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Cognitive Neurodynamics
Erschienen in: Cognitive Neurodynamics 3/2012

01.06.2012 | Research Article

The population firing rate in the presence of GABAergic tonic inhibition in single neurons and application to general anaesthesia

verfasst von: Axel Hutt

Erschienen in: Cognitive Neurodynamics | Ausgabe 3/2012

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Abstract

Tonic inhibition has been found experimentally in single neurons and affects the activity of neural populations. This kind of inhibition is supposed to set the background or resting level of neural activity and plays a role in the brains arousal system, e.g. during general anaesthesia. The work shows how to involve tonic inhibition in population rate-coding models by deriving a novel transfer function. The analytical and numerical study of the novel transfer function reveals the impact of tonic inhibition on the population firing rate. Finally, a first application to a recent neural field model for general anaesthesia discusses the origin of the loss of consciousness during anaesthesia.
Vorheriger Artikel Gap junctions modulate seizures in a mean-field model of general anesthesia for the cortex
Nächster Artikel Exploring the spectrum of dynamical regimes and timescales in spontaneous cortical activity

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Metadaten
Titel
The population firing rate in the presence of GABAergic tonic inhibition in single neurons and application to general anaesthesia
verfasst von
Axel Hutt
Publikationsdatum
01.06.2012
Verlag
Springer Netherlands
Erschienen in
Cognitive Neurodynamics / Ausgabe 3/2012
Print ISSN: 1871-4080
Elektronische ISSN: 1871-4099
DOI
https://doi.org/10.1007/s11571-011-9182-9

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