nach oben

Cellulose

Erschienen in:

10.12.2022 | Review Paper

Use of nanocellulose in the intracellular delivery of biological and non-biological drugs: a review

verfasst von: Navinchandra V. Puppala, Purnima Doddipatla, Gireesha Mohannath

Erschienen in: Cellulose | Ausgabe 3/2023

Einloggen

Aktivieren Sie unsere intelligente Suche, um passende Fachinhalte oder Patente zu finden.

search-config

KI-gestützte Suche

Aus

Abstract

The need for natural, biodegradable, and biocompatible nanomaterials in drug delivery led to a great deal of interest in developing nanocellulose-based materials. This article emphasizes the potential of different types of nanocellulose in improving targeted intracellular drug delivery of biological and non-biological therapeutic molecules. Several new concepts and methods of employing nanocellulose to deliver therapeutic molecules, including less-studied biological agents, have been reviewed. Different types of nanocellulose, methods to extract or synthesize them, and various factors like size, shape, surface charge, hydrophilicity, etc. that affect intracellular drug delivery have also been discussed. Lastly, we discuss the current limitations associated with the extraction/synthesis of nanocellulose and its usage in targeted drug delivery, along with future prospects, including possible solutions to address the current challenges.

Nächster Artikel Conformational characteristics of cellulose sulfoacetate chains and their comparison with other cellulose derivatives

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Technik"

Online-Abonnement

Mit Springer Professional "Technik" erhalten Sie Zugriff auf:

über 67.000 Bücher
über 390 Zeitschriften

aus folgenden Fachgebieten:

Automobil + Motoren
Bauwesen + Immobilien
Business IT + Informatik
Elektrotechnik + Elektronik
Energie + Nachhaltigkeit
Maschinenbau + Werkstoffe

Jetzt Wissensvorsprung sichern!

Jetzt informieren

Springer Professional "Wirtschaft+Technik"

Online-Abonnement

Mit Springer Professional "Wirtschaft+Technik" erhalten Sie Zugriff auf:

über 102.000 Bücher
über 537 Zeitschriften

aus folgenden Fachgebieten:

Automobil + Motoren
Bauwesen + Immobilien
Business IT + Informatik
Elektrotechnik + Elektronik
Energie + Nachhaltigkeit
Finance + Banking
Management + Führung
Marketing + Vertrieb
Maschinenbau + Werkstoffe
Versicherung + Risiko

Jetzt Wissensvorsprung sichern!

Jetzt informieren

Auta R, Adamus G, Kwiecień M, Radecka I, Hooley P (2017) Production and characterization of bacterial cellulose before and after enzymatic hydrolysis. Afr J Biotechnol 16:470–482. https://doi.org/10.5897/AJB2016.15486CrossRef

Auvinen VV, Virtanen J, Merivaara A et al (2020) Modulating sustained drug release from nanocellulose hydrogel by adjusting the inner geometry of implantable capsules. J Drug Deliv Sci Technol 57:101625. https://doi.org/10.1016/j.jddst.2020.101625CrossRef

Bacakova L, Pajorova J, Tomkova M et al (2020) Applications of nanocellulose/nanocarbon composites: focus on biotechnology and medicine. Nanomaterials 10:196. https://doi.org/10.3390/nano10020196CrossRefPubMedPubMedCentral

Bahadar H, Maqbool F, Niaz K, Abdollahi M (2016) Toxicity of nanoparticles and an overview of current experimental models. Iran Biomed J 20:1–11. https://doi.org/10.7508/ibj.2016.01.001CrossRefPubMedPubMedCentral

Banerjee M, Saraswatula S, Willows LG et al (2018) Pharmaceutical crystallization in surface-modified nanocellulose organogels. J Mater Chem B 6:7317–7328. https://doi.org/10.1039/C8TB01554FCrossRefPubMed

Barcelos CA, Rocha VA, Groposo C (2015) Enzymes and accessory proteins involved in the hydrolysis of lignocellulosic biomass for bioethanol production. Mycol Curr Futur Dev. https://doi.org/10.2174/9781681080741115010005CrossRef

Bawa P, Pillay V, Choonara YE, Du Toit LC (2009) Stimuli-responsive polymers and their applications in drug delivery. Biomed Mater. https://doi.org/10.1088/1748-6041/4/2/022001CrossRefPubMed

