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28.02.2023 | Original Article

Water-ultrastable perovskite CsPbBr₃ nanocrystals for fluorescence-enhanced cellular imaging

verfasst von: Cai-Li He, Zi-Qi Meng, Shu-Xia Ren, Jian Li, Ye Wang, Hao Wu, Hui Bu, Yu Zhang, Wei-Zhong Hao, Shu-Lin Chen, Rong-Rong Yan, Huan Liu, Yu-Fang Zhu, Jin-Jin Zhao

Erschienen in: Rare Metals | Ausgabe 5/2023

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Abstract

Metal halide perovskites have attracted much attention in biomedicine because of their excellent fluorescence energy conversion properties; however, poor water-stability and cytotoxicity limit its applications as a biomedical tracer, especially in cellular imaging. Herein, water-ultrastable perovskites CsPbBr₃:Cs₄PbBr₆ nanocrystals (NCs) encapsulated in chitosan are fabricated successfully using a water-triggered method. The as-synthesized CsPbBr₃:Cs₄PbBr₆@CS (chitosan, CS) nanoparticles in water display enhanced fluorescence emission for 35 days. Further, the viability of glioma cells (U87 cells) incubated with different concentrations of CsPbBr₃:Cs₄PbBr₆@CS nanoparticles (0–20 μg·ml⁻¹) for 24 h is found to be higher than 90%. In artificial body fluid, analyses using laser confocal microscopy, the standard Cell Counting Kit-8 (CCK-8) method, and flow cytometry demonstrated the good water ultrastability and high biocompatibility performance of CsPbBr₃:Cs₄PbBr₆@CS nanoparticles in cellular imaging. Overall, the water-ultrastable halide perovskites support promising perspectives in biological cell tracing and intelligent medical technology.

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Vorheriger Artikel Application of silica-alumina as hydrothermally stable supports for Pt catalysts for acid-assisted soot oxidation

Nächster Artikel Enhanced electromagnetic wave absorption properties of ZIF-67 modified polymer-derived SiCN ceramics by in situ construction of multiple heterointerfaces

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Titel: Water-ultrastable perovskite CsPbBr3 nanocrystals for fluorescence-enhanced cellular imaging
verfasst von: Cai-Li He
Zi-Qi Meng
Shu-Xia Ren
Jian Li
Ye Wang
Hao Wu
Hui Bu
Yu Zhang
Wei-Zhong Hao
Shu-Lin Chen
Rong-Rong Yan
Huan Liu
Yu-Fang Zhu
Jin-Jin Zhao
Publikationsdatum: 28.02.2023
Verlag: Nonferrous Metals Society of China
Erschienen in: Rare Metals / Ausgabe 5/2023
Print ISSN: 1001-0521
Elektronische ISSN: 1867-7185
DOI: https://doi.org/10.1007/s12598-022-02222-8

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Application of silica-alumina as hydrothermally stable supports for Pt catalysts for acid-assisted soot oxidation

Thermal storage properties of Mg with synergistic effect of LaNi and TiH2

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