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Journal of Polymer Research
Erschienen in: Journal of Polymer Research 6/2021

01.06.2021 | ORIGINAL PAPER

Two Co(II) coordination polymers: magnetic properties and prevention activity on hypertension during pregnancy by regulating the VEGF in vascular endothelial cells

verfasst von: Hui-Jie Ni, Ji-Xian Zhang, Xiao-Wei Yang

Erschienen in: Journal of Polymer Research | Ausgabe 6/2021

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Abstract

Two new Co(II) coordination polymers, namely, [Co(L)(bpe)(H2O)]n·[Co0.5(bpe)0.5(H2O)2]n·nH2O (1) and [Co2(L)(bpe)(μ3-OH)(H2O)]n·3nH2O (2) have been prepared via utilizing the flexible ligands of 1,2-bis(4-pyridyl)ethane (bpe) and 5-(3-carboxybenzyloxy)-isophthalic acid (H3L) under various conditions. The two compounds’ magnetic properties reveal that between the consecutive metal ions, there exists the antiferromagnetic coupling. Their application values on the hypertension during pregnancy prevention were assessed and their specific mechanism was also studied in meantime. Firstly, the VEGF (vascular endothelial growth factor) relative expression in vascular endothelial cells was determined via the real time reverse transcription-polymerase. In addition to this, in vascular endothelial cells, the inflammatory response was detected through ELISA (enzyme linked immunosorbent assay) detection by measuring the inflammatory cytokines releasing.
Vorheriger Artikel Production and investigation of mechanical properties of graphene/polystyrene nano composites
Nächster Artikel Porous organic/inorganic polymers based on double-decker silsesquioxane for high-performance energy storage

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Metadaten
Titel
Two Co(II) coordination polymers: magnetic properties and prevention activity on hypertension during pregnancy by regulating the VEGF in vascular endothelial cells
verfasst von
Hui-Jie Ni
Ji-Xian Zhang
Xiao-Wei Yang
Publikationsdatum
01.06.2021
Verlag
Springer Netherlands
Erschienen in
Journal of Polymer Research / Ausgabe 6/2021
Print ISSN: 1022-9760
Elektronische ISSN: 1572-8935
DOI
https://doi.org/10.1007/s10965-021-02572-4

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