnostics: integrating diagnostic and therapeutic potentials in nanomedicine. J. Control. Release 146, 2 (2010)CrossRef
113.
Zurück zum Zitat Mccarthy, J.R., Weissleder, R.: Multifunctional magnetic nanoparticles for targeted imaging and therapy. Adv. Drug Deliv. Rev. 60, 1241–1251 (2008)CrossRef Mccarthy, J.R., Weissleder, R.: Multifunctional magnetic nanoparticles for targeted imaging and therapy. Adv. Drug Deliv. Rev. 60, 1241–1251 (2008)CrossRef
114.
Zurück zum Zitat Hong, G., Diao, S., Antaris, A.L., Dai, H.: Carbon nanomaterials for biological imaging and nanomedicinal therapy. Chem. Rev. 115, 10816 (2015)CrossRef Hong, G., Diao, S., Antaris, A.L., Dai, H.: Carbon nanomaterials for biological imaging and nanomedicinal therapy. Chem. Rev. 115, 10816 (2015)CrossRef
115.
Zurück zum Zitat Huang, X., Elsayed, I.H., Qian, W., Elsayed, M.A.: Cancer cell imaging and photothermal therapy in the near-infrared region by using gold nanorods. J. Am. Chem. Soc. 128, 2115 (2006)CrossRef Huang, X., Elsayed, I.H., Qian, W., Elsayed, M.A.: Cancer cell imaging and photothermal therapy in the near-infrared region by using gold nanorods. J. Am. Chem. Soc. 128, 2115 (2006)CrossRef
116.
Zurück zum Zitat Everts, M., Saini, V., Leddon, J.L., Kok, R.J., Stoff-Khalili, M., Preuss, M.A., Milican, C.L., Perkins, G., Brown, J.M., Bagaria, H., Nikles, D.E., Johnson, D.T., Zharov, V.P., Curiel, D.T.: Covalently linked au nanoparticles to a viral vector: potential for combined photothermal and gene cancer therapy. Nano Lett. 6, 587 (2006)CrossRef Everts, M., Saini, V., Leddon, J.L., Kok, R.J., Stoff-Khalili, M., Preuss, M.A., Milican, C.L., Perkins, G., Brown, J.M., Bagaria, H., Nikles, D.E., Johnson, D.T., Zharov, V.P., Curiel, D.T.: Covalently linked au nanoparticles to a viral vector: potential for combined photothermal and gene cancer therapy. Nano Lett. 6, 587 (2006)CrossRef
117.
Zurück zum Zitat Khlebtsov, B., Zharov, V., Melnikov, A., Tuchin, V., Khlebtsov, N.: Optical amplification of photothermal therapy with gold nanoparticles and nanoclusters. Nanotechnology 17, 5167 (2006)CrossRef Khlebtsov, B., Zharov, V., Melnikov, A., Tuchin, V., Khlebtsov, N.: Optical amplification of photothermal therapy with gold nanoparticles and nanoclusters. Nanotechnology 17, 5167 (2006)CrossRef
118.
Zurück zum Zitat Zerda, A.D.L., Zavaleta, C., Keren, S., Vaithilingam, S., Bodapati, S., Liu, Z.: Carbon nanotubes as photoacoustic molecular imaging agents in living mice. Nat. Nanotech. 3, 557–562 (2008)CrossRef Zerda, A.D.L., Zavaleta, C., Keren, S., Vaithilingam, S., Bodapati, S., Liu, Z.: Carbon nanotubes as photoacoustic molecular imaging agents in living mice. Nat. Nanotech. 3, 557–562 (2008)CrossRef
119.
Zurück zum Zitat Chamberland, D.L., Agarwal, A., Kotov, N., Brian, F.J., Carson, P.L., Wang, X.: Photoacoustic tomography of joints aided by an etanercept-conjugated gold nanoparticle contrast agent-an ex vivo preliminary rat study. Nanotechnology 19, 095101 (2008)CrossRef Chamberland, D.L., Agarwal, A., Kotov, N., Brian, F.J., Carson, P.L., Wang, X.: Photoacoustic tomography of joints aided by an etanercept-conjugated gold nanoparticle contrast agent-an ex vivo preliminary rat study. Nanotechnology 19, 095101 (2008)CrossRef
120.