Beekmann U, Schmölz L, Lorkowski S et al (2020) Process control and scale-up of modified bacterial cellulose production for tailor-made anti-inflammatory drug delivery systems. Carbohydr Polym 236:116062. https://doi.org/10.1016/j.carbpol.2020.116062CrossRefPubMed

Behzadi S, Serpooshan V, Tao W et al (2017) Cellular uptake of nanoparticles: journey inside the cell. Chem Soc Rev 46:4218–4244. https://doi.org/10.1039/c6cs00636aCrossRefPubMedPubMedCentral

Ben-Haim N, Broz P, Marsch S et al (2008) Cell-specific integration of artificial organelles based on functionalized polymer vesicles. Nano Lett 8:1368–1373. https://doi.org/10.1021/nl080105gCrossRefPubMed

Benjamin O, Goyal A, Lappin SL (2022) Disease modifying anti-rheumatic drugs (DMARD)

Borba PB, Meneguin AB, Silva JM et al (2022) Bacterial nanocellulose containing diethylditiocarbamate bio-curatives: physicochemical characterization and drug delivery evaluation. Cellulose 29:1557–1565. https://doi.org/10.1007/s10570-021-04360-1CrossRef

Breijaert TC, Daniel G, Hedlund D et al (2022) Self-assembly of ferria—Nanocellulose composite fibres. Carbohydr Polym 291:119560. https://doi.org/10.1016/j.carbpol.2022.119560CrossRefPubMed

Brinkhuis RP, Rutjes FPJT, Van Hest JCM (2011) Polymeric vesicles in biomedical applications. Polym Chem 2:1449–1462. https://doi.org/10.1039/c1py00061fCrossRef

Camargo LA, Pereira SC, Correa AC et al (2016) Feasibility of manufacturing cellulose nanocrystals from the solid residues of second-generation ethanol production from sugarcane bagasse. Bioenergy Res 9:894–906. https://doi.org/10.1007/s12155-016-9744-0CrossRef

Catalán J, Ilves M, Järventaus H et al (2015) Genotoxic and immunotoxic effects of cellulose nanocrystals in vitro. Environ Mol Mutagen 56:171–182. https://doi.org/10.1002/em.21913CrossRefPubMed

Chakraborty A, Sain M, Kortschot M (2005) Cellulose microfibrils: a novel method of preparation using high shear refining and cryocrushing. Holzforschung 59:102–107. https://doi.org/10.1515/HF.2005.016CrossRef

Chen H (2015) Lignocellulose biorefinery engineering. Elsevier

Chen L, Wang Q, Hirth K et al (2015) Tailoring the yield and characteristics of wood cellulose nanocrystals (CNC) using concentrated acid hydrolysis. Cellulose 22:1753–1762. https://doi.org/10.1007/s10570-015-0615-1CrossRef

Ching YC, Gunathilake TMSU, Chuah CH et al (2019) Curcumin/Tween 20-incorporated cellulose nanoparticles with enhanced curcumin solubility for nano-drug delivery: characterization and in vitro evaluation. Cellulose 26:5467–5481. https://doi.org/10.1007/s10570-019-02445-6CrossRef

Chithrani BD, Ghazani AA, Chan WCW (2006) Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells. Nano Lett 6:662–668. https://doi.org/10.1021/nl052396oCrossRefPubMed

Czaja W, Kyryliouk D, Depaula CA, Buechter DD (2014) Oxidation of γ-irradiated microbial cellulose results in bioresorbable, highly conformable biomaterial. J Appl Polym Sci 131:1–12. https://doi.org/10.1002/app.39995CrossRef

de Lima R, Feitosa LO, Maruyama CR et al (2012) Evaluation of the genotoxicity of cellulose nanofibers. Int J Nanomed 7:3555–3565. https://doi.org/10.2147/IJN.S30596CrossRef

de Oliveira Júnior SD, Asevedo EA, de Araújo JS et al (2020) Enzymatic extract of Aspergillus fumigatus CCT 7873 for hydrolysis of sugarcane bagasse and generation of cellulose nanocrystals (CNC). Biomass Convers Biorefinery. https://doi.org/10.1007/s13399-020-01020-5CrossRef

