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Arabian Journal for Science and Engineering

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06.07.2023 | Research Article-Physics

Tuning the Morphology of Au/ZnO Nanocomposite Using Pulsed Laser Ablation for Anticancer Applications

verfasst von: Muidh Alheshibri, Khaled A. Elsayed, Firdos Alam Khan, Shamsuddeen A. Haladu, Filiz Ercan, Emre Çevik, Q. A. Drmosh, T. S. Kayed, M. A. Almessiere

Erschienen in: Arabian Journal for Science and Engineering | Ausgabe 1/2024

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Abstract

Developing a nanosized platform for annihilating cancer cells is highly promising and desirable in the field of nanomedicine especially when an eco-friendly synthesis protocol such as laser ablation is employed. Herein, pulsed laser ablation technique was used to fabricate Au/ZnO nanocomposite in deionized water. The prepared nanostructures were examined using HRTEM, SEM, EDX, XRD, UV–Vis, and Raman spectroscopy. An in vitro cytotoxicity evaluation of the prepared Au/ZnO nanocomposite on human colorectal carcinoma HCT116 and cervical cancer HeLa cells reveals the strong inhibitory action of the nanomaterials on the cancer cells. The influence of the nanocomposites on healthy HEK-293 cell line used as a control was minimal. The outcomes of this work mark the merits of laser ablation in the fabrication of highly pure nanomaterials with good efficacy against cancer cells.

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Nächster Artikel Hybrid Metal Halide Perovskite–Graphene Sensor for Ultra-sensitive X-ray Detection

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Titel: Tuning the Morphology of Au/ZnO Nanocomposite Using Pulsed Laser Ablation for Anticancer Applications
verfasst von: Muidh Alheshibri
Khaled A. Elsayed
Firdos Alam Khan
Shamsuddeen A. Haladu
Filiz Ercan
Emre Çevik
Q. A. Drmosh
T. S. Kayed
M. A. Almessiere
Publikationsdatum: 06.07.2023
Verlag: Springer Berlin Heidelberg
Erschienen in: Arabian Journal for Science and Engineering / Ausgabe 1/2024
Print ISSN: 2193-567X
Elektronische ISSN: 2191-4281
DOI: https://doi.org/10.1007/s13369-023-08061-8

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