Zurück zum Zitat Wang, Y., Xie, X., Wang, X., Ku, G., Gill, K.L., O’Neal, D.P., Stoica, G., Wang, L.V.: Photoacoustic tomography of a nanoshell contrast agent in the in vivo rat brain. Nano Lett. 4, 1689–1692 (2004)CrossRef Wang, Y., Xie, X., Wang, X., Ku, G., Gill, K.L., O’Neal, D.P., Stoica, G., Wang, L.V.: Photoacoustic tomography of a nanoshell contrast agent in the in vivo rat brain. Nano Lett. 4, 1689–1692 (2004)CrossRef
121.
Zurück zum Zitat Agarwal, A., Huang, S.W., Odonnell, M., Day, K.C.: Targeted gold nanorod contrast agent for prostate cancer detection by photoacoustic imaging. J. Appl. Phys. 102, 064701-064701-4 (2007) Agarwal, A., Huang, S.W., Odonnell, M., Day, K.C.: Targeted gold nanorod contrast agent for prostate cancer detection by photoacoustic imaging. J. Appl. Phys. 102, 064701-064701-4 (2007)
122.
Zurück zum Zitat Kim, J.W., Galanzha, E.I., Shashkov, E.V., Moon, H.M., Zharov, V.P.: Golden carbon nanotubes as multimodal photoacoustic and photothermal high-contrast molecular agents. Nat. Nanotech. 4, 688–694 (2009)CrossRef Kim, J.W., Galanzha, E.I., Shashkov, E.V., Moon, H.M., Zharov, V.P.: Golden carbon nanotubes as multimodal photoacoustic and photothermal high-contrast molecular agents. Nat. Nanotech. 4, 688–694 (2009)CrossRef
123.
Zurück zum Zitat Sheng, Z., Hu, D., Xue, M., He, M., Gong, P., Cai, L.: Indocyanine green nanoparticles for theranostic applications. Nano-Micro Lett. 5, 145–150 (2013)CrossRef Sheng, Z., Hu, D., Xue, M., He, M., Gong, P., Cai, L.: Indocyanine green nanoparticles for theranostic applications. Nano-Micro Lett. 5, 145–150 (2013)CrossRef
124.
Zurück zum Zitat Sheng, Z., Hu, D., Zheng, M., Zhao, P., Liu, H., Gao, D.: Smart human serum albumin-indocyanine green nanoparticles generated by programmed assembly for dual-modal imaging-guided cancer synergistic phototherapy. ACS Nano 8, 12310 (2014)CrossRef Sheng, Z., Hu, D., Zheng, M., Zhao, P., Liu, H., Gao, D.: Smart human serum albumin-indocyanine green nanoparticles generated by programmed assembly for dual-modal imaging-guided cancer synergistic phototherapy. ACS Nano 8, 12310 (2014)CrossRef
125.
Zurück zum Zitat Savic, R., Luo, L., Eisenberg, L., Maysinger, D.: Micellar nanocontainers distribute to definedcytoplasmic organelles. Science 300, 615–618 (2003)CrossRef Savic, R., Luo, L., Eisenberg, L., Maysinger, D.: Micellar nanocontainers distribute to definedcytoplasmic organelles. Science 300, 615–618 (2003)CrossRef
126.
Zurück zum Zitat Torchilin, V.P.: Micellar nanocarriers: pharmaceutical perspectives. Pharm. Res. 24, 1 (2007)CrossRef Torchilin, V.P.: Micellar nanocarriers: pharmaceutical perspectives. Pharm. Res. 24, 1 (2007)CrossRef
127.