De Verdière AC, Dubernet C, Némati F et al (1997) Reversion of multidrug resistance with polyalkylcyanoacrylate nanoparticles: towards a mechanism of action. Br J Cancer 76:198–205. https://doi.org/10.1038/bjc.1997.362CrossRefPubMed

Dong S, Hirani AA, Colacino KR et al (2012) Cytotoxicity and cellular uptake of cellulose nanocrystals. Nano Life 02:1241006. https://doi.org/10.1142/s1793984412410061CrossRef

Eekels JJ, Sagnier S, Geerts D et al (2012) Inhibition of HIV-1 replication with stable RNAi-mediated knockdown of autophagy factors. Virol J 9:69. https://doi.org/10.1186/1743-422X-9-69CrossRefPubMedPubMedCentral

Endes C, Camarero-Espinosa S, Mueller S et al (2016) A critical review of the current knowledge regarding the biological impact of nanocellulose. J Nanobiotechnol 14:78. https://doi.org/10.1186/s12951-016-0230-9CrossRef

Ferrer A, Filpponen I, Rodríguez A et al (2012) Valorization of residual Empty Palm Fruit Bunch Fibers (EPFBF) by microfluidization: production of nanofibrillated cellulose and EPFBF nanopaper. Bioresour Technol 125:249–255. https://doi.org/10.1016/j.biortech.2012.08.108CrossRefPubMed

Fiorati A, Negrini NC, Baschenis E et al (2020) TEMPO-nanocellulose/Ca²⁺ hydrogels: ibuprofen drug diffusion and in vitro cytocompatibility. Materials 13:183. https://doi.org/10.3390/ma13010183CrossRefPubMedPubMedCentral

Fu PP, Xia Q, Hwang HM et al (2014) Mechanisms of nanotoxicity: generation of reactive oxygen species. J Food Drug Anal 22:64–75. https://doi.org/10.1016/j.jfda.2014.01.005CrossRefPubMedPubMedCentral

Geng Y, Dalhaimer P, Cai S et al (2007) Shape effects of filaments versus spherical particles in flow and drug delivery. Nat Nanotechnol 2:249–255. https://doi.org/10.1038/nnano.2007.70CrossRefPubMedPubMedCentral

Guo R, Li J, Chen C et al (2021) Biomimetic 3D bacterial cellulose-graphene foam hybrid scaffold regulates neural stem cell proliferation and differentiation. Colloids Surf B Biointerfaces 200:111590. https://doi.org/10.1016/j.colsurfb.2021.111590CrossRefPubMed

Gupta RD, Raghav N (2020) Nano-crystalline cellulose: Preparation, modification and usage as sustained release drug delivery excipient for some non-steroidal anti-inflammatory drugs. Int J Biol Macromol 147:921–930. https://doi.org/10.1016/j.ijbiomac.2019.10.057CrossRefPubMed

Hasan N, Rahman L, Kim SH et al (2020) Recent advances of nanocellulose in drug delivery systems. J Pharm Investig 50:553–572. https://doi.org/10.1007/s40005-020-00499-4CrossRef

Herreros-López A, Carini M, Da Ros T, Carofiglio T, Marega C, La Parola V, Rapozzi V, Xodo LE, Alshatwi Ali A, Hadad C, Prato M (2017) Nanocrystalline cellulose-fullerene: novel conjugates. Carbohydr Polym. 164:92–101. https://doi.org/10.1016/j.carbpol.2017.01.068CrossRefPubMed

Hu H, Xiu KM, Xu SL et al (2013) Functionalized layered double hydroxide nanoparticles conjugated with disulfide-linked polycation brushes for advanced gene delivery. Bioconjug Chem 24:968–978. https://doi.org/10.1021/bc300683yCrossRefPubMed

Hu H, Yuan W, Liu FS et al (2015) Redox-responsive polycation-functionalized cotton cellulose nanocrystals for effective cancer treatment. ACS Appl Mater Interfaces 7:8942–8951. https://doi.org/10.1021/acsami.5b02432CrossRefPubMed

Ilkar Erdagi S, Asabuwa Ngwabebhoh F, Yildiz U (2020a) Genipin crosslinked gelatin-diosgenin-nanocellulose hydrogels for potential wound dressing and healing applications. Int J Biol Macromol 149:651–663. https://doi.org/10.1016/j.ijbiomac.2020.01.279CrossRefPubMed

