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Journal of Materials Science
Erschienen in: Journal of Materials Science 10/2016

10.02.2016 | Review

A review of carbon dots in biological applications

verfasst von: Jilong Wang, Jingjing Qiu

Erschienen in: Journal of Materials Science | Ausgabe 10/2016

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Abstract

Luminescent carbon-based nanomaterials have inspired tremendous research interests due to their tunable optical properties as well as superior biocompatibility. In this review, distinct light emission properties of carbon dots (CDs) derived from different synthesis methods are summarized. The optical properties of as-synthesized CDs can be further controlled by element doping and surface functionalization of CDs for tunable band gap. Due to their low cytotoxicity and tunable optical behaviors, luminescent CDs have been extensively studied for their potential biomedical applications, such as analytical sensors, and bioimaging devices. This review presents a comprehensive overview of the emerging luminescent CDs and their applications as biosensors and bioimaging agents. The challenges and perspectives in the near future are also discussed.
Vorheriger Artikel Wet chemical synthesis of rare earth-doped barium titanate nanoparticles
Nächster Artikel Self-templated formation of tremella-like MoS2 with expanded spacing of (002) crystal planes for Li-ion batteries

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Literatur
1.
Guldi DM, Illescas BM, Atienza CM, Wielopolskia M, Martin N (2009) Fullerene for organic electronics. Chem Soc Rev 38:1587–1597CrossRef
2.
Liu J, Rinzler AG, Dai H et al (1998) Fullerene pipes. Science 280:1253–1256CrossRef
3.
Barbot A, Di Bin C, Lucas B, Ratier B, Aldissi M (2013) N-type doping and thermoelectric properties of co-sublimed cesium-carbonate-doped fullerene. J Mater Sci 48:2785–2789. doi:10.​1007/​s10853-012-6824-1 CrossRef
4.
Sall M, Monnet I, Moisy F et al (2015) Track formation in III-N semiconductors irradiated by swift heavy ions and fullerene and re-evaluation of the inelastic thermal spike model. J Mater Sci 50:5214–5227. doi:10.​1007/​s10853-015-9069-y CrossRef
5.
Malgas GF, Motaung DE, Arendse CJ (2012) Temperature-dependence on the optical properties and the phase separation of polymer–fullerene thin films. J Mater Sci 47:4282–4289. doi:10.​1007/​s10853-012-6278-5 CrossRef
6.
Laraoui A, Meriles CA (2013) Approach to dark spin cooling in a diamond nanocrystal. ACS Nano 7:3403–3410CrossRef
7.
Laraoui A, Hodges JS, Meriles CA (2012) Nitrogen-vacancy-assisted magnetometry of paramagnetic centers in an individual diamond nanocrystal. Nano Lett 12:3477–3482CrossRef
8.
Yu M, George C, Cao Y, Wootton D, Zhou J (2014) Microstructure, corrosion, and mechanical properties of compression-molded zinc-nanodiamond composites. J Mater Sci 49:3629–3641. doi:10.​1007/​s10853-014-8066-x CrossRef
9.
Borjanović V, Bistričić L, Pucić I et al (2016) Proton-radiation resistance of poly (ethylene terephthalate)–nanodiamond–graphene nanoplatelet nanocomposites. J Mater Sci 51:1000–1016. doi:10.​1007/​s10853-015-9431-0 CrossRef
10.
Hola K, Bourlinos AB, Kozak O et al (2014) Photoluminescence effects of graphitic core size and surface functional groups in carbon dots: COO- induced red-shift emission. Carbon 70:279–286CrossRef
11.
Yu XJ, Liu JJ, Yu YC, Zuo SL, Li BS (2014) Preparation and visible light photocatalytic activity of carbon quantum dots/TiO2 nanosheet composites. Carbon 68:718–724CrossRef
12.
Hu LM, Sun Y, Li SL et al (2014) Multifunctional carbon dots with high quantum yield for imaging and gene delivery. Carbon 67:508–513CrossRef
13.
14.
Xu Q, Zhao J, Liu Y et al (2015) Enhancing the luminescence of carbon dots by doping nitrogen element and its application in the detection of Fe(III). J Mater Sci 50:2571–2576. doi:10.​1007/​s10853-015-8822-6 CrossRef
15.
De Volder MFL, Tawfick SH, Baughman RH, Hart AJ (2013) Carbon nanotubes: present and future commercial applications. Science 339:535–539CrossRef
16.
