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Quality of Life Research

Erschienen in:

24.06.2016

Association of circulating 25-hydroxyvitamin D with mental well-being in a population-based, nationally representative sample of German adolescents

verfasst von: Theresa Katharina Schäfer, Christoph Herrmann-Lingen, Thomas Meyer

Erschienen in: Quality of Life Research | Ausgabe 12/2016

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Abstract

Objective

Numerous studies have linked vitamin D to health-related quality of life (hrQoL) in chronically ill adults or elderly subjects. The aim of this study was to evaluate the association between 25-hydroxyvitamin D (25(OH)D) and hrQoL in a population-based sample of German adolescents.

Methods

A total of n = 5066 study participants from the nationwide, representative German Health Interview and Examination Survey for Children and Adolescents (Kinder- und Jugendgesundheitssurvey) aged 11–17 years were included in this post hoc analysis. HrQoL was measured using the well-validated self- and parent-rated Children’s Quality of Life questionnaires (KINDL-R), while the level of distress was assessed using the self- and proxy version of the Strengths and Difficulties Questionnaire (SDQ). Serum 25(OH)D concentrations were determined using a commercially available chemiluminescence immunoassay.

Results

Bivariate analyses demonstrated a significant positive association between 25(OH)D and hrQoL for both self- [estimate (E) = 0.82, 95 % confidence interval (95 % CI) 0.35–1.30, p = 0.001] and parent ratings (E = 1.33, 95 % CI 0.83–1.83, p < 0.001). In addition, we found negative correlations between 25(OH)D and self- (E = −0.34, 95 % CI −0.58 to −0.11, p = 0.005) and parent-reported total SDQ scores (E = −0.70, 95 % CI −1.03 to −0.37, p < 0.001). Generalized linear models adjusted for age, sex, body mass index, systolic blood pressure, migration background, socio-economic status, and sedentary screen time confirmed that 25(OH)D independently and significantly predicted better hrQoL (p ≤ 0.004).

Conclusions

These findings linking 25(OH)D to better well-being in a nationally representative sample of German children and adolescents suggest beneficial effects of vitamin D on mental health. However, recommendations for vitamin supplementation in healthy children and adolescents are not warranted from our data.

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Buell, J. S., Scott, T. M., Dawson-Hughes, B., Dallal, G. E., Rosenberg, I. H., Folstein, M. F., et al. (2009). Vitamin D is associated with cognitive function in elders receiving home health services. Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 64, 888–895.CrossRef

Llewellyn, D. J., Langa, K. M., & Lang, I. A. (2009). Serum 25-hydroxyvitamin D concentration and cognitive impairment. Journal of Geriatric Psychiatry and Neurology, 22, 188–195.CrossRefPubMed

Annweiler, C., Schott, A. M., Allali, G., Bridenbaugh, S. A., Kressig, R. W., Allain, P., et al. (2010). Association of vitamin D deficiency with cognitive impairment in older women: Cross-sectional study. Neurology, 74, 27–32.CrossRefPubMed

Ganji, V., Milone, C., Cody, M. M., McCarty, F., & Wang, Y. T. (2010). Serum vitamin D concentrations are related to depression in young adult US population: The Third National Health and Nutrition Examination Survey. International Archives of Medicine, 3, 29.CrossRefPubMedPubMedCentral

Hoang, M. T., Defina, L. F., Willis, B. L., Leonard, D. S., Weiner, M. F., & Brown, E. S. (2011). Association between low serum 25-hydroxyvitamin D and depression in a large sample of healthy adults: The Cooper Center longitudinal study. Mayo Clinic Proceedings, 86, 1050–1055.CrossRefPubMedPubMedCentral

Maddock, J., Berry, D. J., Geoffroy, M.-C., Power, C., & Hyppönen, E. (2013). Vitamin D and common mental disorders in mid-life: Cross-sectional and prospective findings. Clinical Nutrition, 32, 758–764.CrossRefPubMed

Pan, A., Lu, L., Franco, O. H., Yu, Z., Li, H., & Lin, X. (2009). Association between depressive symptoms and 25-hydroxyvitamin D in middle-aged and elderly Chinese. Journal of Affective Disorders, 118, 240–243.CrossRefPubMed

Almeida, O. P., Hankey, G. J., Yeap, B. B., Golledge, J., & Flicker, L. (2015). Vitamin D concentration and its association with past, current and future depression in older men: The Health in Men Study. Maturitas, 81, 36–41.CrossRefPubMed

Dana-Alamdari, L., Kheirouri, S., & Noorazar, S. G. (2015). Serum 25-hydroxyvitamin D in patients with major depressive disorder. Iranian Journal of Public Health, 44, 690–697.PubMedPubMedCentral

10.

