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Topics in Catalysis
Erschienen in: Topics in Catalysis 9-12/2024

20.10.2023 | Original Paper

Efficient Detection of Droxidopa in the Presence of Carbidopa Using a Modified Screen-Printed Graphite Electrode

verfasst von: Sayed Ali Ahmadi, Somayeh Tajik

Erschienen in: Topics in Catalysis | Ausgabe 9-12/2024

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Abstract

The determination of pharmaceutical compounds in various samples is considered an effective way to evaluate their effectiveness. Nanomaterials-based electrochemical sensors have proven to offer the desired affordability, portability and high-performance for this purpose. In this work, an electrochemical sensor is described to detect droxidopa in the presence of carbidopa using a screen-printed graphite electrode (SPGE) modified with graphitic carbon nitride (g-C3N4). Admirable electrocatalytic behavior was found for g-C3N4/SPGE towards the droxidopa oxidation, with minimized oxidation overpotential and boosted voltammetric response peak current. Under the optimal circumstances, the peak currents of droxidopa oxidation were proportional to its concentrations (0.15–325.0 µM), with the limit of detection of 0.04 µM. Also, this sensor was applied to detect droxidopa in the presence of carbidopa. The g-C3N4/SPGE successfully resolved the oxidation signals of droxidopa and carbidopa, and the peak separation was calculated to be 310 mV. The g-C3N4/SPGE presented good stability, and repeatability. Finally, the developed g-C3N4/SPGE sensor displayed a satisfactory recovery of the spiked droxidopa and carbidopa in real-sample matrices (tap water and urine).
Vorheriger Artikel Efficient Photocatalytic Degradation of Chlorpyrifos Pesticide from Aquatic Agricultural Waste Using g-C3N4 Decorated Graphene Oxide/V2O5 Nanocomposite
Nächster Artikel Efficient Methane Dry Reforming Process with Low Nickel Loading for Greenhouse Gas Mitigation

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Metadaten
Titel
Efficient Detection of Droxidopa in the Presence of Carbidopa Using a Modified Screen-Printed Graphite Electrode
verfasst von
Sayed Ali Ahmadi
Somayeh Tajik
Publikationsdatum
20.10.2023
Verlag
Springer US
Erschienen in
Topics in Catalysis / Ausgabe 9-12/2024
Print ISSN: 1022-5528
Elektronische ISSN: 1572-9028
DOI
https://doi.org/10.1007/s11244-023-01866-9

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