Zurück zum Zitat Miura, Y., Tsuji, A.B., Sugyo, A., Sudo, H., Aoki, I., Inubushi, M.: Polymeric micelle platform for multimodal tomographic imaging to detect scirrhous gastric cancer. ACS Biomater. Sci. Eng. 1, 1067–1076 (2015)CrossRef Miura, Y., Tsuji, A.B., Sugyo, A., Sudo, H., Aoki, I., Inubushi, M.: Polymeric micelle platform for multimodal tomographic imaging to detect scirrhous gastric cancer. ACS Biomater. Sci. Eng. 1, 1067–1076 (2015)CrossRef
128.
Zurück zum Zitat Lu, A.H., Salabas, E.L., Schuth, F.: Magnetic nanoparticles: synthesis, protection, functionalization, and application. Angew. Chem. Int. Ed. 46, 1222 (2007)CrossRef Lu, A.H., Salabas, E.L., Schuth, F.: Magnetic nanoparticles: synthesis, protection, functionalization, and application. Angew. Chem. Int. Ed. 46, 1222 (2007)CrossRef
129.
Zurück zum Zitat Frimpong, R.A., Hilt, J.Z.: Magnetic nanoparticles in biomedicine: synthesis, functionalization and applications. Nanomedicine 5, 1401 (2010)CrossRef Frimpong, R.A., Hilt, J.Z.: Magnetic nanoparticles in biomedicine: synthesis, functionalization and applications. Nanomedicine 5, 1401 (2010)CrossRef
130.
Zurück zum Zitat Sinha, R., Kim, G.J., Nie, S., Shin, D.M.: Nanotechnology in cancer therapeutics: bioconjugated nanoparticles for drug delivery. Mol. Cancer Ther. 2006, 5 (1909) Sinha, R., Kim, G.J., Nie, S., Shin, D.M.: Nanotechnology in cancer therapeutics: bioconjugated nanoparticles for drug delivery. Mol. Cancer Ther. 2006, 5 (1909)
131.
Zurück zum Zitat Li, J., Wang, Y., Liang, R., An, X., Wang, K., Shen, G.: Recent advances in targeted nanoparticles drug delivery to melanoma. Nanomed. Nanotech. Biol. Med. 11, 769–794 (2015)CrossRef Li, J., Wang, Y., Liang, R., An, X., Wang, K., Shen, G.: Recent advances in targeted nanoparticles drug delivery to melanoma. Nanomed. Nanotech. Biol. Med. 11, 769–794 (2015)CrossRef
132.
Zurück zum Zitat Sailor, M.J., Park, J.H.: Hybrid nanoparticles for detection and treatment of cancer. Adv. Mater. 24, 3779 (2012)CrossRef Sailor, M.J., Park, J.H.: Hybrid nanoparticles for detection and treatment of cancer. Adv. Mater. 24, 3779 (2012)CrossRef
133.
Zurück zum Zitat Smith, B.R., Kempen, P., Bouley, D., Xu, A., Liu, Z., Melosh, N., Dai, H., Sinclair, R., Gambhir, S.S.: Shape matters: intravital microscopy reveals surprising geometrical dependence for nanoparticles in tumor models of extravasation. Nano Lett. 12, 3369–3377 (2012)CrossRef Smith, B.R., Kempen, P., Bouley, D., Xu, A., Liu, Z., Melosh, N., Dai, H., Sinclair, R., Gambhir, S.S.: Shape matters: intravital microscopy reveals surprising geometrical dependence for nanoparticles in tumor models of extravasation. Nano Lett. 12, 3369–3377 (2012)CrossRef
134.
Zurück zum Zitat Lobatto, M.E., Calcagno, C., Millon, A., Senders, M.L., Fay, F., Robson, P.M.: Atherosclerotic plaque targeting mechanism of long-circulating nanoparticles established by multimodal imaging. ACS Nano 9, 1837–1847 (2015)CrossRef Lobatto, M.E., Calcagno, C., Millon, A., Senders, M.L., Fay, F., Robson, P.M.: Atherosclerotic plaque targeting mechanism of long-circulating nanoparticles established by multimodal imaging. ACS Nano 9, 1837–1847 (2015)CrossRef
135.