Sakalli, H., Arslan, D., & Yucel, A. E. (2012). The effect of oral and parenteral vitamin D supplementation in the elderly: A prospective, double-blinded, randomized, placebo-controlled study. Rheumatology International, 32, 2279–2283.CrossRefPubMed

11.

Jorde, R., Sneve, M., Figenschau, Y., Svartberg, J., & Waterloo, K. (2008). Effects of vitamin D supplementation on symptoms of depression in overweight and obese subjects: Randomized double blind trial. Journal of Internal Medicine, 264, 599–609.CrossRefPubMed

12.

Hoffmann, M. R., Senior, P. A., & Mager, D. R. (2015). Vitamin D supplementation and health-related quality of life: A systematic review of the literature. Journal of the Academy of Nutrition and Dietetics, 115, 406–418.CrossRef

13.

Ataie-Jafari, A., Qorbani, M., Heshmat, R., Ardalan, G., Motlagh, M. E., Asayesh, H., et al. (2015). The association of vitamin D deficiency with psychiatric distress and violence behaviors in Iranian adolescents: The CASPIAN-III study. Journal of Diabetes and Metabolic Disorders, 14, 62.CrossRefPubMedPubMedCentral

14.

Tolppanen, A. M., Sayers, A., Fraser, W. D., Lewis, G., Zammit, S., & Lawlor, D. A. (2012). The association of 25-hydroxyvitamin D3 and D2 with behavioural problems in childhood. PLoS One, 7, e40097.CrossRefPubMedPubMedCentral

15.

Hölling, H., Kamtsiuris, P., Lange, M., Thierfelder, W., Thamm, M., & Schlack, R. (2007). The German Health Interview and Examination Survey for Children and Adolescents (KiGGS): Study management and conduct of fieldwork. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 50, 557–566.CrossRefPubMed

16.

Kamtsiuris, P., Lange, M., & Schaffrath Rosario, A. (2007). The German Health Interview and Examination Survey for Children and Adolescents (KiGGS): Sample design, response and nonresponse analysis. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 50, 547–556.CrossRefPubMed

17.

Neuhauser, H., & Thamm, M. (2007). Blood pressure measurement in the German Health Interview and Examination Survey for Children and Adolescents (KiGGS). Methodology and initial results. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 50, 728–735.CrossRefPubMed

18.

Schenk, L., Ellert, U., & Neuhauser, H. (2007). Children and adolescents in Germany with a migration background. Methodical aspects in the German Health Interview and Examination Survey for Children and Adolescents (KiGGS). Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 50, 590–599.CrossRefPubMed

19.

Hintzpeter, B., Scheidt-Nave, C., Müller, M. J., Schenk, L., & Mensink, G. B. (2008). Higher prevalence of vitamin D deficiency is associated with immigrant background among children and adolescents in Germany. Journal of Nutrition, 138, 1482–1490.PubMed

20.

Winkler, J., & Stolzenberg, H. (1999). Social class index in the Federal Health Survey. Gesundheitswesen, 61, S178–S183.PubMed

21.

Lange, M., Kamtsiuris, P., Lange, C., Schaffrath Rosario, A., Stolzenberg, H., & Lampert, T. (2007). Sociodemographic characteristics in the German Health Interview and Examination Survey for Children and Adolescents (KiGGS)—Operationalisation and public health significance, taking as an example the assessment of general state of health. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 50, 578–589.CrossRefPubMed

22.

Thierfelder, W., Roth, H.-J., Laussmann, D., Pientka, L., Schumacher, J., Schulz, J., et al. (2008). Vitamin D and parathyroid hormone: A tool to determine assay-specific cutoff values for vitamin D. Journal of Laboratory Medicine, 32, 456–463.

23.

Souberbielle, J.-C., Fayol, V., Sault, C., Lawson-Body, E., Kahan, A., & Cormier, C. (2005). Assay-specific decision limits for two new automated parathyroid hormone and 25-hydroxyvitamin D assays. Clinical Chemistry, 51, 395–400.CrossRefPubMed

24.

