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Erschienen in: Cellulose 3/2014

01.06.2014 | Original Paper

Antibacterial modification of cellulose fibers by grafting β-cyclodextrin and inclusion with ciprofloxacin

verfasst von: Chao Dong, Ying Ye, Liying Qian, Guanglei Zhao, Beihai He, Huining Xiao

Erschienen in: Cellulose | Ausgabe 3/2014

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Abstract

Antibacterial-modified cellulose fiber was prepared by covalently bonding β-cyclodextrin (β-CD) with cellulose fiber via citric acid (CA) as crosslinking agent, followed by the inclusion of ciprofloxacin hydrochloride (CipHCl) as antibiotic. Effects of reaction time, temperature, concentration of β-cyclodextrin citrate (CA-β-CD) and pH on the grafting reaction were investigated, and the grafting ratio of β-CD onto cellulose fibers was 9.7 % at optimal conditions; the loading and releasing behaviors of CipHCl into/from β-CD grafted cellulose fibers were also revealed, the load amount of CipHCl into grafted cellulose fibers increased remarkably, and the release of CipHCl from the grafted cellulose fibers was prolonged. The microstructure, phase and thermal stability of modified cellulose fibers were characterized by FT-IR, 13C CPMAS NMR, X-ray diffraction and TGA. Considerably longer bacterial activity against E. coli and S. aureus was observed for grafted fibers loading CipHCl compared to virgin ones. Optical and mechanical properties of the paper sheets decreased generally with more antibacterial-modified fibers added.

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Metadaten
Titel
Antibacterial modification of cellulose fibers by grafting β-cyclodextrin and inclusion with ciprofloxacin
verfasst von
Chao Dong
Ying Ye
Liying Qian
Guanglei Zhao
Beihai He
Huining Xiao
Publikationsdatum
01.06.2014
Verlag
Springer Netherlands
Erschienen in
Cellulose / Ausgabe 3/2014
Print ISSN: 0969-0239
Elektronische ISSN: 1572-882X
DOI
https://doi.org/10.1007/s10570-014-0249-8

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