nach oben

Erschienen in:

2020 | OriginalPaper | Buchkapitel

8. In Vitro Degradation Test of Gd-, Si-Substituted Hydroxyapatite

verfasst von : Elizaveta A. Mukhanova, Ekaterina S. Ivanyutina, Maxim Yu. Stupko, Irina V. Rybal’chenko

Erschienen in: Modeling, Synthesis and Fracture of Advanced Materials for Industrial and Medical Applications

Verlag: Springer International Publishing

Einloggen

Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.

search-config

KI-gestützte Suche

Aus

Abstract

Synthetic hydroxyapatite is involved in osteogenesis when using as an implant. Different substitutions in the hydroxyapatite (HAp) can change the low rate of degradation and solubility of pure hydroxyapatite as well as other physical, chemical, and biological properties. We synthesized single-phase Ca₈Gd₂(PO₄)₄(SiO₄)₂(OH)₂ (Gd, Si-HAp) by coprecipitation and investigated its behavior in model solutions: water, simulated body fluid and physiological saline solution (0.9% NaCl). Morphology of samples before and after degradation confirmed that flake-like crystals of initial Gd, Si-HAp is a preferable form for the further precipitation of HAp crystals with needle-like morphology the same as in human body. The degradation rate of substituted Gd, Si-HAp in comparison with pure HAp is higher in different solutions and the rate of nucleation is apparently slower as we can see in a series of in vitro degradation tests.

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

über 102.000 Bücher
über 537 Zeitschriften

aus folgenden Fachgebieten:

Automobil + Motoren
Bauwesen + Immobilien
Business IT + Informatik
Elektrotechnik + Elektronik
Energie + Nachhaltigkeit
Finance + Banking
Management + Führung
Marketing + Vertrieb
Maschinenbau + Werkstoffe
Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Jetzt informieren

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

über 67.000 Bücher
über 390 Zeitschriften

aus folgenden Fachgebieten:

Automobil + Motoren
Bauwesen + Immobilien
Business IT + Informatik
Elektrotechnik + Elektronik
Energie + Nachhaltigkeit
Maschinenbau + Werkstoffe

Jetzt Wissensvorsprung sichern!

Jetzt informieren

Vorheriges Kapitel Interface Frictional Behaviour of Aluminium and Iron Powder Compacts at Room Temperature

Nächstes Kapitel Mechanical Properties of Microposit S1813 Thin Layers

Dorozhkin, S.V.: Bioceramics of calcium orthophosphates. Biomaterials. 31(7), 1465–1485 (2010)

Adzila S., Murad M., Sopyan I.: Doping metal into calcium phosphate phase for better performance of bone implant materials. Recent Patents Mater. Sci. 5(1), 18–47 (2012)

Balasundaram, G., Webster, T.J.: A perspective on nanophase materials for orthopedic implant applications. J. Mater. Chem. 16(38), 3737 (2006)

Swetha, M., Sahithi, K., Moorthi, A., Srinivasan, N., Ramasamy, K., Selvamurugan, N.: Biocomposites containing natural polymers and hydroxyapatite for bone tissue engineering. Int. J. Biol. Macromol. 47, 1–4 (2010)

Olszta, M.J., Cheng, X., Jee, S.S., Kumar, R., Kim, Y.-Y., Kaufman, M.J., Douglas, E.P., Gower, L.B.: Bone structure and formation: a new perspective. Mater. Sci. Eng. R: Rep. 58(3–5), 77–116 (2007)

Porter, A.E., Patel, N., Skepper, J.N., Best, S.M., Bonfield, W.: Effect of sintered silicate-substituted hydroxyapatite on remodelling processes at the bone–implant interface. Biomaterials 25(16), 3303–3314 (2004)

Marchat, D., Zymelka, M., Coelho, C., Gremillard, L., Joly-pottuz, L., Babonneau, F., Esnouf, C., Chevalier, J., Bernache-assollant, D.: Accurate characterization of pure silicon-substituted hydroxyapatite powders synthesized by a new precipitation route. Acta Biomater. 9(6), 6992–7004 (2013)

Camaioni, A., Cacciotti, I., Campagnolo, L., Bianco, A.: Silicon substituted hydroxyapatite for biomedical applications. In: Mucalo M (ed) Hydroxyapatite for biomedical applications. Woodhead Publishing Elsevier Limited Edition, Oxford, pp 343–373 (2015)

Leventouri, T.: Neutron powder diffraction studies of silicon-substituted hydroxyapatite. Biomaterials 24(23), 4205–4211 (2003)

10.