Wallace, A. M., Gibson, S., de la Hunty, A., Lamberg-Allardt, C., & Ashwell, M. (2010). Measurement of 25-hydroxyvitamin D in the clinical laboratory: Current procedures, performance characteristics and limitations. Steroids, 75, 477–488.CrossRefPubMed

25.

Ravens-Sieberer, U., & Bullinger, M. (1998). Assessing health-related quality of life in chronically ill children with the German KINDL: First psychometric and content analytical results. Quality of Life Research, 7, 399–407.CrossRefPubMed

26.

Ravens-Sieberer, U., Ellert, U., & Erhart, M. (2007). Health-related quality of life of children and adolescents in Germany. Norm data from the German Health Interview and Examination Survey (KiGGS). Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 50, 810–818.CrossRefPubMed

27.

Ellert, U., Ravens-Sieberer, U., Erhart, M., & Kurth, B. M. (2011). Determinants of agreement between self-reported and parent-assessed quality of life for children in Germany-results of the German Health Interview and Examination Survey for Children and Adolescents (KiGGS). Health and Quality of Life Outcomes, 9, 102.CrossRefPubMedPubMedCentral

28.

Goodman, R. (1997). The Strengths and Difficulties Questionnaire: A research note. Journal of Child Psychology and Psychiatry, 38, 581–586.CrossRefPubMed

29.

Becker, A., Hagenberg, N., Roessner, V., Woerner, W., & Rothenberger, A. (2004). Evaluation of the self-reported SDQ in a clinical setting: Do self-reports tell us more than ratings by adult informants? European Child and Adolescent Psychiatry, 13, SII17–SII24.CrossRef

30.

Becker, A., Woerner, W., Hasselhorn, M., Banaschewski, T., & Rothenberger, A. (2004). Validation of the parent and teacher SDQ in a clinical sample. European Child and Adolescent Psychiatry, 13, SII11–SII16.

31.

Rothenberger, A., Becker, A., Erhart, M., Wille, N., Ravens-Sieberer, U., & BELLA study group. (2008). Psychometric properties of the parent strengths and difficulties questionnaire in the general population of German children and adolescents: Results of the BELLA study. European Child and Adolescent Psychiatry, 2008, S99–S105.CrossRef

32.

Goodman, A., & Goodman, R. (2009). Strengths and Difficulties Questionnaire as a dimensional measure of child mental health. Journal of the American Academy of Child and Adolescent Psychiatry, 48, 400–403.CrossRefPubMed

33.

Raczkiewicz, A., Kisiel, B., Kulig, M., & Tłustochowicz, W. (2015). Vitamin D status and its association with quality of life, physical activity, and disease activity in rheumatoid arthritis patients. Journal of Clinical Rheumatology, 21, 126–130.CrossRefPubMed

34.

Jaddou, H. Y., Batieha, A. M., Khader, Y. S., Kanaan, S. H., El-Khateeb, M. S., & Ajlouni, K. M. (2012). Depression is associated with low levels of 25-hydroxyvitamin D among Jordanian adults: Results from a national population survey. European Archives of Psychiatry and Clinical Neuroscience, 262, 321–327.CrossRefPubMed

35.

Le Goaziou, M. F., Kellou, N., Flori, M., Perdrix, C., Dupraz, C., Bodier, E., et al. (2014). Vitamin D supplementation for diffuse musculoskeletal pain: Results of a before-and-after study. The European Journal of General Practice, 20, 3–9.CrossRefPubMed

36.

Huang, W., Shah, S., Long, Q., Crankshaw, A. K., & Tangpricha, V. (2013). Improvement of pain, sleep, and quality of life in chronic pain patients with vitamin D supplementation. Clinical Journal of Pain, 29, 341–347.CrossRefPubMed

37.

Motsinger, S., Lazovich, D., MacLehose, R. F., Torkelson, C. J., & Robien, K. (2012). Vitamin D intake and mental health-related quality of life in older women: The Iowa Women’s Health Study. Maturitas, 71, 267–273.CrossRefPubMed

38.

McGrath, J., Scragg, R., Chant, D., Eyles, D., Burne, T., & Obradovic, D. (2007). No association between serum 25-hydroxyvitamin D3 level and performance on psychometric tests in NHANES III. Neuroepidemiology, 29, 49–54.CrossRefPubMed

39.

