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Polymer Bulletin

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03.12.2019 | Original Paper

Synthesis of poly(2-ethyl-2-oxazoline)-b-poly(ε-caprolactone) conjugates by a new modular strategy

verfasst von: Umut Ugur Ozkose, Ozgur Yilmaz, Onur Alpturk

Erschienen in: Polymer Bulletin | Ausgabe 11/2020

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Abstract

Amphiphilic block copolymers where hydrophobicity and hydrophilicity coincide are essential building blocks for many supramolecular systems. By this time, polyethylene glycol (PEG) has been a conventional choice to constitute hydrophilicity; however, it suffers from certain drawbacks, severely limiting its use in these compounds. To date, one potential modality to overcome this complication is to utilize poly(2-ethyl-2-oxazoline) (PEtOx) instead, given that this also-hydrophilic polymer is very comparable to PEG, in many ways. In this regard, amphiphilic block copolymers harboring PEtOx and synthetic approaches to access these polymeric materials have been documented in the literature. Within this scope, we crafted a modular approach for the synthesis of poly(2-ethyl-2-oxazoline)-b-poly(ε-caprolactone) to govern its molecular structure. Herein, we extend this work and report a novel poly(2-ethyl-2-oxazoline)-b-poly(ε-caprolactone) derivative with electrophilic moiety on terminal position. We believe that this novel design could lead up to expeditious synthesis of block copolymer-biomolecule conjugates, which are of paramount significance for many applications.

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Vorheriger Artikel Synthesis and properties of degradable gels and porous polymers including acetal group in the network structure by addition reaction of multi-functional phenols and divinyl ether compounds

Nächster Artikel New polymer systems based on polyethylene glycol: synthesis, characterization, and study of the solubility behavior

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Titel: Synthesis of poly(2-ethyl-2-oxazoline)-b-poly(ε-caprolactone) conjugates by a new modular strategy
verfasst von: Umut Ugur Ozkose
Ozgur Yilmaz
Onur Alpturk
Publikationsdatum: 03.12.2019
Verlag: Springer Berlin Heidelberg
Erschienen in: Polymer Bulletin / Ausgabe 11/2020
Print ISSN: 0170-0839
Elektronische ISSN: 1436-2449
DOI: https://doi.org/10.1007/s00289-019-03038-w

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