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Journal of Nanoparticle Research

Erschienen in:

01.06.2015 | Research Paper

Strategies for radiolabeling of commercial TiO₂ nanopowder as a tool for sensitive nanoparticle detection in complex matrices

verfasst von: Heike Hildebrand, Stefan Schymura, Uwe Holzwarth, Neil Gibson, Matteo Dalmiglio, Karsten Franke

Erschienen in: Journal of Nanoparticle Research | Ausgabe 6/2015

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Abstract

Detection and quantification of engineered nanoparticles (NPs) in complex environmental or biological media is a major challenge since NP concentrations are generally expected to be low compared to elemental background levels. This study presents three different options for radiolabeling of commercial titania NP (TiO₂-NP, AEROXIDE^® P25, Evonik Industries, mean diameter 21 nm) for particle detection, localization, and tracing under various experimental conditions. The radiolabeling procedures ensure stability and consistency of important particle properties such as size and morphology. With the presented radiolabeling methods, detection (and quantification) limits for TiO₂-NPs in concentrations as low as 0.5 ng/L can be realized in complex systems without the necessity of intense sample purification or pretreatment.

Vorheriger Artikel Phytotoxicity, uptake, and accumulation of silver with different particle sizes and chemical forms

Nächster Artikel Iron oxide nanoparticles induced alterations in haematological, biochemical and ionoregulatory responses of an Indian major carp Labeo rohita

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In many cell uptake studies exposure times range from several hours to many days or even weeks (Gibson et al. 2011; Marmorato et al. 2011; Simonelli et al. 2011). In such cases the use of short-lived radionuclides that are frequently applied also in medical imaging are of limited use. They can fruitfully only be applied to very fast transport or metabolic mechanisms.

Abbas K et al (2010) Radiolabelling of TiO₂ nanoparticles for radiotracer studies. J Nanopart Res 12:2435–2443. doi:10.1007/s11051-009-9806-8 CrossRef

Abbas K, Simonelli F, Holzwarth U, Cydzik I, Bulgheroni A, Gibson N, Kozempel J (2013) Feasibility study of production of radioactive carbon black or carbon nanotubes in cyclotron facilities for nanobioscience applications. Appl Radiat Isot 73:44–48. doi:10.1016/j.apradiso.2012.11.012 CrossRef

Abramovich S, Guzhovskij B, Zherebcov V, Zvenigorodskij A (1984) Estimated values of total and differential cross sections of proton interactions with nuclei Li-6 and Li-7. Vop At Nauki i Tekhn Ser Yadernye Konstanty 114:17

Butz T (2012) Surface and volume characterization of TiO nanomaterials by Ti time differential perturbed angular correlation. Radiochim Acta 100:147–153. doi:10.1524/ract.2011.1844 CrossRef

Cservenyak I, Kelsall G, Wang W (1996) Reduction of TiIV species in aqueous sulfuric and hydrochloric acid I: titanium speciation. Electrochim Acta 41:563–572CrossRef

Cydzik I, Bilewicz A, Abbas K, Simonelli F, Bulgheroni A, Holzwarth U, Gibson N (2012) A novel method for synthesis of ⁵⁶Co-radiolabelled silica nanoparticles. J Nanopart Res 14(10):1–9. doi:10.1007/s11051-012-1185-x

Gibson N et al (2011) Radiolabelling of engineered nanoparticles for in vitro and in vivo tracing applications using cyclotron accelerators. Arch Toxicol 85:751–773. doi:10.1007/s00204-011-0701-6 CrossRef

Gottschalk F, Kost E, Nowack B (2013a) Engineered nanomaterials in water and soils: a risk quantification based on probabilistic exposure and effect modeling. Environ Toxicol Chem 32:1278–1287. doi:10.1002/etc.2177 CrossRef

Gottschalk F, Sun T, Nowack B (2013b) Environmental concentrations of engineered nanomaterials: review of modeling and analytical studies. Environ Pollut 181:287–300. doi:10.1016/j.envpol.2013.06.003 CrossRef

Hildebrand H, Franke K (2012) A new radiolabeling method for commercial Ag⁰ nanopowder with 110 mAg for sensitive nanoparticle detection in complex media. J Nanopart Res 14(10):1–7. doi:10.1007/s11051-012-1142-8

Holzwarth U et al (2012) Radiolabelling of nanoparticles by proton irradiation: temperature control in nanoparticulate powder targets. J Nanopart Res 14(6):1–15. doi:10.1007/s11051-012-0880-y

Holzwarth U, Bellido E, Dalmiglio M, Kozempel J, Cotogno G, Gibson N (2014) ⁷Be-recoil radiolabelling of industrially manufactured silica nanoparticles. J Nanopart Res 16(9):1–15. doi:10.1007/s11051-014-2574-0

Hu R et al (2010) Neurotoxicological effects and the impairment of spatial recognition memory in mice caused by exposure to TiO₂ nanoparticles. Biomaterials 31:8043–8050. doi:10.1016/j.biomaterials.2010.07.011 CrossRef

Ichedef C et al (2013) Radiochemical synthesis of ^105gAg-labelled silver nanoparticles. J Nanopart Res 15(11):1–13. doi:10.1007/s11051-013-2073-8

Jiang J, Oberdörster G, Biswas P (2009) Characterization of size, surface charge, and agglomeration state of nanoparticle dispersions for toxicological studies. J Nanopart Res 11:77–89. doi:10.1007/s11051-008-9446-4 CrossRef

Keller AA, McFerran S, Lazareva A, Suh S (2013) Global life cycle releases of engineered nanomaterials. J Nanopart Res 15(6):1–17. doi:10.1007/s11051-013-1692-4