Wang Z, Yin L, Zhang M et al (2014) Synthesis and characterization of Ag3PO4/multiwalled carbon nanotube composite photocatalyst with enhanced photocatalytic activity and stability under visible light. J Mater Sci 49:1585–1593. doi:10.​1007/​s10853-013-7841-4 CrossRef
17.
18.
Tang P, Zhang R, Shi R, Bin Y (2015) Synergetic effects of carbon nanotubes and carbon fibers on electrical and self-heating properties of high-density polyethylene composites. J Mater Sci 50:1565–1574. doi:10.​1007/​s10853-014-8716-z CrossRef
19.
20.
Zubair M, Mustafa M, Ali A, Doh YH, Choi KH (2015) Improvement of solution based conjugate polymer organic light emitting diode by ZnO–graphene quantum dots. J Mater Sci: Mater Electron 26:3344–3351. doi:10.​1007/​s10854-015-2837-2
21.
Liu M, He L, Liu X, Liu C, Luo S (2014) Reduced graphene oxide and CdTe nanoparticles co-decorated TiO2 nanotube array as a visible light photocatalyst. J Mater Sci 49:2263–2269. doi:10.​1007/​s10853-013-7922-4 CrossRef
22.
Wang X, Pei Y, Lu M, Lu X, Du X (2015) Highly efficient adsorption of heavy metals from wastewaters by graphene oxide-ordered mesoporous silica materials. J Mater Sci 50:2113–2121. doi:10.​1007/​s10853-014-8773-3 CrossRef
23.
Su S, Wang J, Wei J, Martínez-Zaguilán R, Qiu J, Wang S (2015) Efficient photothermal therapy of brain cancer through porphyrin functionalized graphene oxide. New J Chem 39:5743–5749CrossRef
24.
Wang J, Qiu J (2015) Luminescent graphene quantum dots: as emerging fluorescent materials for biological application. Sci Adv Mater 7:1979–1989CrossRef
25.
Georgakilas V, Perman JA, Tucek J, Zboril R (2015) Broad family of carbon nanoallotropes: classification, chemistry, and applications of fullerenes, carbon dots, nanotubes, graphene, nanodiamonds, and combined superstructures. Chem Rev 115:4744–4822CrossRef
26.
Cao L, Wang X, Meziani MJ et al (2007) Carbon dots for multiphoton bioimaging. J Am Chem Soc 129:11318–11319CrossRef
27.
Yang ST, Cao L, Luo PGJ et al (2009) Carbon dots for optical imaging in vivo. J Am Chem Soc 131:11308–11309CrossRef
28.
Tian L, Ghosh D, Chen W, Pradhan S, Chang XJ, Chen SW (2009) Nanosized carbon particles from natural gas soot. Chem Mater 21:2803–2809CrossRef
29.
Zhao QL, Zhang ZL, Huang BH, Peng J, Zhang M, Pang DW (2008) Facile preparation of low cytotoxicity fluorescent carbon nanocrystals by electrooxidation of graphite. Chem Commun 41:5116–5118CrossRef
30.
Ray SC, Saha A, Jana NR, Sarkar R (2009) Fluorescent carbon nanoparticles: synthesis, characterization, and bioimaging application. J Phys Chem C 113:18546–18551CrossRef
31.
Zhou JG, Zhou XT, Li RY et al (2009) Electronic structure and luminescence center of blue luminescent carbon nanocrystals. Chem Phys Lett 474:320–324CrossRef
32.
Baker SN, Baker GA (2010) Luminescent carbon nanodots: emergent nanolights. Angew Chem Int Ed 49:6726–6744CrossRef
33.
Zhang ZP, Zhang J, Chen N, Qu LT (2012) Graphene quantum dots: an emerging material for energy-related applications and beyond. Energy Environ Sci 5:8869–8890CrossRef
34.
Shen JH, Zhu YH, Yang XL, Zong J, Zhang JM, Li CZ (2012) One-pot hydrothermal synthesis of graphene quantum dots surface-passivated by polyethylene glycol and their photoelectric conversion under near-infrared light. New J Chem 36:97–101CrossRef
35.
Zhou XJ, Zhang Y, Wang C et al (2012) Photo-fenton reaction of graphene oxide: a new strategy to prepare graphene quantum dots for DNA cleavage. ACS Nano 6:6592–6599CrossRef
36.
Wang J, Wei J, Su S, Qiu J (2015) Novel fluorescence resonance energy transfer optical sensors for vitamin B 12 detection using thermally reduced carbon dots. New J Chem 39:501–507CrossRef
37.
Li Q, Ohulchanskyy TY, Liu R et al (2010) Photoluminescent carbon dots as biocompatible nanoprobes for targeting cancer cells in vitro. J Phys Chem C 114:12062–12068CrossRef
38.
