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Meccanica

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06.04.2016 | Advances in Biomechanics: from foundations to applications

Effective computational modeling of erythrocyte electro-deformation

verfasst von: Nicola A. Nodargi, Paolo Bisegna, Federica Caselli

Erschienen in: Meccanica | Ausgabe 3/2017

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Abstract

Due to its crucial role in pathophysiology, erythrocyte deformability represents a subject of intense experimental and modeling research. Here a computational approach to electro-deformation for erythrocyte mechanical characterization is presented. Strong points of the proposed strategy are: (1) an accurate computation of the mechanical actions induced on the cell by the electric field, (2) a microstructurally-based continuum model of the erythrocyte mechanical behavior, (3) an original rotation-free shell finite element, especially suited to the application in hand. As proved by the numerical results, the developed tool is effective and sound, and can foster the role of electro-deformation in single-cell mechanical phenotyping.

Vorheriger Artikel On the use of uniaxial tests on the sclera to understand the difference between emmetropic and highly myopic eyes

Nächster Artikel Patient-specific finite element analysis of popliteal stenting

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Titel: Effective computational modeling of erythrocyte electro-deformation
verfasst von: Nicola A. Nodargi
Paolo Bisegna
Federica Caselli
Publikationsdatum: 06.04.2016
Verlag: Springer Netherlands
Erschienen in: Meccanica / Ausgabe 3/2017
Print ISSN: 0025-6455
Elektronische ISSN: 1572-9648
DOI: https://doi.org/10.1007/s11012-016-0424-0

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