Arcos, D., Rodríguez-Carvajal, J., Vallet-Regí, M.: Silicon incorporation in hydroxylapatite obtained by controlled crystallization. Chem. Mater. 16(11), 2300–2308 (2004)

11.

Seaborn, C.D., Nielsen, F.H.: Effects of germanium and silicon on bone mineralization. Biol. Trace Elem. Res. 42(2), 151–164 (1994)

12.

Barta, C.A., Sachs-Barrable, K., Jia, J., Thompson, K.H., Wasan, K.M.: Lanthanide containing compounds for therapeutic care in bone resorption disorders. Orvig C

13.

Boanini, E., Gazzano, M., Bigi, A.: Ionic substitutions in calcium phosphates synthesized at low temperature. Acta Biomater. 6, 1882–1894

14.

Li, X., Zeng, H., Teng, L., Chen, H.: Comparative investigation on the crystal structure and cell behavior of rare-earth doped fluorescent apatite nanocrystals. Mater. Lett. 125, 78–81 (2014)

15.

Chen, F., Huang, P., Zhu, Y.J., Wu, J., Zhang,, C.L., Cui, D.X.: The photoluminescence, drug delivery and imaging properties of multifunctional Eu³⁺/Gd³⁺ dual-doped hydroxyapatite nanorods. Biomaterials. 32(34), 9031–9039 (2011)

16.

Liu, Z., Wang, Q., Yao, S., Yang, L., Yu, S., Feng, X., Li, F.: Synthesis and characterization of Tb³⁺/Gd³⁺ dual-doped multifunctional hydroxyapatite nanoparticles. Ceramics Int. 40(2), 2613–2617 (2014)

17.

Yasukawa, A., Kandori, K., Tanaka, H., Gotoh, K.: Preparation and structure of carbonated calcium hydroxyapatite substituted with heavy rare earth ions. Mater. Res. Bull. 47, 1257–1263 (2012)

18.

Yasukawa, A., Gotoh, K., Tanaka, H., Kandori, K.: Preparation and structure of calcium hydroxyapatite substituted with light rare earth ions. Colloids Surf. A : Physicochem. Eng. Asp. 393, 53–59 (2011)

19.

Fleet, M.E., Liu, X., Pan, Y.: Site preference of rare earth elements in hydroxyapatite [Ca10(PO4)6(OH)2]. J. Solid State Chem. 149(2), 391–398 (2000)

20.

Cawthray, J.F., Creagh, A.L., Haynes, C.A., Orvig, C.: Ion exchange in hydroxyapatite with lanthanides. Inorg. Chem. 54(4), 1440–1445 (2015)

21.

Cipreste, M.F., Peres, A.M., Cotta, A.A.C., Aragón, F.H., de Antunes, A.M., Leal, A.S., Macedo, W.A.A., de Sousa, E.M.B.: Synthesis and characterization of 159Gd-doped hydroxyapatite nanorods for bioapplications as theranostic systems. Mater. Chem. Phys. 181, 301–311 (2016)

22.

Li, Y., Ooi, C.P., Philip, Hong Ning, C., Aik Khor, K.: Synthesis and characterization of Neodymium(III) and Gadolinium(III)-Substituted Hydroxyapatite as Biomaterials. Int. J. Appl. Ceram. Technol. 6(4), 501–512 (2009)

23.

Valcheva-Traykova, M., Saso, L., Kostova, I.: Involvement of Lanthanides in the free radicals homeostasis. Curr. Topics Med. Chem. 14(22), 2508–2519 (2014)

24.

Xu, Z.-Q., Mao, X.-J., Jia, L., Xu, J., Zhu, T.-F., Cai, H.-X., Bie, H.-Y., Chen, R.-H., Ma, T.: Synthesis, characterization and anticancer activities of two lanthanide(III) complexes with a nicotinohydrazone ligand. J. Mol. Struct. 1102, 86–90 (2015)

25.