Liu C, Zhang P, Zhai X et al (2012) Nano-carrier for gene delivery and bioimaging based on carbon dots with PEI-passivation enhanced fluorescence. Biomaterials 33:3604–3613CrossRef
39.
Milosavljevic V, Nguyen HV, Michalek P et al (2015) Synthesis of carbon quantum dots for DNA labeling and its electrochemical, fluorescent and electrophoretic characterization. Chem Pap 69:192–201CrossRef
40.
Xu XY, Ray R, Gu YL et al (2004) Electrophoretic analysis and purification of fluorescent single-walled carbon nanotube fragments. J Am Chem Soc 126:12736–12737CrossRef
41.
Zheng L, Chi Y, Dong Y, Lin J, Wang B (2009) Electrochemiluminescence of water-soluble carbon nanocrystals released electrochemically from graphite. J Am Chem Soc 131:4564–4565CrossRef
42.
Li H, Ming H, Liu Y et al (2011) Fluorescent carbon nanoparticles: electrochemical synthesis and their pH sensitive photoluminescence properties. New J Chem 35:2666–2670CrossRef
43.
Hou YX, Lu QJ, Deng JH, Li HT, Zhang YY (2015) One-pot electrochemical synthesis of functionalized fluorescent carbon dots and their selective sensing for mercury ion. Anal Chim Acta 866:69–74CrossRef
44.
Liu R, Wu D, Liu S, Koynov K, Knoll W, Li Q (2009) An aqueous route to multicolor photoluminescent carbon dots using silica spheres as carriers. Agnew Chem 121:4668–4671CrossRef
45.
Lai C-W, Hsiao Y-H, Peng Y-K, Chou P-T (2012) Facile synthesis of highly emissive carbon dots from pyrolysis of glycerol; gram scale production of carbon dots/mSiO 2 for cell imaging and drug release. J Mater Chem 22:14403–14409CrossRef
46.
Yang Y, Wu D, Han S, Hu P, Liu R (2013) Bottom-up fabrication of photoluminescent carbon dots with uniform morphology via a soft–hard template approach. Chem Commun 49:4920–4922CrossRef
47.
Li SH, Wang LY, Chusuei CC et al (2015) Nontoxic carbon dots potently inhibit human insulin fibrillation. Chem Mater 27:1764–1771CrossRef
48.
Kasibabu BSB, D’souza SL, Jha S, Singhal RK, Basu H, Kailasa SK (2015) One-step synthesis of fluorescent carbon dots for imaging bacterial and fungal cells. Anal Method 7:2373–2378CrossRef
49.
Dong YQ, Pang HC, Yang HB et al (2013) Carbon-based dots co-doped with nitrogen and sulfur for high quantum yield and excitation-independent emission. Angew Chem Int Ed 52:7800–7804CrossRef
50.
Wu ZL, Zhang P, Gao MX et al (2013) One-pot hydrothermal synthesis of highly luminescent nitrogen-doped amphoteric carbon dots for bioimaging from Bombyx mori silk–natural proteins. J Mater Chem B 1:2868–2873CrossRef
51.
Jin XZ, Sun XB, Chen G et al (2015) pH-sensitive carbon dots for the visualization of regulation of intracellular pH inside living pathogenic fungal cells. Carbon 81:388–395CrossRef
52.
Zheng XG, Wang HL, Gong Q et al (2015) Highly luminescent carbon nanoparticles as yellow emission conversion phosphors. Mater Lett 143:290–293CrossRef
53.
Xu Q, Pu P, Zhao JG et al (2015) Preparation of highly photoluminescent sulfur-doped carbon dots for Fe(III) detection. J Mater Chem A 3:542–546CrossRef
54.
Xu JY, Zhou Y, Cheng GF, Dong MT, Liu SX, Huang CB (2015) Carbon dots as a luminescence sensor for ultrasensitive detection of phosphate and their bioimaging properties. Luminescence 30:411–415CrossRef
55.
Tong GS, Wang JX, Wang RB et al (2015) Amorphous carbon dots with high two-photon fluorescence for cellular imaging passivated by hyperbranched poly(amino amine). J Mater Chem B 3:700–706CrossRef
56.
Wang B, Tang W, Lu H, Huang Z (2015) Hydrothermal synthesis of ionic liquid-capped carbon quantum dots with high thermal stability and anion responsiveness. J Mater Sci 50:5411–5418. doi:10.​1007/​s10853-015-9085-y CrossRef
57.