Ilkar Erdagi S, Ngwabebhoh FA, Yildiz U (2020b) Pickering stabilized nanocellulose-alginate: a diosgenin-mediated delivery of quinalizarin as a potent cyto-inhibitor in human lung/breast cancer cell lines. Mater Sci Eng C 109:110621. https://doi.org/10.1016/j.msec.2019.110621CrossRef

Zang S, Chen F, Dai J, Guo D, Tse W, Qu X, Ma D, Ji C (2010) RNAi-mediated knockdown of Notch-1 leads to cell growth inhibition and enhanced chemosensitivity in human breast cancer. Oncol Rep 23:893–899. https://doi.org/10.3892/or_00000712CrossRefPubMed

Kang X, Kuga S, Wang C et al (2018) Green preparation of cellulose nanocrystal and its application. ACS Sustain Chem Eng 6:2954–2960. https://doi.org/10.1021/acssuschemeng.7b02363CrossRef

Khine YY, Batchelor R, Raveendran R, Stenzel MH (2020) Photo-induced modification of nanocellulose: the design of self-fluorescent drug carriers. Macromol Rapid Commun 41:1900499. https://doi.org/10.1002/marc.201900499CrossRef

Kim D, Jeong J, Ryu JA et al (2020) In vitro evaluation of lignin-containing nanocellulose. Materials 13:1–12. https://doi.org/10.3390/ma13153365CrossRef

Kumar A, Singh Negi Y, Choudhary V, Kant Bhardwaj N (2020) Characterization of cellulose nanocrystals produced by acid-hydrolysis from sugarcane bagasse as agro-waste. J Mater Phys Chem 2:1–8. https://doi.org/10.12691/jmpc-2-1-1CrossRef

Kümmerer K, Menz J, Schubert T, Thielemans W (2011) Biodegradability of organic nanoparticles in the aqueous environment. Chemosphere 82:1387–1392. https://doi.org/10.1016/j.chemosphere.2010.11.069CrossRefPubMed

Lee KY, Tammelin T, Kiiskinen H et al (2012) Nano-fibrillated cellulose vs bacterial cellulose: reinforcing ability of nanocellulose obtained topdown or bottom-up. In: ECCM 2012—Composites at Venice, Proceedings of the 15th European conference on composite materials, pp 24–28

Li N, Yang L, Pan C et al (2020) Naturally-occurring bacterial cellulose-hyperbranched cationic polysaccharide derivative/MMP-9 siRNA composite dressing for wound healing enhancement in diabetic rats. Acta Biomater 102:298–314. https://doi.org/10.1016/j.actbio.2019.11.005CrossRefPubMed

Li S, Zhao Z, Wu W et al (2016) Dual pH-responsive micelles with both charge-conversional property and hydrophobic-hydrophilic transition for effective cellular uptake and intracellular drug release. Polym Chem 7:2202–2208. https://doi.org/10.1039/c6py00177gCrossRef

Lin N, Dufresne A (2014) Nanocellulose in biomedicine: current status and future prospect. Eur Polym J 59:302–325. https://doi.org/10.1016/j.eurpolymj.2014.07.025CrossRef

Lin Q, Yan Y, Liu X et al (2020) Production of xylooligosaccharide, nanolignin, and nanocellulose through a fractionation strategy of corncob for biomass valorization. Ind Eng Chem Res 59:17429–17439. https://doi.org/10.1021/acs.iecr.0c02161CrossRef

Lin X, Zhao N, Yan P et al (2015) The shape and size effects of polycation functionalized silica nanoparticles on gene transfection. Acta Biomater 11:381–392. https://doi.org/10.1016/j.actbio.2014.09.004CrossRefPubMed

Liu C, Li B, Du H et al (2016) Properties of nanocellulose isolated from corncob residue using sulfuric acid, formic acid, oxidative and mechanical methods. Carbohydr Polym 151:716–724. https://doi.org/10.1016/j.carbpol.2016.06.025CrossRefPubMed

Loh EYX, Fauzi MB, Ng MH et al (2020) Insight into delivery of dermal fibroblast by non-biodegradable bacterial nanocellulose composite hydrogel on wound healing. Int J Biol Macromol 159:497–509. https://doi.org/10.1016/j.ijbiomac.2020.05.011CrossRefPubMed