Koziara J, Lockman P, Allen D, Mumper R (2003) In situ blood–brain barrier transport of nanoparticles. Pharm Res 20:1772–1778. doi:10.1023/B:PHAM.0000003374.58641.62 CrossRef

Krane K (1987) Introductory nuclear physics. Wiley, New York

Kreyling WG et al (2014) Air-blood barrier translocation of tracheally instilled gold nanoparticles inversely depends on particle size. ACS Nano 8:222–233. doi:10.1021/nn403256v CrossRef

Laycock A, Stolpe B, Römer I, Dybowska A, Valsami-Jones E, Lead JR, Rehkämper M (2014) Synthesis and characterization of isotopically labeled silver nanoparticles for tracing studies. Environ Sci. doi:10.1039/c3en00100h

Lekki J et al (2007) On the follicular pathway of percutaneous uptake of nanoparticles: ion microscopy and autoradiography studies. Nucl Instrum Methods Phys Res Sect B 260:174–177. doi:10.1016/j.nimb.2007.02.021 CrossRef

Marmorato P et al (2011) ⁵⁶Co-labelled radioactive Fe₃O₄ nanoparticles for in vitro uptake studies on Balb/3T3 and Caco-2 cell lines. J Nanopart Res 13:6707–6716. doi:10.1007/s11051-011-0577-7 CrossRef

Möller W et al (2013) Gold nanoparticle aerosols for rodent inhalation and translocation studies. J Nanopart Res 15:1–13. doi:10.1007/s11051-013-1574-9

National Nuclear Data Center (2015) Q-value calculator. Brookhaven National Laboratory, Upton

Neal C, Jarvie H, Rowland P, Lawler A, Sleep D, Scholefield P (2011) Titanium in UK rural, agricultural and urban/industrial rivers: geogenic and anthropogenic colloidal/sub-colloidal sources and the significance of within-river retention. Sci Total Environ 409:1843–1853. doi:10.1016/j.scitotenv.2010.12.021 CrossRef

Ortelli S, Blosi M, Albonetti S, Vaccari A, Dondi M, Costa AL (2013) TiO₂ based nano-photocatalysis immobilized on cellulose substrates. J Photochem Photobiol A 276:58–64. doi:10.1016/j.jphotochem.2013.11.013 CrossRef

Pérez-Campaña C et al (2014) Production of 18F-labeled titanium dioxide nanoparticles by proton irradiation for biodistribution and biological fate studies in rats. Part Part Syst Charact 31:134–142. doi:10.1002/ppsc.201300302 CrossRef

Pfennig G, Klewe-Nebenius H, Seelmann-Eggebert W (1998) Chart of nuclides. Forschungszentrum Karlsruhe, Lage

Podgoršak EB (2006) Radiation physics for medical physicists, vol 1. Springer, Berlin

Rahman IA, Padavettan V (2012) Synthesis of silica nanoparticles by sol–gel: size-dependent properties, surface modification, and applications in silica-polymer nanocomposites—a review. J Nanomater 2012:1–15. doi:10.1155/2012/132424 CrossRef

Sekharan KK, Laumer H, Kern BD, Gabbard F (1976) A neutron detector for measurement of total neutron production cross sections. Nucl Instrum Methods 133:253–257. doi:10.1016/0029-554X(76)90617-0 CrossRef

Sevastinov YG (1974) Method of radioisotope isolation from cyclotron targets. J Radioanal Chem 21:247–257CrossRef

Shultis J, Faw R (2002) Fundamentals of nuclear science and engineering. Marcel Dekker, New YorkCrossRef

Silva BFd, Pérez S, Gardinalli P, Singhal RK, Mozeto AA, Barceló D (2011) Analytical chemistry of metallic nanoparticles in natural environments. TrAC Trends Anal Chem 30:528–540. doi:10.1016/j.trac.2011.01.008 CrossRef

Simonelli F et al (2011) Cyclotron production of radioactive CeO₂ nanoparticles and their application for in vitro uptake studies. IEEE Trans Nanobiosci 10:44–50. doi:10.1109/TNB.2011.2119491 CrossRef

Szélecsényi F et al (2001) Excitation function for the ^natTi(p, x)⁴⁸V nuclear process: evaluation and new measurements for practical applications. Nucl Instrum Methods Phys Res Sect B 174:47–64. doi:10.1016/S0168-583X(00)00516-4 CrossRef

Weir A, Westerhoff P, Fabricius L, Hristovski K, von Goetz N (2012) Titanium dioxide nanoparticles in food and personal care products. Environ Sci Technol 46:2242–2250. doi:10.1021/es204168d CrossRef

Weiss C, Diabate S (2011) A special issue on nanotoxicology. Arch Toxicol 85:705–706. doi:10.1007/s00204-011-0707-0 CrossRef

Zhang R, Bai Y, Zhang B, Chen L, Yan B (2012) The potential health risk of titania nanoparticles. J Hazard Mater 211–212:404–413. doi:10.1016/j.jhazmat.2011.11.022

Ziegler J, Ziegler M, Biersack J (2013) The stopping and range of ions in matter, SRIM-2013.03. http://www.srim.org/#SRIM

Titel: Strategies for radiolabeling of commercial TiO2 nanopowder as a tool for sensitive nanoparticle detection in complex matrices
verfasst von: Heike Hildebrand
Stefan Schymura
Uwe Holzwarth
Neil Gibson
Matteo Dalmiglio
Karsten Franke
Publikationsdatum: 01.06.2015
Verlag: Springer Netherlands
Erschienen in: Journal of Nanoparticle Research / Ausgabe 6/2015
Print ISSN: 1388-0764
Elektronische ISSN: 1572-896X
DOI: https://doi.org/10.1007/s11051-015-3080-8

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