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01.03.2014 | Research Paper

Targeted polymeric nanoparticles containing gold nanorods: a therapeutic approach against glioblastoma

verfasst von: Erica Locatelli, Wolfgang Bost, Marc Fournelle, Jordi Llop, Larraitz Gil, Francesca Arena, Vito Lorusso, Mauro Comes Franchini

Erschienen in: Journal of Nanoparticle Research | Ausgabe 3/2014

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Abstract

Chlorotoxin-targeted polymeric nanoparticles containing entrapped gold nanorods as potential therapeutic agent for glioblastoma multiforme have been developed and evaluated. In first proof of concept experiments, in vitro specific uptake in cancer cells and selective laser-induced cell death have been shown. In vivo studies with optical imaging showed increased retention of targeted NPs in the tumor.

Vorheriger Artikel One-pot template-free fabrication of ZnMn2O4 hollow microspheres as high-performance lithium-ion battery anodes

Nächster Artikel Ambient ultrasonic-assisted synthesis, stepwise growth mechanisms, and photocatalytic activity of flower-like nanostructured ZnO and Ag/ZnO

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Titel: Targeted polymeric nanoparticles containing gold nanorods: a therapeutic approach against glioblastoma
verfasst von: Erica Locatelli
Wolfgang Bost
Marc Fournelle
Jordi Llop
Larraitz Gil
Francesca Arena
Vito Lorusso
Mauro Comes Franchini
Publikationsdatum: 01.03.2014
Verlag: Springer Netherlands
Erschienen in: Journal of Nanoparticle Research / Ausgabe 3/2014
Print ISSN: 1388-0764
Elektronische ISSN: 1572-896X
DOI: https://doi.org/10.1007/s11051-014-2304-7

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