Liu H, Ye T, Mao C (2007) Fluorescent carbon nanoparticles derived from candle soot. Angew Chem Int Ed 46:6473–6475CrossRef
58.
Peng H, Travas-Sejdic J (2009) Simple aqueous solution route to luminescent carbogenic dots from carbohydrates. Chem Mater 21:5563–5565CrossRef
59.
Zhang J, Yuan Y, Liang G, Yu SH (2015) Scale-up synthesis of fragrant nitrogen-doped carbon dots from bee pollens for bioimaging and catalysis. Adv Sci 2
60.
Zhu H, Wang X, Li Y, Wang Z, Yang F, Yang X (2009) Microwave synthesis of fluorescent carbon nanoparticles with electrochemiluminescence properties. Chem Commun 34:5118–5120CrossRef
61.
Wang X, Qu K, Xu B, Ren J, Qu X (2011) Microwave assisted one-step green synthesis of cell-permeable multicolor photoluminescent carbon dots without surface passivation reagents. J Mater Chem 21:2445–2450CrossRef
62.
Mitra S, Chandra S, Kundu T, Banerjee R, Pramanik P, Goswami A (2012) Rapid microwave synthesis of fluorescent hydrophobic carbon dots. RSC Adv 2:12129–12131CrossRef
63.
Zhang LL, Han YJ, Zhu JB, Zhai YL, Dong SJ (2015) Simple and sensitive fluorescent and electrochemical trinitrotoluene sensors based on aqueous carbon dots. Anal Chem 87:2033–2036CrossRef
64.
Lopez C, Zougagh M, Algarra M et al (2015) Microwave-assisted synthesis of carbon dots and its potential as analysis of four heterocyclic aromatic amines. Talanta 132:845–850CrossRef
65.
Chen L, Li YN, Gu W (2015) Synthesis of carbon dots by microwave pyrolysis of polyol in the presence of inorganic ions. Nanosci Nanotechnol Lett 7:6–9CrossRef
66.
Dong YJ, Su M, Chen PY, Sun HW (2015) Chemiluminescence of carbon dots induced by diperiodato-nicklate (IV) in alkaline solution and its application to a quenchometric flow-injection assays of paracetamol, l-cysteine and glutathione. Microchim Acta 182:1071–1077CrossRef
67.
Li L, Yu B, You T (2015) Nitrogen and sulfur CO-doped carbon dots for highly selective and sensitive detection of Hg (II) Ions. Biosens Bioelectron 74:263–269CrossRef
68.
Li X, Wang H, Shimizu Y, Pyatenko A, Kawaguchi K, Koshizaki N (2010) Preparation of carbon quantum dots with tunable photoluminescence by rapid laser passivation in ordinary organic solvents. Chem Commun 47:932–934CrossRef
69.
Jiang H, Chen F, Lagally MG, Denes FS (2009) New strategy for synthesis and functionalization of carbon nanoparticles. Langmuir 26:1991–1995CrossRef
70.
Tao HQ, Yang K, Ma Z et al (2012) In vivo NIR fluorescence imaging, biodistribution, and toxicology of photoluminescent carbon dots produced from carbon nanotubes and graphite. Small 8:281–290CrossRef
71.
Bottini M, Balasubramanian C, Dawson MI, Bergamaschi A, Bellucci S, Mustelin T (2006) Isolation and characterization of fluorescent nanoparticles from pristine and oxidized electric arc-produced single-walled carbon nanotubes. J Phys Chem B 110:831–836CrossRef
72.
Wang Q, Zheng H, Long Y, Zhang L, Gao M, Bai W (2011) Microwave–hydrothermal synthesis of fluorescent carbon dots from graphite oxide. Carbon 49:3134–3140CrossRef
73.
Zhang XY, Wang SQ, Zhu CY et al (2013) Carbon-dots derived from nanodiamond: photoluminescence tunable nanoparticles for cell imaging. J Colloid Interface Sci 397:39–44CrossRef
74.
Qiao Z-A, Wang Y, Gao Y et al (2009) Commercially activated carbon as the source for producing multicolor photoluminescent carbon dots by chemical oxidation. Chem Commun 46:8812–8814CrossRef
75.
Bourlinos AB, Stassinopoulos A, Anglos D, Zboril R, Karakassides M, Giannelis EP (2008) Surface functionalized carbogenic quantum dots. Small 4:455–458CrossRef
76.
Bourlinos AB, Stassinopoulos A, Anglos D, Zboril R, Georgakilas V, Giannelis EP (2008) Photoluminescent carbogenic dots. Chem Mater 20:4539–4541CrossRef
77.