Slinin, Y., Paudel, M. L., Taylor, B. C., Fink, H. A., Ishani, A., Canales, M. T., et al. (2010). 25-Hydroxyvitamin D levels and cognitive performance and decline in elderly men. Neurology, 74, 33–41.CrossRefPubMedPubMedCentral

40.

Buell, J. S., Dawson-Hughes, B., Scott, T. M., Weiner, D. E., Dallal, G. E., Qui, W. Q., et al. (2010). 25-Hydroxyvitamin D, dementia, and cerebrovascular pathology in elders receiving home services. Neurology, 74, 18–26.CrossRefPubMedPubMedCentral

41.

Bener, A., Kamal, M., Bener, H. Z., & Bhugra, D. (2014). Higher prevalence of iron deficiency as strong predictor of attention deficit hyperactivity disorder in children. Annals of Medical and Health Sciences Research, 4, S291–S297.CrossRefPubMedPubMedCentral

42.

Goksugur, S. B., Tufan, A. E., Semiz, M., Gunes, C., Bekdas, M., Tosun, M., et al. (2014). Vitamin D status in children with attention-deficit-hyperactivity disorder. Pediatrics International, 56, 515–519.CrossRefPubMed

43.

Kamal, M., Bener, A., & Ehlayel, M. S. (2014). Is high prevalence of vitamin D deficiency a correlate for attention deficit hyperactivity disorder? Attention Deficit and Hyperactivity Disorders, 6, 73–78.CrossRefPubMed

44.

Alhraiwil, N. J., Ali, A., Househ, M. S., Al-Shehri, A. M., & El-Metwally, A. A. (2015). Systematic review of the epidemiology of attention deficit hyperactivity disorder in Arab countries. Neurosciences (Riyadh), 20, 137–144.CrossRef

45.

Féron, F., Burne, T. H., Brown, J., Smith, E., McGrath, J. J., Mackay-Sim, A., et al. (2005). Developmental vitamin D3 deficiency alters the adult rat brain. Brain Research Bulletin, 65, 141–148.CrossRefPubMed

46.

Bianco, J., Gueye, Y., Marqueste, T., Alluin, O., Risso, J.-J., Garcia, S., et al. (2011). Vitamin D₃ improves respiratory adjustment to fatigue and H-reflex responses in paraplegic adult rats. Neuroscience, 188, 182–192.CrossRefPubMed

47.

Langub, M. C., Herman, J. P., Malluche, H. H., & Koszewski, N. J. (2001). Evidence of functional vitamin D receptors in rat hippocampus. Neuroscience, 104, 49–56.CrossRefPubMed

48.

Small, S. A., Schobel, S. A., Buxton, R. B., Witter, M. P., & Barnes, C. A. (2011). A pathophysiological framework of hippocampal dysfunction in ageing and disease. Nature Reviews Neuroscience, 12, 585–601.CrossRefPubMedPubMedCentral

49.

Obradovic, D., Gronemeyer, H., Lutz, B., & Rein, T. (2006). Cross-talk of vitamin D and glucocorticoids in hippocampal cells. Journal of Neurochemistry, 96, 500–509.CrossRefPubMed

50.

Patrick, R. P., & Ames, B. N. (2014). Vitamin D hormone regulates serotonin synthesis. Part 1: Relevance for autism. The FASEB Journal, 28, 2398–2413.CrossRefPubMed

51.

Kaneko, I., Sabir, M. S., Dussik, C. M., Whitfield, G. K., Karrys, A., Hsieh, J.-C., et al. (2015). 1,25-Dihydroxyvitamin D regulates expression of the tryptophan hydroxylase 2 and leptin genes: Implication for behavioral influences of vitamin D. The FASEB Journal, 29, 4023–4035.CrossRefPubMed

Titel: Association of circulating 25-hydroxyvitamin D with mental well-being in a population-based, nationally representative sample of German adolescents
verfasst von: Theresa Katharina Schäfer
Christoph Herrmann-Lingen
Thomas Meyer
Publikationsdatum: 24.06.2016
Verlag: Springer International Publishing
Erschienen in: Quality of Life Research / Ausgabe 12/2016
Print ISSN: 0962-9343
Elektronische ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-016-1334-2

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