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Quality of Life Research

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17.10.2018

Sex differences in predictors of illness intrusiveness in persons with multiple sclerosis

verfasst von: Lindsay O. Neto, Elizabeth S. Gromisch, Jessica Sloan, Tuula Tyry, Frederick W. Foley

Erschienen in: Quality of Life Research | Ausgabe 2/2019

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Abstract

Purpose

Multiple sclerosis (MS) is a complex, chronic disease that can have debilitating effects on daily activities and well-being, compromising health-related quality of life. One underlying determinant of quality of life (QOL) is perceived illness intrusiveness, which examines the disruptiveness of the condition and/or its related treatment on engagement in interest and activities, in turn affecting psychological functioning. There is evidence that persons with MS (PwMS) have higher level of illness intrusiveness compared to those with other chronic conditions; however, limited research exists on differences by sex. This study aimed to explore these possible differences between men and women, hypothesizing that men with MS will have overall higher illness intrusiveness (lower QOL) when compared to women with MS.

Methods

A total of 922 PwMS were primarily recruited through the North American Research Committee on MS Registry. The participants completed a one-time anonymous online survey. Illness intrusiveness was measured using the Illness Intrusiveness Ratings Scale (IIRS) total score and three subscales. Independent t-tests determined differences in demographics, disease characteristics, and IIRS outcomes. Hierarchical regressions were then used to further assess whether sex was a significant predictor of illness intrusiveness.

Results

Men exhibited greater overall, intimacy, and relationship and personal development-related perceived illness intrusiveness. However, sex was only a significant predictor of the Intimacy IIRS subscale after accounting for age, disability, and depression.

Conclusions

These findings highlight the intrusiveness of MS on intimacy and sexual functioning, particularly among men. Potential clinical implications and future directions are discussed.

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Titel: Sex differences in predictors of illness intrusiveness in persons with multiple sclerosis
verfasst von: Lindsay O. Neto
Elizabeth S. Gromisch
Jessica Sloan
Tuula Tyry
Frederick W. Foley
Publikationsdatum: 17.10.2018
Verlag: Springer International Publishing
Erschienen in: Quality of Life Research / Ausgabe 2/2019
Print ISSN: 0962-9343
Elektronische ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-018-2023-0

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