Wang JL, Su SH, Wei JH et al (2015) Ratio-metric sensor to detect riboflavin via fluorescence resonance energy transfer with ultrahigh sensitivity. Physica E 72:17–24CrossRef
78.
Jahan S, Mansoor F, Naz S, Lei J, Kanwal S (2013) Oxidative synthesis of highly fluorescent boron/nitrogen co-doped carbon nanodots enabling detection of photosensitizer and carcinogenic dye. Anal Chem 85:10232–10239CrossRef
79.
Shen P, Xia Y (2014) Synthesis-modification integration: one-step fabrication of boronic acid functionalized carbon dots for fluorescent blood sugar sensing. Anal Chem 86:5323–5329CrossRef
80.
Xue W, Lin Z, Chen H, Lu C, Lin J-M (2011) Enhancement of ultraweak chemiluminescence from reaction of hydrogen peroxide and bisulfite by water-soluble carbon nanodots. J Phys Chem C 115:21707–21714CrossRef
81.
Li HT, He XD, Liu Y et al (2011) One-step ultrasonic synthesis of water-soluble carbon nanoparticles with excellent photoluminescent properties. Carbon 49:605–609CrossRef
82.
Yang ZC, Wang M, Yong AM et al (2011) Intrinsically fluorescent carbon dots with tunable emission derived from hydrothermal treatment of glucose in the presence of monopotassium phosphate. Chem Commun 47:11615–11617CrossRef
83.
Ma Z, Ming H, Huang H, Liu Y, Kang Z (2012) One-step ultrasonic synthesis of fluorescent N-doped carbon dots from glucose and their visible-light sensitive photocatalytic ability. New J Chem 36:861–864CrossRef
84.
Hu S, Tian R, Dong Y, Yang J, Liu J, Chang Q (2013) Modulation and effects of surface groups on photoluminescence and photocatalytic activity of carbon dots. Nanoscale 5:11665–11671CrossRef
85.
86.
Sk MP, Chattopadhyay A (2014) Induction coil heater prepared highly fluorescent carbon dots as invisible ink and explosive sensor. RSC Adv 4:31994–31999CrossRef
87.
Sahu S, Behera B, Maiti TK, Mohapatra S (2012) Simple one-step synthesis of highly luminescent carbon dots from orange juice: application as excellent bio-imaging agents. Chem Commun 48:8835–8837CrossRef
88.
De B, Karak N (2013) A green and facile approach for the synthesis of water soluble fluorescent carbon dots from banana juice. RSC Adv 3:8286–8290CrossRef
89.
Zhu C, Zhai J, Dong S (2012) Bifunctional fluorescent carbon nanodots: green synthesis via soy milk and application as metal-free electrocatalysts for oxygen reduction. Chem Commun 48:9367–9369CrossRef
90.
Kenneth N (2013) Versatility with carbon dots–from overcooked BBQ to brightly fluorescent agents and photocatalysts. RSC Adv 3:15604–15607CrossRef
91.
Liao H, Jiang C, Liu W et al (2015) Fluorescent nanoparticles from several commercial beverages: their properties and potential application for bioimaging. J Agric Food Chem 63:8527–8533CrossRef
92.
Jiang C, Wu H, Song X, Ma X, Wang J, Tan M (2014) Presence of photoluminescent carbon dots in Nescafe® original instant coffee: applications to bioimaging. Talanta 127:68–74CrossRef
93.
Wang Z, Liao H, Wu H, Wang B, Zhao H, Tan M (2015) Fluorescent carbon dots from beer for breast cancer cell imaging and drug delivery. Anal Method 7:8911–8917CrossRef
94.
Wang J, Wang CF, Chen S (2012) Amphiphilic egg-derived carbon dots: rapid plasma fabrication, pyrolysis process, and multicolor printing patterns. Agnew Chem 124:9431–9435CrossRef
95.
Sk MP, Jaiswal A, Paul A, Ghosh SS, Chattopadhyay A (2012) Presence of amorphous carbon nanoparticles in food caramels. Sci Rep 2
96.
England MW, Patil AJ, Mann S (2015) Synthesis and confinement of carbon dots in lysozyme single crystals produces ordered hybrid materials with tuneable luminescence. Chem Eur J 21:9008–9013CrossRef
97.
Xu Z-Q, Yang L-Y, Fan X-Y et al (2014) Low temperature synthesis of highly stable phosphate functionalized two color carbon nanodots and their application in cell imaging. Carbon 66:351–360CrossRef
98.
