Skip to main content
Erschienen in: Microsystem Technologies 8/2011

01.08.2011 | Technical Paper

Multilayer high-aspect-ratio RF coil for NMR applications

verfasst von: C. Y. Hsieh, Y. T. Yeh, L. S. Fan

Erschienen in: Microsystem Technologies | Ausgabe 8/2011

Einloggen

Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.

search-config
loading …

Abstract

Microcoils offer a high degree of mass sensitivity and high magnetic field gradient strength in magnetic resonance microscopy applications. This paper presents a novel multilayer high-aspect-ratio metal fabrication process that can be used to fabricate a nanoliter-volume radio frequency (RF) saddle coil with an embedded flow-through fluidic channel for nuclear magnetic resonance (NMR) applications. The fabrication process is based on repeated electroplating processes and structure release processes. The achieved aspect ratio of the developed RF saddle coil is 4 with a structure line width of 25 μm. The resistance of the RF coil and the 1H spectrum line width have been measured and are found to be 0.7 Ω and 350 Hz, respectively. Our results indicate that this novel fabrication process for RF microcoils is feasible for NMR applications.

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

  • über 102.000 Bücher
  • über 537 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Finance + Banking
  • Management + Führung
  • Marketing + Vertrieb
  • Maschinenbau + Werkstoffe
  • Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

  • über 67.000 Bücher
  • über 390 Zeitschriften

aus folgenden Fachgebieten:

  • Automobil + Motoren
  • Bauwesen + Immobilien
  • Business IT + Informatik
  • Elektrotechnik + Elektronik
  • Energie + Nachhaltigkeit
  • Maschinenbau + Werkstoffe




 

Jetzt Wissensvorsprung sichern!

