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Erschienen in:
The Emperor’s New Body: Seeking for a Blueprint of Limb Regeneration in Humans Kapitel lesen Erstes Kapitel lesen

2011 | OriginalPaper | Buchkapitel

Bio-synthetic Encapsulation Systems for Organ Engineering: Focus on Diabetes

verfasst von : Rylie A. Green, Penny J. Martens, Robert Nordon, Laura A. Poole-Warren

Erschienen in: Stem Cell Engineering

Verlag: Springer Berlin Heidelberg

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Abstract

The development of a safe and effective bio-synthetic encapsulation system will potentially improve the treatment of diseases known to benefit from cell implantation therapies. This is of particular importance in the progression towards a permanent treatment for type 1 diabetes. Cell-based therapies for insulin-dependent diabetics ultimately aim to eliminate the need for exogenous insulin through the implantation of donor islet cells or, alternately, stem cells differentiated into glucose-sensitive islet-like cells. Encapsulation devices are required to protect implanted cells from destructive host immune factors. A successful design will be bio-synthetic, having well-defined permeability and providing appropriate biomolecules for physiological functionality and survival of the encapsulated cells.

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Vorheriges Kapitel Stem Cells in Tissue Engineering and Cell Therapies of Urological Defects
Nächstes Kapitel Stem Cell Engineering for Regeneration of Bone Tissue
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Metadaten
Titel
Bio-synthetic Encapsulation Systems for Organ Engineering: Focus on Diabetes
verfasst von
Rylie A. Green
Penny J. Martens
Robert Nordon
Laura A. Poole-Warren
Copyright-Jahr
2011
Verlag
Springer Berlin Heidelberg
Buch
Stem Cell Engineering

Print ISBN: 978-3-642-11864-7

Electronic ISBN: 978-3-642-11865-4

Copyright-Jahr: 2011

DOI
https://doi.org/10.1007/978-3-642-11865-4_16

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