Liu S, Tian J, Wang L et al (2012) Hydrothermal treatment of grass: a low-cost, green route to nitrogen-doped, carbon-rich, photoluminescent polymer nanodots as an effective fluorescent sensing platform for label-free detection of Cu (II) ions. Adv Mater 24:2037–2041CrossRef
99.
Kargbo O, Jin Y, Ding S-N (2015) Recent advances in luminescent carbon dots. Curr Anal Chem 11:4–21CrossRef
100.
Zhao A, Chen Z, Zhao C, Gao N, Ren J, Qu X (2015) Recent advances in bioapplications of C-dots. Carbon 85:309–327CrossRef
101.
Li HT, Kang ZH, Liu Y, Lee ST (2012) Carbon nanodots: synthesis, properties and applications. J Mater Chem 22:24230–24253CrossRef
102.
Dong YQ, Li GL, Zhou NN, Wang RX, Chi YW, Chen GN (2012) Graphene quantum dot as a green and facile sensor for free chlorine in drinking water. Anal Chem 84:8378–8382CrossRef
103.
Bourlinos AB, Zboril R, Petr J, Bakandritsos A, Krysmann M, Giannelis EP (2012) Luminescent surface quaternized carbon dots. Chem Mater 24:6–8CrossRef
104.
Wang W, Cheng L, Liu WG (2014) Biological applications of carbon dots. Sci China Chem 57:522–539CrossRef
105.
Li HT, He XD, Kang ZH et al (2010) Water-soluble fluorescent carbon quantum dots and photocatalyst design. Angew Chem Int Ed 49:4430–4434CrossRef
106.
Pan DY, Zhang JC, Li Z, Wu C, Yan XM, Wu MH (2010) Observation of pH-, solvent-, spin-, and excitation-dependent blue photoluminescence from carbon nanoparticles. Chem Commun 46:3681–3683CrossRef
107.
Jiang K, Sun S, Zhang L et al (2015) Red, green, and blue luminescence by carbon dots: full-color emission tuning and multicolor cellular imaging. Angew Chem Int Ed 54:5360–5363CrossRef
108.
Wang X, Cao L, Yang ST et al (2010) Bandgap-like strong fluorescence in functionalized carbon nanoparticles. Angew Chem Int Ed 49:5310–5314CrossRef
109.
Bourlinos AB, Trivizas G, Karakassides MA et al (2015) Green and simple route toward boron doped carbon dots with significantly enhanced non-linear optical properties. Carbon 83:173–179CrossRef
110.
Wei WL, Xu C, Wu L, Wang JS, Ren JS, Qu XG (2014) Non-enzymatic-browning-reaction: a versatile route for production of nitrogen-doped carbon dots with tunable multicolor luminescent display. Sci Rep 4
111.
Qian ZS, Ma J, Shan X, Feng H, Shao L, Chen J (2014) Highly luminescent N-doped carbon quantum dots as an effective multifunctional fluorescence sensing platform (vol 20, pg 254, 2014). Chem Eur J 20:2983CrossRef
112.
Zhai XY, Zhang P, Liu CJ et al (2012) Highly luminescent carbon nanodots by microwave-assisted pyrolysis. Chem Commun 48:7955–7957CrossRef
113.
Jiang J, He Y, Li SY, Cui H (2012) Amino acids as the source for producing carbon nanodots: microwave assisted one-step synthesis, intrinsic photoluminescence property and intense chemiluminescence enhancement. Chem Commun 48:9634–9636CrossRef
114.
Zhuo Y, Miao H, Zhong D, Zhu SS, Yang XM (2015) One-step synthesis of high quantum-yield and excitation-independent emission carbon dots for cell imaging. Mater Lett 139:197–200CrossRef
115.
Sun YP, Wang X, Lu FS et al (2008) Doped carbon nanoparticles as a new platform for highly photoluminescent dots. J Phys Chem C 112:18295–18298CrossRef
116.
Anilkumar P, Wang X, Cao L et al (2011) Toward quantitatively fluorescent carbon-based “quantum’’ dots. Nanoscale 3:2023–2027CrossRef
117.
Wang F, Pang SP, Wang L, Li Q, Kreiter M, Liu CY (2010) One-step synthesis of highly luminescent carbon dots in noncoordinating solvents. Chem Mater 22:4528–4530CrossRef
118.
Wang F, Xie Z, Zhang H, Liu CY, Zhang YG (2011) Highly luminescent organosilane-functionalized carbon dots. Adv Funct Mater 21:1027–1031CrossRef
119.
Kong WQ, Liu J, Liu RH et al (2014) Quantitative and real-time effects of carbon quantum dots on single living HeLa cell membrane permeability. Nanoscale 6:5116–5120CrossRef
120.
