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Journal of Computational Electronics

Erschienen in:

11.10.2022

Proposing of SPR biosensor based on 2D Ti₃C₂T_x MXene for uric acid detection ımmobilized by uricase enzyme

verfasst von: Maryam Ghodrati, Ali Mir, Ali Farmani

Erschienen in: Journal of Computational Electronics | Ausgabe 1/2023

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Abstract

This paper proposes a surface plasmon resonance (SPR) biosensor based on Ti₃C₂T_x MXene two-dimensional material to detect uric acid by utilizing urate oxidase enzyme. The proposed biosensor is a free space structure using Kretschmann configuration to stimulate the surface plasmons. The structure consists of SF11 prism, BK7 glass, silver (Ag), tungsten disulfide (WS₂), graphene, Ti₃C₂T_x MXene, and the sensing medium. The minimum reflection, sensitivity, figure of merit, and detection accuracy of the SPR are investigated using the numerical method of FDTD in the visible region. Molarity varies from 0 to 500 ppm and refractive index from 1.3300 to 1.3336 for the sensing layer. The results indicate that the highest sensitivity of 273.53 deg/RIU can be achieved with a thickness of 50 nm Ag and a monolayer of WS₂, a monolayer of graphene, and four layers of Ti₃C₂T_x MXene, at 633 nm wavelength.

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Titel: Proposing of SPR biosensor based on 2D Ti3C2Tx MXene for uric acid detection ımmobilized by uricase enzyme
verfasst von: Maryam Ghodrati
Ali Mir
Ali Farmani
Publikationsdatum: 11.10.2022
Verlag: Springer US
Erschienen in: Journal of Computational Electronics / Ausgabe 1/2023
Print ISSN: 1569-8025
Elektronische ISSN: 1572-8137
DOI: https://doi.org/10.1007/s10825-022-01959-w

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