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Erschienen in: Microsystem Technologies 10/2017

20.03.2017 | Technical Paper

Design, fabrication and characterization of 1.0 μm Gap Al based interdigitated electrode for biosensors

verfasst von: R. D. A. A. Rajapaksha, U. Hashim, C. A. N. Fernando

Erschienen in: Microsystem Technologies | Ausgabe 10/2017

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Abstract

Interdigitated electrode (IDE) based electrical biosensors are promising in the medical application field. The aim of the research study is design, fabricate and characterize of low cost, high sensitive biosensor for medical applications. IDE pattern was designed using AutoCAD software with 1 μm finger gap. Fabrication process was done using conventional photolithography process and standard CMOS process. Fabricated electrode was physically characterized using SEM images, electrically validated through I–V measurements and chemically tested with different pH buffer solutions. Al IDE was well fabricated with 0.1 μm tolerance between design mask and fabricated IDEs. Electrical measurements confirmed that IDE was well fabricated without any shortage and results of similar IDE samples were confirmed that the repeatability of the device. The extremely small current variations in nano ampere range were quantitatively detected using extra small volume of 1 μl for different pH buffer solutions. It is confirmed that IDEs are sensitive in both alkali and hydroxyl ions medium.

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Literatur
Zurück zum Zitat Ali ME, Mustafa S, Hashim U, Che Man YB, Foo KL (2012a) Nanobioprobe for the determination of pork adulteration in burger formulations. J Nanomat. doi:10.1155/2012/832387 Ali ME, Mustafa S, Hashim U, Che Man YB, Foo KL (2012a) Nanobioprobe for the determination of pork adulteration in burger formulations. J Nanomat. doi:10.​1155/​2012/​832387
Zurück zum Zitat Ali ME et al (2012b) Species authentication methods in foods and feeds: the present, past, and future of halal forensics. Food Anal Methods 5(5):935–955CrossRef Ali ME et al (2012b) Species authentication methods in foods and feeds: the present, past, and future of halal forensics. Food Anal Methods 5(5):935–955CrossRef
Zurück zum Zitat Barquero-Quirós M, Domínguez-Renedo O, Alonso-Lomillo MA, Arcos-Martínez MJ (2012) Biosensor for aluminium(III) based on its inhibition of α-chymotrypsin immobilized on a screen-printed carbon electrode modified with gold nanoparticles. Microchim Acta 179:65–70CrossRef Barquero-Quirós M, Domínguez-Renedo O, Alonso-Lomillo MA, Arcos-Martínez MJ (2012) Biosensor for aluminium(III) based on its inhibition of α-chymotrypsin immobilized on a screen-printed carbon electrode modified with gold nanoparticles. Microchim Acta 179:65–70CrossRef
Zurück zum Zitat Ding Y, Wang Q, Gao Feng, Gao Fei (2013) Highly sensitive and selective DNA biosensor using a dumbbell-shaped bis-groove binder of bi-acetylferrocene ethylenediamine complex as electrochemical indicator. Electrochim Acta 106:35–42. doi:10.1016/j.electacta.2013.05.066 CrossRef Ding Y, Wang Q, Gao Feng, Gao Fei (2013) Highly sensitive and selective DNA biosensor using a dumbbell-shaped bis-groove binder of bi-acetylferrocene ethylenediamine complex as electrochemical indicator. Electrochim Acta 106:35–42. doi:10.​1016/​j.​electacta.​2013.​05.​066 CrossRef
Zurück zum Zitat Fujimaki M et al (2010) Detection of colored nanomaterials using evanescent field-based waveguide sensors. Opt Express 18(15):15732–15740CrossRef Fujimaki M et al (2010) Detection of colored nanomaterials using evanescent field-based waveguide sensors. Opt Express 18(15):15732–15740CrossRef
