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Medical & Biological Engineering & Computing

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01.07.2007 | Original Article

Design of electrodes and current limits for low frequency electrical impedance tomography of the brain

verfasst von: O. Gilad, L. Horesh, D. S. Holder

Erschienen in: Medical & Biological Engineering & Computing | Ausgabe 7/2007

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Abstract

For the novel application of recording of resistivity changes related to neuronal depolarization in the brain with electrical impedance tomography, optimal recording is with applied currents below 100 Hz, which might cause neural stimulation of skin or underlying brain. The purpose of this work was to develop a method for application of low frequency currents to the scalp, which delivered the maximum current without significant stimulation of skin or underlying brain. We propose a recessed electrode design which enabled current injection with an acceptable skin sensation to be increased from 100 μA using EEG electrodes, to 1 mA in 16 normal volunteers. The effect of current delivered to the brain was assessed with an anatomically realistic finite element model of the adult head. The modelled peak cerebral current density was 0.3 A/m², which was 5 to 25-fold less than the threshold for stimulation of the brain estimated from literature review.

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Titel: Design of electrodes and current limits for low frequency electrical impedance tomography of the brain
verfasst von: O. Gilad
L. Horesh
D. S. Holder
Publikationsdatum: 01.07.2007
Verlag: Springer-Verlag
Erschienen in: Medical & Biological Engineering & Computing / Ausgabe 7/2007
Print ISSN: 0140-0118
Elektronische ISSN: 1741-0444
DOI: https://doi.org/10.1007/s11517-007-0209-7

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