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01.08.2014 | Research Paper

A polymer encapsulation approach to prepare zwitterion-like, biocompatible quantum dots with wide pH and ionic stability

verfasst von: Liming Huang, Mingxia Liao, Siqi Chen, Violeta G. Demillo, Sally A. Dupre, Xiaoshan Zhu, Nelson G. Publicover, Kenneth W. Hunter Jr

Erschienen in: Journal of Nanoparticle Research | Ausgabe 8/2014

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Abstract

A surface modification approach adopting polymer encapsulation was developed to prepare zwitterion-like quantum dots (ZWL-QDs). The fundamental physical, chemical, and biological properties of the ZWL-QDs were characterized. It is found that the ZWL-QDs almost preserve the quantum yield (QY) of native hydrophobic QDs in organic solvents, and also are compact in size (7 ~ 10 nm hydrodynamic diameter) and stable over wide pHs or in high salinity solutions. Further cellular study shows that the ZWL-QDs with a concentration less than 100 nM have a minimal cytotoxicity and thus are biocompatible. Characterizing and understanding these essential properties of the ZWL-QDs are an important step before employing them for various applications.

Vorheriger Artikel The inclusion into PLGA nanoparticles enables α-bisabolol to efficiently inhibit the human dendritic cell pro-inflammatory activity

Nächster Artikel Surface functionalization of microwave plasma-synthesized silica nanoparticles for enhancing the stability of dispersions

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Titel: A polymer encapsulation approach to prepare zwitterion-like, biocompatible quantum dots with wide pH and ionic stability
verfasst von: Liming Huang
Mingxia Liao
Siqi Chen
Violeta G. Demillo
Sally A. Dupre
Xiaoshan Zhu
Nelson G. Publicover
Kenneth W. Hunter Jr
Publikationsdatum: 01.08.2014
Verlag: Springer Netherlands
Erschienen in: Journal of Nanoparticle Research / Ausgabe 8/2014
Print ISSN: 1388-0764
Elektronische ISSN: 1572-896X
DOI: https://doi.org/10.1007/s11051-014-2555-3

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