Zurück zum Zitat Hashim U, Zaki M, Ayub RM, Azman AH, Adzhri R (2015) Development of Electronic Reader for Formaldehyde Detection Sensor. IEEE International Conference on Biomedical Engineering (ICoBE 2015) 30–31 March 2015 Hashim U, Zaki M, Ayub RM, Azman AH, Adzhri R (2015) Development of Electronic Reader for Formaldehyde Detection Sensor. IEEE International Conference on Biomedical Engineering (ICoBE 2015) 30–31 March 2015
Zurück zum Zitat Lakshmipriya T, Fujimaki M, Gopinath SCB, Awazu K (2013) Generation of anti-influenza aptamers using the systematic evolution of ligands by exponential enrichment for sensing applications. Langmuir 29(48):15107–15115CrossRef Lakshmipriya T, Fujimaki M, Gopinath SCB, Awazu K (2013) Generation of anti-influenza aptamers using the systematic evolution of ligands by exponential enrichment for sensing applications. Langmuir 29(48):15107–15115CrossRef
Zurück zum Zitat Moreno-Hagelsieb L et al (2007) Electrical detection of DNA hybridization: three extraction techniques based on interdigitated Al/Al2O3 capacitors. Biosens Bioelectron 22(9–10):2199–2207CrossRef Moreno-Hagelsieb L et al (2007) Electrical detection of DNA hybridization: three extraction techniques based on interdigitated Al/Al2O3 capacitors. Biosens Bioelectron 22(9–10):2199–2207CrossRef
Zurück zum Zitat Muaz AKM, Hashim U, Liu WW, Ibrahim F, Thong KL, Mohktar MS (2014) Fabrication of interdigitated electrodes (IDE’s) by conventional photolithography technique for pH measurement using micro-gap structure. Biomed Eng Sci (IECBES). doi:10.1109/IECBES.2014.7047474 Muaz AKM, Hashim U, Liu WW, Ibrahim F, Thong KL, Mohktar MS (2014) Fabrication of interdigitated electrodes (IDE’s) by conventional photolithography technique for pH measurement using micro-gap structure. Biomed Eng Sci (IECBES). doi:10.​1109/​IECBES.​2014.​7047474
Zurück zum Zitat Niu S, Sun J, Nan C, Lin J (2013) Sensitive DNA biosensor improved by 1,10-phenanthroline cobalt complex as indicator based on the electrode modified by gold nanoparticles and graphene. Sens Actuators B 176:58–63. doi:10.1016/j.snb.2012.08.085 CrossRef Niu S, Sun J, Nan C, Lin J (2013) Sensitive DNA biosensor improved by 1,10-phenanthroline cobalt complex as indicator based on the electrode modified by gold nanoparticles and graphene. Sens Actuators B 176:58–63. doi:10.​1016/​j.​snb.​2012.​08.​085 CrossRef
Zurück zum Zitat Solanki PR, Kaushik A, Agrawal VV, Malhotra BD (2011) Nanostructured metal oxide-based biosensors. NPG Asia Mat 3(1):17–24CrossRef Solanki PR, Kaushik A, Agrawal VV, Malhotra BD (2011) Nanostructured metal oxide-based biosensors. NPG Asia Mat 3(1):17–24CrossRef
Zurück zum Zitat Wang W et al (2013) Surface modification for protein and DNA immobilization onto GMR biosensor. IEEE Trans Magn 49(1):296–299CrossRef Wang W et al (2013) Surface modification for protein and DNA immobilization onto GMR biosensor. IEEE Trans Magn 49(1):296–299CrossRef
Zurück zum Zitat Wu VCH, Chen S-H, Lin C-S (2007) Real-time detection of Escherichia coli O157:H7 sequences using a circulating-flow system of quartz crystal microbalance. Biosens Bioelectron 22(12):2967–2975CrossRef Wu VCH, Chen S-H, Lin C-S (2007) Real-time detection of Escherichia coli O157:H7 sequences using a circulating-flow system of quartz crystal microbalance. Biosens Bioelectron 22(12):2967–2975CrossRef
Metadaten
Titel
Design, fabrication and characterization of 1.0 μm Gap Al based interdigitated electrode for biosensors
verfasst von
R. D. A. A. Rajapaksha
U. Hashim
C. A. N. Fernando
Publikationsdatum
20.03.2017
Verlag
Springer Berlin Heidelberg
Erschienen in
Microsystem Technologies / Ausgabe 10/2017
Print ISSN: 0946-7076
Elektronische ISSN: 1432-1858
DOI
https://doi.org/10.1007/s00542-017-3373-1

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