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Polymer Bulletin
Erschienen in: Polymer Bulletin 2/2013

01.02.2013 | Original Paper

An improved method for preparing glutaraldehyde cross-linked chitosan–poly(vinyl alcohol) microparticles

verfasst von: Elisa Campos, Patrícia Coimbra, M. H. Gil

Erschienen in: Polymer Bulletin | Ausgabe 2/2013

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Abstract

The features of microparticles, as size, surface structure, and morphology, depend, mainly, on the methodology used for their preparation. Emulsion polymerization techniques are undoubtedly among the most widespread. However, the use of toxic, volatile organic solvents represents a major disadvantage, namely, because of environmental issues. In this study, we prepared glutaraldehyde cross-linked chitosan–poly(vinyl alcohol) microparticles by an improved water-in-oil emulsion technique using corn oil as organic phase. The application of this polymeric blend as microparticle is scarcely investigated. As resulting of the procedure here presented, spherical and smooth surface microparticles were obtained, with mean diameter of 16 μm. The cross-linking reaction between the aldehyde and the amino or the hydroxyl groups formed either an imine (Schiff’s base) or an acetal bond, respectively, as analyzed by infrared spectroscopy. The microparticles here described did not present cytotoxic potential. Accordingly, this study can find promising and successful application in biotechnology.
Vorheriger Artikel Effect of functionalized polyethylenes on clay dispersion in high density polyethylene nanocomposites
Nächster Artikel Polymeric scaffolds based on blends of poly-l-lactic acid (PLLA) with poly-d-l-lactic acid (PLA) prepared via thermally induced phase separation (TIPS): demixing conditions and morphology

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Metadaten
Titel
An improved method for preparing glutaraldehyde cross-linked chitosan–poly(vinyl alcohol) microparticles
verfasst von
Elisa Campos
Patrícia Coimbra
M. H. Gil
Publikationsdatum
01.02.2013
Verlag
Springer-Verlag
Erschienen in
Polymer Bulletin / Ausgabe 2/2013
Print ISSN: 0170-0839
Elektronische ISSN: 1436-2449
DOI
https://doi.org/10.1007/s00289-012-0853-4

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