Zurück zum Zitat Prabhakar, U., Maeda, H., Jain, R.K., Sevickmuraca, E.M., Zamboni, W., Farokhzad, O.C.: Challenges and key considerations of the enhanced permeability and retention effect for nanomedicine drug delivery in oncology. Cancer Res. 73, 2412 (2013)CrossRef Prabhakar, U., Maeda, H., Jain, R.K., Sevickmuraca, E.M., Zamboni, W., Farokhzad, O.C.: Challenges and key considerations of the enhanced permeability and retention effect for nanomedicine drug delivery in oncology. Cancer Res. 73, 2412 (2013)CrossRef
136.
Zurück zum Zitat Toy, R., Bauer, L., Hoimes, C., Ghaghada, K.B., Karathanasis, E.: Targeted nanotechnology for cancer imaging. Adv. Drug Deliv. Rev. 76, 79 (2014)CrossRef Toy, R., Bauer, L., Hoimes, C., Ghaghada, K.B., Karathanasis, E.: Targeted nanotechnology for cancer imaging. Adv. Drug Deliv. Rev. 76, 79 (2014)CrossRef
137.
Zurück zum Zitat Louie, A.: Multimodality imaging probes: design and challenges. Chem. Rev. 110, 3146–3195 (2010)CrossRef Louie, A.: Multimodality imaging probes: design and challenges. Chem. Rev. 110, 3146–3195 (2010)CrossRef
138.
Zurück zum Zitat Kim, J., Park, S., Lee, J.E., Jin, S.M., Lee, J.H., Lee, I.S.: Designed fabrication of multifunctional magnetic gold nanoshells and their application to magnetic resonance imaging and photothermal therapy. Angew. Chem. 45, 7754–7758 (2006)CrossRef Kim, J., Park, S., Lee, J.E., Jin, S.M., Lee, J.H., Lee, I.S.: Designed fabrication of multifunctional magnetic gold nanoshells and their application to magnetic resonance imaging and photothermal therapy. Angew. Chem. 45, 7754–7758 (2006)CrossRef
139.
Zurück zum Zitat Kelkar, S.S., Reineke, T.M.: Theranostics: combining imaging and therapy. Bioconjug. Chem. 22, 1879–1903 (2011)CrossRef Kelkar, S.S., Reineke, T.M.: Theranostics: combining imaging and therapy. Bioconjug. Chem. 22, 1879–1903 (2011)CrossRef
140.
Zurück zum Zitat Kim, J., Kim, H.S., Lee, N., Kim, T., Kim, H., Yu, T.: Multifunctional uniform nanoparticles composed of a magnetite nanocrystal core and a mesoporous silica shell for magnetic resonance and fluorescence imaging and for drug delivery. Angew. Chem. 47, 8438 (2008)CrossRef Kim, J., Kim, H.S., Lee, N., Kim, T., Kim, H., Yu, T.: Multifunctional uniform nanoparticles composed of a magnetite nanocrystal core and a mesoporous silica shell for magnetic resonance and fluorescence imaging and for drug delivery. Angew. Chem. 47, 8438 (2008)CrossRef
141.
Zurück zum Zitat Kelkar, S.S., Reineke, T.M.: Theranostics: combining imaging and therapy. Bioconjug. Chem. 2011, 22 (1879) Kelkar, S.S., Reineke, T.M.: Theranostics: combining imaging and therapy. Bioconjug. Chem. 2011, 22 (1879)
Metadaten
Titel
Functional Micro-/Nanomaterials for Imaging Technology
verfasst von
Waner Chen
Wei Ma
Chunpeng Zou
Yan Yang
Gaoyi Yang
Li Liu
Zhe Liu
Copyright-Jahr
2018
Verlag
Springer Singapore
DOI
https://doi.org/10.1007/978-981-10-4804-3_1

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