Lorenz S, Hauser CP, Autenrieth B et al (2010) The softer and more hydrophobic the better: influence of the side chain of polymethacrylate nanoparticles for cellular uptake. Macromol Biosci 10:1034–1042. https://doi.org/10.1002/mabi.201000099CrossRefPubMed

Luo X, Zhang H, Cao Z et al (2016) A simple route to develop transparent doxorubicin-loaded nanodiamonds/cellulose nanocomposite membranes as potential wound dressings. Carbohydr Polym 143:231–238. https://doi.org/10.1016/j.carbpol.2016.01.076CrossRefPubMed

Maestri CA, Motta A, Moschini L et al (2020) Composite nanocellulose-based hydrogels with spatially oriented degradation and retarded release of macromolecules. J Biomed Mater Res Part A 108:1509–1519. https://doi.org/10.1002/jbm.a.36922CrossRef

Mahmoud KA, Mena JA, Male KB et al (2010) Effect of surface charge on the cellular uptake and cytotoxicity of fluorescent labeled cellulose nanocrystals. ACS Appl Mater Interfaces 2:2924–2932. https://doi.org/10.1021/am1006222CrossRefPubMed

Mao X, Li X, Mao X et al (2014) Inhibition of hepatitis C virus by an M1GS ribozyme derived from the catalytic RNA subunit of Escherichia coli RNase P. Virol J 11:86. https://doi.org/10.1186/1743-422X-11-86CrossRefPubMedPubMedCentral

Mbituyimana B, Mao L, Hu S et al (2021) Bacterial cellulose/glycolic acid/glycerol composite membrane as a system to deliver glycolic acid for anti-aging treatment. J Bioresour Bioprod 6:129–141. https://doi.org/10.1016/j.jobab.2021.02.003CrossRef

Meerovich I, Dash AK (2019) Polymersomes for drug delivery and other biomedical applications. Materials for biomedical engineering. Elsevier, pp 269–309CrossRef

Menas AL, Yanamala N, Farcas MT et al (2017) Fibrillar vs crystalline nanocellulose pulmonary epithelial cell responses: cytotoxicity or inflammation? Chemosphere 171:671–680. https://doi.org/10.1016/j.chemosphere.2016.12.105CrossRefPubMed

Meneguin AB, da Silva BH, Sábio RM et al (2020) Spray-dried bacterial cellulose nanofibers: a new generation of pharmaceutical excipient intended for intestinal drug delivery. Carbohydr Polym 249:116838. https://doi.org/10.1016/j.carbpol.2020.116838CrossRefPubMed

Mohan D, Khairullah NF, How YP et al (2020) 3D printed laminated CaCO₃-nanocellulose films as controlled-release 5-fluorouracil. Polymers 12:986. https://doi.org/10.3390/POLYM12040986CrossRefPubMedPubMedCentral

Mudshinge SR, Deore AB, Patil S, Bhalgat CM (2011) Nanoparticles: emerging carriers for drug delivery. Saudi Pharm J 19:129–141. https://doi.org/10.1016/j.jsps.2011.04.001CrossRefPubMedPubMedCentral

Nasir M, Hashim R, Sulaiman O, Asim M (2017) Nanocellulose: preparation methods and applications. Cellulose-reinforced nanofibre composites: production, properties and applications. Elsevier, pp 261–276CrossRef

Ndong Ntoutoume GMA, Grassot V, Brégier F et al (2017) PEI-cellulose nanocrystal hybrids as efficient siRNA delivery agents—Synthesis, physicochemical characterization and in vitro evaluation. Carbohydr Polym 164:258–267. https://doi.org/10.1016/j.carbpol.2017.02.004CrossRefPubMed

Ning L, You C, Zhang Y et al (2020) Synthesis and biological evaluation of surface-modified nanocellulose hydrogel loaded with paclitaxel. Life Sci 241:117137. https://doi.org/10.1016/j.lfs.2019.117137CrossRefPubMed

Nishiguchi A, Taguchi T (2020a) Sustained-immunostimulatory nanocellulose scaffold to enhance vaccine efficacy. J Biomed Mater Res Part A 108:1159–1170. https://doi.org/10.1002/jbm.a.36890CrossRef