Zhu SJ, Wang L, Zhou N et al (2014) The crosslink enhanced emission (CEE) in non-conjugated polymer dots: from the photoluminescence mechanism to the cellular uptake mechanism and internalization. Chem Commun 50:13845–13848CrossRef
121.
Yang ST, Wang X, Wang HF et al (2009) Carbon dots as nontoxic and high-performance fluorescence imaging agents. J Phys Chem C 113:18110–18114CrossRef
122.
Bhirde AA, Patel V, Gavard J et al (2009) Targeted killing of cancer cells in vivo and in vitro with EGF-directed carbon nanotube-based drug delivery. ACS Nano 3:307–316CrossRef
123.
Wang YL, Anilkumar P, Cao L et al (2011) Carbon dots of different composition and surface functionalization: cytotoxicity issues relevant to fluorescence cell imaging. Exp Biol Med 236:1231–1238CrossRef
124.
Huang XL, Zhang F, Zhu L et al (2013) Effect of injection routes on the biodistribution, clearance, and tumor uptake of carbon dots. ACS Nano 7:5684–5693CrossRef
125.
Li N, Liang XF, Wang LL et al (2012) Biodistribution study of carbogenic dots in cells and in vivo for optical imaging. J Nanopart Res 14:1–9
126.
Zhou L, Lin YH, Huang ZZ, Ren JS, Qu XG (2012) Carbon nanodots as fluorescence probes for rapid, sensitive, and label-free detection of Hg2 + and biothiols in complex matrices. Chem Commun 48:1147–1149CrossRef
127.
Qu KG, Wang JS, Ren JS, Qu XG (2013) Carbon dots prepared by hydrothermal treatment of dopamine as an effective fluorescent sensing platform for the label-free detection of iron(III) ions and dopamine. Chem Eur J 19:7243–7249CrossRef
128.
Lu WB, Qin XY, Liu S et al (2012) Economical, green synthesis of fluorescent carbon nanoparticles and their use as probes for sensitive and selective detection of mercury(II) ions. Anal Chem 84:5351–5357CrossRef
129.
Zhao AD, Zhao CQ, Li M, Ren JS, Qu XG (2014) Ionic liquids as precursors for highly luminescent, surface-different nitrogen-doped carbon dots used for label-free detection of Cu2 +/Fe3 + and cell imaging. Anal Chim Acta 809:128–133CrossRef
130.
Salinas-Castillo A, Ariza-Avidad M, Pritz C et al (2013) Carbon dots for copper detection with down and upconversion fluorescent properties as excitation sources. Chem Commun 49:1103–1105CrossRef
131.
Wei WL, Xu C, Ren JS, Xu BL, Qu XG (2012) Sensing metal ions with ion selectivity of a crown ether and fluorescence resonance energy transfer between carbon dots and graphene. Chem Commun 48:1284–1286CrossRef
132.
Gupta A, Chaudhary A, Mehta P et al (2015) Nitrogen doped thiol functionalized carbon dots for ultrasensitive Hg(II) detection. Chem Commun 51:10750–10753CrossRef
133.
Wang C, Wang C, Xu P, Li A, Chen Y, Zhuo K (2016) Synthesis of cellulose-derived carbon dots using acidic ionic liquid as a catalyst and its application for detection of Hg2+. J Mater Sci 51:861–867. doi:10.​1007/​s10853-015-9410-5 CrossRef
134.
Cui X, Zhu L, Wu J et al (2015) A fluorescent biosensor based on carbon dots-labeled oligodeoxyribonucleotide and graphene oxide for mercury (II) detection. Biosens Bioelectron 63:506–512CrossRef
135.
Kong B, Zhu AW, Ding CQ, Zhao XM, Li B, Tian Y (2012) Carbon dot-based inorganic-organic nanosystem for two-photon imaging and biosensing of pH variation in living cells and tissues. Adv Mater 24:5844–5848CrossRef
136.
Li HL, Zhang YW, Wang L, Tian JQ, Sun XP (2011) Nucleic acid detection using carbon nanoparticles as a fluorescent sensing platform. Chem Commun 47:961–963CrossRef
137.
Noh EH, Ko HY, Lee CH, Jeong MS, Chang YW, Kim S (2013) Carbon nanodot-based self-delivering microRNA sensor to visualize microRNA124a expression during neurogenesis. J Mater Chem B 1:4438–4445CrossRef
138.
Maiti S, Das K, Das PK (2013) Label-free fluorimetric detection of histone using quaternized carbon dot-DNA nanobiohybrid. Chem Commun 49:8851–8853CrossRef
139.
