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Journal of Nanoparticle Research
Erschienen in: Journal of Nanoparticle Research 4/2013

01.04.2013 | Review

New vision to CuO, ZnO, and TiO2 nanoparticles: their outcome and effects

verfasst von: Sandesh Chibber, Shakeel Ahmed Ansari, Rukhsana Satar

Erschienen in: Journal of Nanoparticle Research | Ausgabe 4/2013

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Abstract

Nanomaterials and nanotechnology have attracted more and more attention due to their wide ranges of applications in various fields. With a high level of surface energy, high magnetism, high surface area, and low melting point, engineered nanoparticles (ENPs) has been widely used in industry for various applications. Metal nanoparticles, in particular, have been shown to cause significant biological effects. Review discusses cytotoxic to neurotoxic effects of CuO, ZnO, and TiO2 nanoparticles based on the scenario drawn from various in vitro and in vivo studies. ENPs such as TiO2 and ZnO NPs have great practical importance in industrial applications. CuO NPs is also widely used in biomedical applications as catalyst supports, drug carriers, and gene delivery. However, study conducted on TiO2 NPs have forecast that oxidative DNA damage could be attributed due to reduced glutathione levels with concomitant increase in lipid peroxidation and reactive oxygen species generation. Moreover, there are many evidences showing that ZnO NP and CuO NPs generates ROS production and can cause cell death in different types of cultured cell. Nanoparticle toxicity is assessed by set of tests designed to characterize a given risk and also the mechanism for related outcomes. Conclusively, it becomes more and more important for nanotechnologist to understand the potential health effects of ENPs and what new methodology can be applied to reveal problems like gene silencing and inhibition in antioxidant defense mechanism which can be occurred on severe effects to oxidative stress by ENPs.
Vorheriger Artikel The social responsibility of Nanoscience and Nanotechnology: an integral approach
Nächster Artikel Nanomedicine highlights in atherosclerosis

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Metadaten
Titel
New vision to CuO, ZnO, and TiO2 nanoparticles: their outcome and effects
verfasst von
Sandesh Chibber
Shakeel Ahmed Ansari
Rukhsana Satar
Publikationsdatum
01.04.2013
Verlag
Springer Netherlands
Erschienen in
Journal of Nanoparticle Research / Ausgabe 4/2013
Print ISSN: 1388-0764
Elektronische ISSN: 1572-896X
DOI
https://doi.org/10.1007/s11051-013-1492-x

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