Nishiguchi A, Taguchi T (2020b) Development of an immunosuppressive camouflage-coating platform with nanocellulose and cell membrane vesicles. J Biomater Sci Polym Ed 31:1912–1924. https://doi.org/10.1080/09205063.2020.1783060CrossRefPubMed

O’donnell KL, Oporto-Velásquez GS, Comolli N (2020) Evaluation of acetaminophen release from biodegradable poly (Vinyl alcohol) (PVA) and nanocellulose films using a multiphase release mechanism. Nanomaterials 10:301. https://doi.org/10.3390/nano10020301CrossRefPubMedPubMedCentral

Pachuau L (2017) Application of nanocellulose for controlled drug delivery. Nanocellulose and nanohydrogel matrices: biotechnological and biomedical applications. Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, pp 1–19

Patel DK, Dutta SD, Ganguly K, Lim KT (2021) Multifunctional bioactive chitosan/cellulose nanocrystal scaffolds eradicate bacterial growth and sustain drug delivery. Int J Biol Macromol 170:178–188. https://doi.org/10.1016/j.ijbiomac.2020.12.145CrossRefPubMed

Pereira B, Arantes V (2020) Production of cellulose nanocrystals integrated into a biochemical sugar platform process via enzymatic hydrolysis at high solid loading. Ind Crops Prod 152:112377. https://doi.org/10.1016/j.indcrop.2020.112377CrossRef

Pereira B, Arantes V (2018) Nanocelluloses from sugarcane biomass. In: Adv sugarcane biorefinery technol commer policy issues paradig shift bioethanol by-products, pp 179–196. https://doi.org/10.1016/B978-0-12-804534-3.00009-4

Phanthong P, Guan G, Ma Y et al (2016) Effect of ball milling on the production of nanocellulose using mild acid hydrolysis method. J Taiwan Inst Chem Eng 60:617–622. https://doi.org/10.1016/j.jtice.2015.11.001CrossRef

Plackett D, Letchford K, Jackson J, Burt H (2014) A review of nanocellulose as a novel vehicle for drug delivery. Nord Pulp Pap Res J 29:105–118. https://doi.org/10.3183/npprj-2014-29-01-p105-118CrossRef

Plappert SF, Liebner FW, Konnerth J, Nedelec JM (2019) Anisotropic nanocellulose gel–membranes for drug delivery: tailoring structure and interface by sequential periodate–chlorite oxidation. Carbohydr Polym 226:115306. https://doi.org/10.1016/j.carbpol.2019.115306CrossRefPubMed

Plermjai K, Boonyarattanakalin K, Mekprasart W et al (2018) Extraction and characterization of nanocellulose from sugarcane bagasse by ball-milling-assisted acid hydrolysis. In: AIP Conf Proc. https://doi.org/10.1063/1.5053181

Pötzinger Y, Rabel M, Ahrem H et al (2018) Polyelectrolyte layer assembly of bacterial nanocellulose whiskers with plasmid DNA as biocompatible non-viral gene delivery system. Cellulose 25:1939–1960. https://doi.org/10.1007/s10570-018-1664-zCrossRef

Rahimi Kord Sofla M, Brown RJ, Tsuzuki T, Rainey TJ (2016) A comparison of cellulose nanocrystals and cellulose nanofibres extracted from bagasse using acid and ball milling methods. Adv Nat Sci Nanosci Nanotechnol 7:035004. https://doi.org/10.1088/2043-6262/7/3/035004CrossRef

Ramesh S, Doddipatla P, Pamidipati S (2021) Optimization of parameters for biological pre-treatment route for the production of nanocellulose from sugarcane bagasse. Biomass Convers Biorefinery. https://doi.org/10.1007/s13399-021-01306-2CrossRef

Ribeiro RSA, Pohlmann BC, Calado V et al (2019) Production of nanocellulose by enzymatic hydrolysis: trends and challenges. Eng Life Sci 19:279–291. https://doi.org/10.1002/elsc.201800158CrossRefPubMedPubMedCentral

Riccio BVF, Klosowski AB, Prestes E et al (2021) Chitosan/nanocellulose-based bionanocomposite films for controlled betamethasone and silver sulfadiazine delivery. J Appl Polym Sci 138:1–13. https://doi.org/10.1002/app.50468CrossRef