Literatur
Zurück zum Zitat Badilita V, Kratt K, Baxan N, Mohmmadzadeh M, Burger T, Weber H, von Elverfeldt D, Hennig J, Korvink JG, Wallrabe U (2010) On-chip three dimensional microcoils for MRI at the microscale. Lab Chip 10:1387–1390CrossRef Badilita V, Kratt K, Baxan N, Mohmmadzadeh M, Burger T, Weber H, von Elverfeldt D, Hennig J, Korvink JG, Wallrabe U (2010) On-chip three dimensional microcoils for MRI at the microscale. Lab Chip 10:1387–1390CrossRef
Zurück zum Zitat Bu M, Melvin T, Ensell GJ, Wilkinson JS, Evans AGR (2004) A new masking technology for deep glass etching and its microfluidic application. Sens Actuators A Phys 115:476–482CrossRef Bu M, Melvin T, Ensell GJ, Wilkinson JS, Evans AGR (2004) A new masking technology for deep glass etching and its microfluidic application. Sens Actuators A Phys 115:476–482CrossRef
Zurück zum Zitat Demas V, Herberg JL, Malba V, Bernhardt A, Evans L, Harvey C, Chinn SC, Maxwell RS, Reimer J (2007) Portable, low-cost NMR with laser-lathe lithography produced microcoils. J Magn Reson 189:121–129CrossRef Demas V, Herberg JL, Malba V, Bernhardt A, Evans L, Harvey C, Chinn SC, Maxwell RS, Reimer J (2007) Portable, low-cost NMR with laser-lathe lithography produced microcoils. J Magn Reson 189:121–129CrossRef
Zurück zum Zitat Ehrmann K, Saillen N, Vincent F, Stettler M, Jordan M, Wurm FM, Besse P-A, Popovic R (2007) Microfabricated solenoids and Helmholtz coils for NMR spectroscopy of mammalian cells. Lab Chip 7:373–380CrossRef Ehrmann K, Saillen N, Vincent F, Stettler M, Jordan M, Wurm FM, Besse P-A, Popovic R (2007) Microfabricated solenoids and Helmholtz coils for NMR spectroscopy of mammalian cells. Lab Chip 7:373–380CrossRef
Zurück zum Zitat Ginsberg DM, Melchner MJ (1970) Optimum geometry of saddle shaped coils for generating a uniform magnetic field. Rev Sci Instrum 41:122–123CrossRef Ginsberg DM, Melchner MJ (1970) Optimum geometry of saddle shaped coils for generating a uniform magnetic field. Rev Sci Instrum 41:122–123CrossRef
Zurück zum Zitat Goto S, Matsunaga T, Matsuoka Y, Kuroda K, Esashi M, Haga Y (2007) Development of high-resolution intraluminal and intravascular MRI probe using microfabrication on cylindrical substrates. In: IEEE MEMS 2007, Kobe, Japan, 21–25 January 2007, pp 329–332 Goto S, Matsunaga T, Matsuoka Y, Kuroda K, Esashi M, Haga Y (2007) Development of high-resolution intraluminal and intravascular MRI probe using microfabrication on cylindrical substrates. In: IEEE MEMS 2007, Kobe, Japan, 21–25 January 2007, pp 329–332
Zurück zum Zitat Iliescu C, Jing J, Tay FEH, Miao J, Sun T (2005) Characterization of masking layers for deep wet etching of glass in an improved HF/HCl solution. Surf Coat Technol 198:314–318CrossRef Iliescu C, Jing J, Tay FEH, Miao J, Sun T (2005) Characterization of masking layers for deep wet etching of glass in an improved HF/HCl solution. Surf Coat Technol 198:314–318CrossRef
Zurück zum Zitat Jackman RJ, Brittain ST, Whitesides GM (1998) Fabrication of three-dimensional microstructures by electrochemically welding structures formed by microcontact printing on planar and curved substrates. J Microelectromech Syst 7:261–266CrossRef Jackman RJ, Brittain ST, Whitesides GM (1998) Fabrication of three-dimensional microstructures by electrochemically welding structures formed by microcontact printing on planar and curved substrates. J Microelectromech Syst 7:261–266CrossRef
Zurück zum Zitat Jiang YG, Ono T, Esashi M (2006) High aspect ratio spiral microcoils fabricated by a silicon lost molding technique. J Micromech Microeng 16:1057–1061CrossRef Jiang YG, Ono T, Esashi M (2006) High aspect ratio spiral microcoils fabricated by a silicon lost molding technique. J Micromech Microeng 16:1057–1061CrossRef
Zurück zum Zitat Kim Y, Llamas-Garro I, Baek CW, Kim JM, Kim YK (2009) New release technique of a thick sacrificial layer and residue effects on novel half-coaxial transmission line filters. J Micromech Microeng 19:1–6 Kim Y, Llamas-Garro I, Baek CW, Kim JM, Kim YK (2009) New release technique of a thick sacrificial layer and residue effects on novel half-coaxial transmission line filters. J Micromech Microeng 19:1–6
