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Journal of Sol-Gel Science and Technology
Erschienen in: Journal of Sol-Gel Science and Technology 2/2015

01.05.2015 | Original Paper

Functionalization of SBA-16 silica particles for ibuprofen delivery

verfasst von: M. Naghiloo, M. Yousefpour, M. S. Nourbakhsh, Z. Taherian

Erschienen in: Journal of Sol-Gel Science and Technology | Ausgabe 2/2015

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Abstract

In this study, the surface of the hydrothermally synthesized SBA-16 was modified with 3-aminopropyltriethoxysilane (APTES) as a controlled drug delivery system. In this case, ibuprofen was chosen as a drug. Furthermore, it was loaded into the SBA-16 base and functionalized SBA-16. Then, the adsorption and release properties of mention samples were studied. In addition, mesoporous materials were characterized using X-ray diffraction, fourier-transform infra-red spectroscopy, N2 adsorption/desorption analysis and ultra-violet spectroscopy. The results showed that adsorption and release behavior of ibuprofen were extremely depended on various surface properties of SBA-16 particles. Furthermore, it was observed that the sample with a higher percent loaded of ibuprofen exhibited a higher percent of the ibuprofen released molecules in a phosphate buffer solution.

Graphical Abstract

Vorheriger Artikel Structural and optical properties of CuMnCoOx spinel thin films prepared by a citric acid-based sol–gel dip coating route for solar absorber applications
Nächster Artikel Synthesis and luminescent properties of NaLa(MoO4)2:Eu3+,Tb3+ phosphors by microwave-assisted sol–gel method

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Metadaten
Titel
Functionalization of SBA-16 silica particles for ibuprofen delivery
verfasst von
M. Naghiloo
M. Yousefpour
M. S. Nourbakhsh
Z. Taherian
Publikationsdatum
01.05.2015
Verlag
Springer US
Erschienen in
Journal of Sol-Gel Science and Technology / Ausgabe 2/2015
Print ISSN: 0928-0707
Elektronische ISSN: 1573-4846
DOI
https://doi.org/10.1007/s10971-015-3631-6

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