Xu, X., Liu, Q., Xie, Y.: Metal ion-induced stabilization and refolding of anticoagulation factor II from the Venom of Agkistrodon acutus †. Biochemistry 41(11), 3546–3554 (2002)

26.

Mokoena, P.P., Nagpure, I.M., Kumar, V., Kroon, R.E., Olivier, E.J., Neethling, J.H., Swart, H.C., Ntwaeaborwa, O.M.: Enhanced UVB emission and analysis of chemical states of Ca5(PO4)3OH:Gd³⁺, Pr³⁺ phosphor prepared by co-precipitation. J. Phys. Chem. Solids 75(8), 998–1003 (2014)

27.

Madhumathi, K. Sampath Kumar, T.S., Sanjeed, T M.: Silver and gadolinium ions co-substituted hydroxyapatite nanoparticles as bimodal contrast agent for medical imaging. Biocerami. Dev. Appl. 4(2), 1–4 (2014)

28.

Gibson, I.R., Skakle, J., Smith, N., Buckland, T.: Biomedical materials, Patent US20100322867 (23.12.2010)

29.

Yasukawa, A., Kandori, K., Tanaka, H., Gotoh, K.: Preparation and structure of carbonated calcium hydroxyapatite substituted with heavy rare earth ions. Mater. Res. Bull. 47(5), 1257–1263 (2012)

30.

Get’man, E.I., Loboda, S.N., Tkachenko, T.V, Yablochkova, N.V, Chebyshev, K.A.: Isomorphous substitution of samarium and gadolinium for calcium in hydroxyapatite structure. Russ. J. Inorg. Chem. 55(3), 333–338 (2010)

31.

Bohner, M., Lemaitre, J.: Can bioactivity be tested in vitro with SBF solution? Biomaterials 30, 2175–2179 (2009)

32.

Kokubo, T., Takadama, H.: How useful is SBF in predicting in vivo bone bioactivity? Biomaterials 27, 2907–2915 (2006)

33.

Zadpoor, A.A.: Relationship between in vitro apatite-forming ability measured using simulated body fluid and in vivo bioactivity of biomaterials. Mater. Sci. Eng. C. 35(1), 134–143 (2014)

34.

Nayak, A.K.: Hydroxyapatite synthesis methodologies: an overview. Int. J. ChemTech Res. 2(2), 974–4290 (2010)

35.

Christoffersen, J., Christoffersen, M.R., Kjaergaard, N.: The kinetics of dissolution of calcium hydroxyapatite in water at constant pH. J. Cryst. Growth. 43(4), 501–511 (1978)

36.

Okayama, S., Akao, M., Nakamura, S., Shin, Y., Higashikata, M., Aoki, H.: The mechanical properties and solubility of strontium-substituted hydroxyapatite. Bio-Med. Mater. Eng. 1(1), 11–7 (1991)

37.

Chen, Z.F., Darvell, B.W., Leung, V.W.H., Chen, Z.F.: Hydroxyapatite solubility in simple inorganic solutions. Arch. Oral Biol. 49(5), 359–367 (2004)

38.

Kim, S.B., Kim, Y.J., Yoon, T.L., Park, S.A., Cho, I.H., Kim, E.J., Kim, I.A., Shin, J.W.: The characteristics of a hydroxyapatite-chitosan-PMMA bone cement. Biomaterials 25(26), 5715–5723 (2004)

39.

Oyane, A., Kim, H.-M., Furuya, T., Kokubo, T., Miyazaki, T., Nakamura, T.: Preparation and assessment of revised simulated body fluids. J. Biomed. Mater. Res. 65A(2), 188–195 (2003)

40.

Dasgupta, S., Sinha, B.C., Rawat, N.S., Dasgupta, S.: Stepwise complexometric determinations of calcium and magnesium in lime and magnesia bearing materials. Trans. Indian Ceram. Soc. 41(1), 14–16 (2014)

41.

Barge, A., Cravotto, G., Gianolio, E., Fedeli, F.Barge, A.: How to determine free Gd and free ligand in solution of Gd chelates. A technical note. Contrast Media Mol. Imag. 1(5), 184–188 (2006)

42.

Arcos, D., Rodríguez-Carvajal, J., Vallet-Regí, M.: Crystal-chemical characteristics of Silicon–Neodymium substituted hydroxyapatites studied by combined X-ray and neutron powder diffraction. Chem. Mater. 17(1), 57–64 (2005)

43.

