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2019 | OriginalPaper | Buchkapitel

Molecular Mechanisms of Heavy Metal Toxicity in Cancer Progression

verfasst von : Pragati Singh, Deepak Tiwari, Manish Mishra, Dhruv Kumar

Erschienen in: Networking of Mutagens in Environmental Toxicology

Verlag: Springer International Publishing

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Abstract

In last few years, cancer became one of the leading cause of death in humans. There are several factors associated with the cancer initiation and progression including heavy metals. Several heavy metals including arsenic, cadmium, uranium, lead, mercury etc. and heavy metal-containing compounds are toxic to the humans and have been reported to induce mutations in human genome which further leads to the carcinogenesis. This chapter provides the detail understanding of molecular mechanisms and pathway analysis to heavy metal toxicity in human carcinogenesis.

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Metadaten
Titel
Molecular Mechanisms of Heavy Metal Toxicity in Cancer Progression
verfasst von
Pragati Singh
Deepak Tiwari
Manish Mishra
Dhruv Kumar
Copyright-Jahr
2019
DOI
https://doi.org/10.1007/978-3-319-96511-6_3