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2018 | OriginalPaper | Buchkapitel

Synthesis of Nitrogen-Containing Heterocycles via Imidoyl or Iminyl Radical Intermediates

verfasst von : Jian Lei, Dengke Li, Qiang Zhu

Erschienen in: Free-Radical Synthesis and Functionalization of Heterocycles

Verlag: Springer International Publishing

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Abstract

Synthesis of nitrogen-containing heterocycles with isocyanides, isothiocyanates, nitriles, imines, oxime derivatives, and other related compounds has been deeply investigated in organic synthesis. This chapter mainly focuses on summarizing radical cyclization reactions of these C-N unsaturated precursors to afford N-heterocycles in the past decade as well as some earlier feature examples. In most cases, imidoyl or iminyl radicals are involved in cyclizing onto unsaturated systems or heteroatoms to generate N-heterocycles, such as phenanthridines, (iso)quinolines, pyridines, indoles, and pyrroles. A few examples via other types of radical intermediates starting from isothiocyanates, isocyanates, and analogous structures are also included.

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Vorheriges Kapitel Reductive Electron Transfer in the Synthesis of Heterocycles

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Titel: Synthesis of Nitrogen-Containing Heterocycles via Imidoyl or Iminyl Radical Intermediates
verfasst von: Jian Lei
Dengke Li
Qiang Zhu
Verlag: Springer International Publishing
Buch: Free-Radical Synthesis and Functionalization of Heterocycles
Print ISBN: 978-3-319-89520-8

Electronic ISBN: 978-3-319-89521-5

Copyright-Jahr: 2018
DOI: https://doi.org/10.1007/7081_2017_9

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