Yin, N., Chen, S.Y., Ouyang, Y., Tang, L., Yang, J.X., Wang, H.P.: Biomimetic mineralization synthesis of hydroxyapatite bacterial cellulose nanocomposites. Prog. Nat. Sci.: Mater. Int. 21(6), 472–477 (2011)

44.

Karamian, E., Khandan, A., Eslami, M., Gheisari, H., Rafiaei, N.: Investigation of HA nanocrystallite size crystallographic characterizations in NHA, BHA and HA pure powders and their influence on biodegradation of HA. Adv. Mater. Res. 829, 314–318 (2013)

45.

Wang, H.X., Guan, S.K., Wang, X., Ren, C.X., Wang, L.G.: In vitro degradation and mechanical integrity of Mg-Zn-Ca alloy coated with Ca-deficient hydroxyapatite by the pulse electrodeposition process. Acta Biomater. 6(5), 1743–1748 (2010)

46.

Jongwattanapisan, P., Charoenphandhu, N., Krishnamra, N., Thongbunchoo, J., Tang, I.M., Hoonsawat,, R., Smith, S.M., Pon-On,, W.: In vitro study of the SBF and osteoblast-like cells on hydroxyapatite/ chitosan-silica nanocomposite. Mater. Sci. Eng. C 31(2), 290–299 (2011)

47.

Ferraz, M.P., Monteiro, F.J., Manuel, C.M.: Hydroxyapatite nanoparticles : a review of preparation methodologies. J. Appl. Biomater. 2(2), 74–80 (2004)

48.

Dorozhkin, S.V.: A review on the dissolution models of calcium apatites. Prog. Cryst. Growth Charact. Mater. 44(1), 45–61 (2002)

49.

Bengtsson, A., Sjöberg, S.: Surface complexation and proton-promoted dissolution in aqueous apatite systems. Pure Appl. Chem. 81(9), 1569–1584 (2009)

50.

Shikina, N.D., Zotov, A.V, Volchenkova, V.A.: The solubility of Gd(2)Ti(2)O(7) and the hydrolysis of Gd(3+) in acidic solutions at 250A degrees C and saturation vapor pressure. Geochem. Int. 47(4), 372–379 (2009)

51.

Hayakawa, S., Kanaya, T., Tsuru, K., Shirosaki, Y., Osaka, A., Fujii, E., Kawabata,, K., Gasqueres, G., Bonhomme, C., Babonneau, F., Jäger, C., Kleebe, H.-J.: Heterogeneous structure and in vitro degradation behavior of wet-chemically derived nanocrystalline silicon-containing hydroxyapatite particles. Acta Biomater. 9(1), 4856–4867 (2013)

52.

Rootare, H.M., Deitz, V.R., Carpenter, F.G.: Solubility product phenomena in hydroxyapatite-water systems. J. Colloid Sci. 17(3), 179–206 (1962)

53.

Branda F., Arcobello-Varlese, F., Costantini, A., Luciani, G.: Effect of the substitution of M2O3 (M = La, Y, In, Ga, Al) for CaO on the bioactivity of 2.5CaO·2SiO2 glass. Biomaterials 23(3), 711–716 (2002)

54.

Taylor, D. Fracture and repair of bone: a multiscale problem. J. Mater. Sci. 42(21), 8911–8918 (2007)

Titel: In Vitro Degradation Test of Gd-, Si-Substituted Hydroxyapatite
verfasst von: Elizaveta A. Mukhanova
Ekaterina S. Ivanyutina
Maxim Yu. Stupko
Irina V. Rybal’chenko
Verlag: Springer International Publishing
Buch: Modeling, Synthesis and Fracture of Advanced Materials for Industrial and Medical Applications
Print ISBN: 978-3-030-48160-5

Electronic ISBN: 978-3-030-48161-2

Copyright-Jahr: 2020
DOI: https://doi.org/10.1007/978-3-030-48161-2_8

Premium Partner

Marktübersichten

Die im Laufe eines Jahres in der „adhäsion“ veröffentlichten Marktübersichten helfen Anwendern verschiedenster Branchen, sich einen gezielten Überblick über Lieferantenangebote zu verschaffen.

Zur Marktübersicht