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Erschienen in: Journal of Applied Mathematics and Computing 1-2/2020

11.09.2019 | Original Research

Global stability for an age-structured multistrain virus dynamics model with humoral immunity

verfasst von: Tsuyoshi Kajiwara, Toru Sasaki, Yoji Otani

Erschienen in: Journal of Applied Mathematics and Computing | Ausgabe 1-2/2020

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Abstract

In this paper, we present an age-structured multistrain mathematical model for infectious disease in vivo with infection age of cells. The model considers strain specific immune variables and the effect of absorption of pathogens into uninfected cells. By the construction of a Lyapunov functional, we prove the global stability results of the model, and show that several strains can survive at an equilibrium. We present full mathematical details of the proof of the global stability. The proof contains persistence arguments.

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Metadaten
Titel
Global stability for an age-structured multistrain virus dynamics model with humoral immunity
verfasst von
Tsuyoshi Kajiwara
Toru Sasaki
Yoji Otani
Publikationsdatum
11.09.2019
Verlag
Springer Berlin Heidelberg
Erschienen in
Journal of Applied Mathematics and Computing / Ausgabe 1-2/2020
Print ISSN: 1598-5865
Elektronische ISSN: 1865-2085
DOI
https://doi.org/10.1007/s12190-019-01283-w

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