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Erschienen in:
In Vivo, In Vitro, In Silico: Computational Tools for Product and Process Design in Tissue Engineering Kapitel lesen Erstes Kapitel lesen

2013 | OriginalPaper | Buchkapitel

Mathematical Modelling of Regeneration of a Tissue-Engineered Trachea

verfasst von : Greg Lemon, John R. King, Paolo Macchiarini

Erschienen in: Computational Modeling in Tissue Engineering

Verlag: Springer Berlin Heidelberg

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Abstract

One of the most promising recent achievements in the field of regenerative medicine was the first successful transplantation of a tissue-engineered trachea (Macchiarini et al. The Lancet 372(9655), 2023–2030). This land-mark operation has paved the way for developing a host of successful stem cell-based therapies for treating disease, and the exciting possibility of the tissue engineering of whole organs. It has also provided the opportunity for new directions in mathematical and computational modelling for tissue engineering. By way of describing an approach to modelling the regeneration of a tissue-engineered trachea seeded with cells in situ this chapter will highlight some of the opportunities and challenges involved in applying mathematical models to these new therapies.

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Vorheriges Kapitel Mechanobiological Modelling of Angiogenesis: Impact on Tissue Engineering and Bone Regeneration
Fußnoten
1
BBC News, “Windpipe transplant breakthrough” Nov. 2008, http://news.bbc.co.uk/1/hi/7735696.stm
 
2
BBC News, “Windpipe transplant success in UK child” Mar. 2010, http://news.bbc.co.uk/1/hi/8576493.stm
 
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Metadaten
Titel
Mathematical Modelling of Regeneration of a Tissue-Engineered Trachea
verfasst von
Greg Lemon
John R. King
Paolo Macchiarini
Copyright-Jahr
2013
Verlag
Springer Berlin Heidelberg
Buch
Computational Modeling in Tissue Engineering

Print ISBN: 978-3-642-32562-5

Electronic ISBN: 978-3-642-32563-2

Copyright-Jahr: 2013

DOI
https://doi.org/10.1007/8415_2012_145

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