Roberts MG, Yu Q, Keunen R et al (2020) Functionalization of cellulose nanocrystals with POEGMA copolymers via copper-catalyzed azide-alkyne cycloaddition for potential drug-delivery applications. Biomacromol 21:2014–2023. https://doi.org/10.1021/acs.biomac.9b01713CrossRef

Roobol SJ, Hartjes TA, Slotman JA et al (2020) Uptake and subcellular distribution of radiolabeled polymersomes for radiotherapy. Nanotheranostics 4:14–25. https://doi.org/10.7150/ntno.37080CrossRefPubMedPubMedCentral

Saneinezhad S, Bamoharram FF, Pordel M, Baharara J (2021) One pot and green ultrasonic catalytic synthesis of catenated nanocellulose by sodium 30-tungston pentaphosphate polyoxometalate as an interlocked surface stabilizer and its application for surface loading of l-ascorbic acid. Chem Pap 75:471–483. https://doi.org/10.1007/s11696-020-01296-xCrossRef

Serrano-Sevilla I, Artiga Á, Mitchell SG et al (2019) Natural polysaccharides for siRNA delivery: nanocarriers based on chitosan, hyaluronic acid, and their derivatives. Molecules 24:2570. https://doi.org/10.3390/molecules24142570CrossRefPubMedPubMedCentral

Shamsipour M, Mansouri AM, Moradipour P (2019) Temozolomide conjugated carbon quantum dots embedded in core/shell nanofibers prepared by coaxial electrospinning as an implantable delivery system for cell imaging and sustained drug release. AAPS PharmSciTech 20:259. https://doi.org/10.1208/s12249-019-1466-0CrossRefPubMed

Shazali NAH, Zaidi NE, Ariffin H et al (2019) Characterization and cellular internalization of Spherical Cellulose Nanocrystals (CNC) into normal and cancerous fibroblasts. Materials 12:3251. https://doi.org/10.3390/ma12193251CrossRefPubMedPubMedCentral

Simko M, Mattsson M-O (2014) Interactions between nanosized materials and the brain. Curr Med Chem 21:4200–4214. https://doi.org/10.2174/0929867321666140716100449CrossRefPubMedPubMedCentral

Singh R, Lillard JW (2009) Nanoparticle-based targeted drug delivery. Exp Mol Pathol 86:215–223. https://doi.org/10.1016/j.yexmp.2008.12.004CrossRefPubMedPubMedCentral

Singhsa P, Narain R, Manuspiya H (2018) Bacterial cellulose nanocrystals (BCNC) preparation and characterization from three bacterial cellulose sources and development of functionalized BCNCs as nucleic acid delivery systems. ACS Appl Nano Mater 1:209–221. https://doi.org/10.1021/acsanm.7b00105CrossRef

Siró I, Plackett D (2010) Microfibrillated cellulose and new nanocomposite materials: a review. Cellulose 17:459–494. https://doi.org/10.1007/s10570-010-9405-yCrossRef

Soman S, Chacko AS, Prasad VS et al (2018) Self-assembly of oleylamine modified nano-fibrillated cellulose from areca husk fibers into giant vesicles. Carbohydr Polym 182:69–74. https://doi.org/10.1016/j.carbpol.2017.11.010CrossRefPubMed

Svensson A, Nicklasson E, Harrah T et al (2005) Bacterial cellulose as a potential scaffold for tissue engineering of cartilage. Biomaterials 26:419–431. https://doi.org/10.1016/j.biomaterials.2004.02.049CrossRefPubMed

Taher MA, Zahan KA, Rajaie MA et al (2020) Nanocellulose as drug delivery system for honey as antimicrobial wound dressing. Mater Today Proc 31:14–17. https://doi.org/10.1016/j.matpr.2020.01.076CrossRef

Tanner P, Baumann P, Enea R et al (2011) Polymeric vesicles: from drug carriers to nanoreactors and artificial organelles. Acc Chem Res 44:1039–1049. https://doi.org/10.1021/ar200036kCrossRefPubMed

Tortorella S, Buratti VV, Maturi M et al (2020) Surface-modified nanocellulose for application in biomedical engineering and nanomedicine: a review. Int J Nanomed 15:9909–9937. https://doi.org/10.2147/IJN.S266103CrossRef

Trache D, Tarchoun AF, Derradji M et al (2020) Nanocellulose: from fundamentals to advanced applications. Front Chem. https://doi.org/10.3389/fchem.2020.00392CrossRefPubMedPubMedCentral