Zurück zum Zitat Lacey ME, Subramanian R, Olson DL, Webb AG, Sweedler JV (1999) High-resolution NMR spectroscopy of sample volumes from 1 nL to 10 μL. Chem Rev 99(10):3133–3152CrossRef Lacey ME, Subramanian R, Olson DL, Webb AG, Sweedler JV (1999) High-resolution NMR spectroscopy of sample volumes from 1 nL to 10 μL. Chem Rev 99(10):3133–3152CrossRef
Zurück zum Zitat Li Y, Ahmad MM, Hand JW, Syms RRA, Gilderdale D, Collins DJ, Young IR (2007) Microcoils on structured silicon substrates for magnetic resonance detection. IEEE Sens J 7(9):1362–1369CrossRef Li Y, Ahmad MM, Hand JW, Syms RRA, Gilderdale D, Collins DJ, Young IR (2007) Microcoils on structured silicon substrates for magnetic resonance detection. IEEE Sens J 7(9):1362–1369CrossRef
Zurück zum Zitat Malba V, Maxwell R, Evans LB, Bernhardt AF, Cosman M, Yan K (2003) Laser-lathe lithography—a novel method for manufacturing nuclear magnetic resonance microcoils. Biomed Microdevices 5(1):21–27CrossRef Malba V, Maxwell R, Evans LB, Bernhardt AF, Cosman M, Yan K (2003) Laser-lathe lithography—a novel method for manufacturing nuclear magnetic resonance microcoils. Biomed Microdevices 5(1):21–27CrossRef
Zurück zum Zitat Massin C, Vincent F, Homsy A, Ehrmann K, Boero G, Besse P-A, Daridon A, Verpoorte E, de Rooij NF, Popovic RS (2003) Planar microcoil-based microfluidic NMR probes. J Magn Reson 164:242–255CrossRef Massin C, Vincent F, Homsy A, Ehrmann K, Boero G, Besse P-A, Daridon A, Verpoorte E, de Rooij NF, Popovic RS (2003) Planar microcoil-based microfluidic NMR probes. J Magn Reson 164:242–255CrossRef
Zurück zum Zitat Olson DL, Peck TL, Webb AG, Magin RL, Sweedler JV (1995) High-resolution microcoil 1H-NMR for mass-limited, nanoliter-volume samples. Science 270:1967CrossRef Olson DL, Peck TL, Webb AG, Magin RL, Sweedler JV (1995) High-resolution microcoil 1H-NMR for mass-limited, nanoliter-volume samples. Science 270:1967CrossRef
Zurück zum Zitat Olson DL, Lacey ME, Sweedler JV (1998) High-resolution microcoil NMR for analysis of mass-limited, nanoliter samples. Anal Chem 70:645–650CrossRef Olson DL, Lacey ME, Sweedler JV (1998) High-resolution microcoil NMR for analysis of mass-limited, nanoliter samples. Anal Chem 70:645–650CrossRef
Zurück zum Zitat Seeber DA, Hoftiezer JH, Daniel WB, Rutgers MA, Pennington CH (2000) Triaxial magnetic field gradient system for microcoil magnetic resonance imaging. Rev Sci Instrum 71:4263–4272CrossRef Seeber DA, Hoftiezer JH, Daniel WB, Rutgers MA, Pennington CH (2000) Triaxial magnetic field gradient system for microcoil magnetic resonance imaging. Rev Sci Instrum 71:4263–4272CrossRef
Zurück zum Zitat Song JS, Lee S, Jung SH, Cha GC, Mun MS (2009) Improved biocompatibility of parylene-C files prepared by chemical vapor deposition and the subsequent plasma treatment. J Appl Polym Sci 112:3677–3685CrossRef Song JS, Lee S, Jung SH, Cha GC, Mun MS (2009) Improved biocompatibility of parylene-C files prepared by chemical vapor deposition and the subsequent plasma treatment. J Appl Polym Sci 112:3677–3685CrossRef
Zurück zum Zitat Woytasik M, Ginefri JC, Raynaud JS, Poirier-Quinot M, Dufour-Gergam E, Grandchamp J, Girard O, Robert P, Gilles JP, Martincic E, Darrasse L (2007) Characterization of flexible RF microcoils dedicated to local MRI. Microsyst Technol 13:1575–1580CrossRef Woytasik M, Ginefri JC, Raynaud JS, Poirier-Quinot M, Dufour-Gergam E, Grandchamp J, Girard O, Robert P, Gilles JP, Martincic E, Darrasse L (2007) Characterization of flexible RF microcoils dedicated to local MRI. Microsyst Technol 13:1575–1580CrossRef
Metadaten
Titel
Multilayer high-aspect-ratio RF coil for NMR applications
verfasst von
C. Y. Hsieh
Y. T. Yeh
L. S. Fan
Publikationsdatum
01.08.2011
Verlag
Springer-Verlag
Erschienen in
Microsystem Technologies / Ausgabe 8/2011
Print ISSN: 0946-7076
Elektronische ISSN: 1432-1858
DOI
https://doi.org/10.1007/s00542-011-1305-z

Weitere Artikel der Ausgabe 8/2011

Microsystem Technologies 8/2011 Zur Ausgabe

Neuer Inhalt