Yu CM, Li XZ, Zeng F, Zheng FY, Wu SZ (2013) Carbon-dot-based ratiometric fluorescent sensor for detecting hydrogen sulfide in aqueous media and inside live cells. Chem Commun 49:403–405CrossRef
140.
Zhu AW, Qu Q, Shao XL, Kong B, Tian Y (2012) Carbon-dot-based dual-emission nanohybrid produces a ratiometric fluorescent sensor for in vivo imaging of cellular copper ions. Angew Chem Int Ed 51:7185–7189CrossRef
141.
Lei JY, Yang LG, Lu DL et al (2015) Carbon dot-incorporated PMO nanoparticles as versatile platforms for the design of ratiometric sensors, multichannel traceable drug delivery vehicles, and efficient photocatalysts. Adv Opt Mater 3:57–63CrossRef
142.
Gao X, Ding CQ, Zhu AW, Tian Y (2014) Carbon-dot-based ratiometric fluorescent probe for imaging and biosensing of superoxide anion in live cells. Anal Chem 86:7071–7078CrossRef
143.
Jana J, Ganguly M, Pal T (2015) Intriguing cysteine induced improvement of the emissive property of carbon dots with sensing applications. Phys Chem Chem Phys 17:2394–2403CrossRef
144.
Deng JH, Lu QJ, Hou YX et al (2015) Nanosensor composed of nitrogen-doped carbon dots and gold nanoparticles for highly selective detection of cysteine with multiple signals. Anal Chem 87:2195–2203CrossRef
145.
Ni P, Dai H, Li Z et al (2015) Carbon dots based fluorescent sensor for sensitive determination of hydroquinone. Talanta 144:258–262CrossRef
146.
Bhaisare ML, Pandey S, Khan MS, Talib A, Wu HF (2015) Fluorophotometric determination of critical micelle concentration (CMC) of ionic and non-ionic surfactants with carbon dots via Stokes shift. Talanta 132:572–578CrossRef
147.
Luo PJG, Sahu S, Yang ST et al (2013) Carbon “quantum” dots for optical bioimaging. J Mater Chem B 1:2116–2127CrossRef
148.
Goh EJ, Kim KS, Kim YR et al (2012) Bioimaging of hyaluronic acid derivatives using nanosized carbon dots. Biomacromolecules 13:2554–2561CrossRef
149.
Hsu PC, Shih ZY, Lee CH, Chang HT (2012) Synthesis and analytical applications of photoluminescent carbon nanodots. Green Chem 14:917–920CrossRef
150.
Sun YP, Zhou B, Lin Y et al (2006) Quantum-sized carbon dots for bright and colorful photoluminescence. J Am Chem Soc 128:7756–7757CrossRef
151.
Wei JM, Zhang X, Sheng YZ et al (2014) Simple one-step synthesis of water-soluble fluorescent carbon dots from waste paper. New J Chem 38:906–909CrossRef
152.
Zhu SJ, Meng QN, Wang L et al (2013) Highly Photoluminescent Carbon Dots for Multicolor Patterning, Sensors, and Bioimaging. Angew Chem Int Ed 52:3953–3957CrossRef
153.
Liu J, Liu XL, Luo HJ, Gao YF (2014) One-step preparation of nitrogen-doped and surface-passivated carbon quantum dots with high quantum yield and excellent optical properties. Rsc Adv 4:7648–7654CrossRef
154.
Wang J, Zhang P, Huang C, Liu G, Leung KC-F, Wang Y-XJ (2015) High performance photoluminescent carbon dots for in vitro and in vivo bioimaging: effect of nitrogen doping ratios. Langmuir 31:8063–8073CrossRef
155.
Jia XF, Li J, Wang EK (2012) One-pot green synthesis of optically pH-sensitive carbon dots with upconversion luminescence. Nanoscale 4:5572–5575CrossRef
156.
Zong J, Zhu YH, Yang XL, Shen JH, Li CZ (2011) Synthesis of photoluminescent carbogenic dots using mesoporous silica spheres as nanoreactors. Chem Commun 47:764–766CrossRef
Metadaten
Titel
A review of carbon dots in biological applications
verfasst von
Jilong Wang
Jingjing Qiu
Publikationsdatum
10.02.2016
Verlag
Springer US
Erschienen in
Journal of Materials Science / Ausgabe 10/2016
Print ISSN: 0022-2461
Elektronische ISSN: 1573-4803
DOI
https://doi.org/10.1007/s10853-016-9797-7

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