Vakilian H, Rojas EA, Rezaei LH, Behmanesh M (2020) Fabrication and optimization of linear PEI modified crystal nanocellulose as an efficient non-viral vector for in-vitro gene delivery. Rep Biochem Mol Biol 9:297–308. https://doi.org/10.29252/RBMB.9.3.297CrossRefPubMedPubMedCentral

Voronin D, Vikulina A, Voronin D et al (2020) Naturally derived nano- and micro-drug delivery vehicles: halloysite, vaterite and nanocellulose. New J Chem 44:5638–5655. https://doi.org/10.1039/c9nj06470bCrossRef

Wang J, Tavakoli J, Tang Y (2019) Bacterial cellulose production, properties and applications with different culture methods—A review. Carbohydr Polym 219:63–76. https://doi.org/10.1016/j.carbpol.2019.05.008CrossRefPubMed

Wang L, Wang C, Wang L et al (2021) Emulsion electrospun polylactic acid/ Apocynum venetum nanocellulose nanofiber membranes with controlled sea buckthorn extract release as a drug delivery system. Text Res J 91:1046–1055. https://doi.org/10.1177/0040517520970171CrossRef

Xu FJ, Yang WT (2011) Polymer vectors via controlled/living radical polymerization for gene delivery. Prog Polym Sci 36:1099–1131. https://doi.org/10.1016/j.progpolymsci.2010.11.005CrossRef

Yoffe AM, Prinsen P, Gopal A et al (2008) Predicting the sizes of large RNA molecules. Proc Natl Acad Sci USA 105:16153–16158. https://doi.org/10.1073/pnas.0808089105CrossRefPubMedPubMedCentral

Zhang L, Tsuzuki T, Wang X (2015) Preparation of cellulose nanofiber from softwood pulp by ball milling. Cellulose 22:1729–1741. https://doi.org/10.1007/s10570-015-0582-6CrossRef

Zhang S, Zhou S, Liu H et al (2020) Pinecone-inspired nanoarchitectured smart microcages enable nano/microparticle drug delivery. Adv Funct Mater 30:2002434. https://doi.org/10.1002/adfm.202002434CrossRefPubMedPubMedCentral

Zubair M, Arshad M, Ullah A (2021) Nanocellulose: a sustainable and renewable material for water and wastewater treatment. Natural Polymers-based green adsorbents for water treatment. Elsevier, pp 93–109CrossRef

Zuluaga R, Putaux JL, Restrepo A et al (2007) Cellulose microfibrils from banana farming residues: isolation and characterization. Cellulose 14:585–592. https://doi.org/10.1007/s10570-007-9118-zCrossRef

Titel: Use of nanocellulose in the intracellular delivery of biological and non-biological drugs: a review
verfasst von: Navinchandra V. Puppala
Purnima Doddipatla
Gireesha Mohannath
Publikationsdatum: 10.12.2022
Verlag: Springer Netherlands
Erschienen in: Cellulose / Ausgabe 3/2023
Print ISSN: 0969-0239
Elektronische ISSN: 1572-882X
DOI: https://doi.org/10.1007/s10570-022-04977-w

Springer Professional

Abstract

Bitte loggen Sie sich ein, um Zugang zu Ihrer Lizenz zu erhalten.

Sie haben noch keine Lizenz? Dann Informieren Sie sich jetzt über unsere Produkte:

Springer Professional "Technik"

Springer Professional "Wirtschaft+Technik"

Weitere Artikel der Ausgabe 3/2023

Stable construction of covalent organic framework/copper sulfide heterojunction on cellulose fibers with hyperbranched polyamide-amine for efficient photocatalytic degradation of organic dyes

Highly efficient and antibacterial uranium adsorbents derived from disubstituted amidoxime functionalized chitosan

Synthesis and application of functionalized ionic liquids-based imidazolium as solvent for cotton fibre cellulose dissolution

Bamboo phase quantification using thermogravimetric analysis: deconvolution and machine learning

Microstructure, chemical composition and thermal stability of alkali-treated bamboo fibers and parenchyma cells: effects of treatment time and temperature

Multifunctional esterified nanocellulose aerogel: impact of fatty chain length on oil/water separation and thermal insulation